Results 31 to 40 of about 4,278 (207)

In vitro ultrastructure and biodegradation of activated plasma albumin gel derived from human samples: A prospective observational study

Clinical Advances in Periodontics, EarlyView.
Abstract Background In soft tissue regeneration, the clinical efficacy of fibrin membranes has been a pressing concern. The key to this efficacy lies in the stability of membrane and its controlled absorption. Human serum albumin, with its influence on the formation and stability of fibrin networks, could hold the key to developing a more stable ...
Behzad Houshmand, Mohammadreza Talebi Ardakani, Farshad Armandei, Anahita Moscowchi, Ahmad Nazari, Jafar Ai, Mehdi Ekhlasmand Kermani, Hamoun Sabri   +7 more
wiley   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

Equine Veterinary Journal, EarlyView.
Abstract Background African horse sickness (AHS), caused by the vector‐borne African horse sickness virus (AHSV), is endemic to sub‐Saharan Africa and infection results in high mortality in naïve equine populations. Clinical signs include submucosal petechiae and prolonged bleeding post venepuncture indicative of hypocoagulation.
Eva Christina Schliewert, Emma H. Hooijberg, Amelia Goddard   +2 more
wiley   +1 more source

Heart‐On‐a‐Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell‐ and Tissue‐Scale Contractile Stresses

Small, EarlyView.
We present a heart‐on‐a‐chip platform embedded with ultrasoft mechanosensors for real‐time, multi‐scale stress mapping in engineered cardiac tissues. The system enables simultaneous quantification of local cell‐generated stresses and global tissue contractile forces.
Ali Mousavi, Christina‐Marie Boghdady, Shihao Cui, Sabra Rostami, Amid Shakeri, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Milica Radisic, Christopher Moraes, Houman Savoji   +10 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

Allergy, EarlyView.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong, Shaohua Lu, Zhenan Deng, Xuliang Cai, Huahao Shen, Guochao Shi, Changxing Ou, Zuofu Peng, Wei Jiang, Xiuhua Fu, Changzheng Wang, Meiling Jin, Zhongmin Qiu, Xiaoyang Wei, Wei Gu, Kewu Huang, Qiang Li, Xiangyan Zhang, Nanshan Zhong, Kian Fan Chung, Qingling Zhang, on behalf of C‐BIOPRED Consortium, Jiangtao Lin, Yongming Zhang, Nan Su, Xiaoyan Zhang, Qing Zhao, Ying Nong, Ping Chen, Tianyi Zhu, Binbin Ji, Yan Wang, Haitao Zhao, Jinbao Wang, Zhiyuan Zhang, Xiaona Yang, Chunhua Wei, Jing Han, Nong Yu, Qiang Li, Zhifu Yang, Yanhong Liu, Guohua Li, Huadong Guan, Shuping Zhang, Xiuhua Fu, Lihong Wang, Lingxin Meng, Zhenting Sun, Guangqin Cao, Lei Zhao, Kewu Huang, Hong Zhang, Wen Wang, Li An, Yangyu Chen, Yanli Gao, Xiaoxia Liu, Huifen Zhai, Fang Lin, Zhaohui Zhong, Zhongguang Wen, Yan Xiao, Jian Kang, Linfei Kong, Xinming Su, Xue Yan, Dijia Zhou, Huaping Tang, Wei Han, Yi Shu, Tintian Li, Lixin Xie, Hong Hu, Bo Liu, Yuzhu Li, Longmei Fan, Yue Zhang, Shifeng Zhao, Xiaofang Liu, Yuhong Wang, Xichun Zhang, Xinmao Wang, Pen Bai, Guangfa Wang, Yan Hu, Zhanwei Hu, Ju Cao, Bei He, Rui Wu, Xiaoyan Gai, Hong Zhu, Zhihai Han, Jiyi Meng, Wei Chen, Li Ma, Zhenqian Liu, Chunyang Zhang, Yan Zhang, Huahao Shen, Fugui Yan, Bin Shen, Xinghong Wang, Hao Zhang, Yinghua Yin, Jinkai Liu, Yanxiong Mao, Mao Huang, Xin Yao, Mao Huang, Ji Zhou, Zhenzhen Wu, Ping Yan, Yujie Zhang, Xinling Yang, Ningfei Ji, Fan Fei, Wanzhen Fu, Yi Yang, Yuting Shi, Wangjian Cha, Guochao Shi, Min Zhou, Wei Tang, Wei Chen, Jun Zhou, Wenjie Yang, Lei Zhu, Meiling Jin, Liping Xue, Li Li, Chun Li, Yin Gong, Qiang Li, Guogang Xie, Luhong Bao, Wuping Bao, Nianyun Li, Fengming Ding, Min Zhang, Zhongmin Qiu, Li Yu, Jungang Xie, Lingling Yi, Xianghuai Xu, Qiang Chen, Junjun Tang, Jinfu Xu, Xiaobing Ji, Jingyun Shi, Bo Su, Xiaojun Yang, Jiuwen Bai, Shuo Liang, Kebing Cheng, Wei Gu, Jiyong Ma, Yun Liu, Jun Ren, Shan Mao, Qingling Zhang, Baoqing Sun, Jiaxing Xie, Rihuang Qiu, Zhiqiang Wang, Peiyan Zhen, Wenting Luo, Changgao Zhong, Wei Luo, Yanqing Xie, Xinxin Yu, Wenting Yu, Wei He, Changzheng Wang, Qianli Ma, Min Wan, Mingzhou Zhang, Haining Li, Shaoxi Cai, Haijin Zhao, Yanmei Ye, Fang Zhou, Laiyu Liu, Guohua Huang, Jianpeng Liang, Jianping Zhao, Jungang Xie, Qiongjie Hu, Kaiyan Li, Wang Ni, Guohua Zheng, Weining Xiong, Lingling Yi, Xihu Du, Yunhui Zhang, Zhi Li, Xiaoqiong Tan, Feng Liao, Shenglan Wang, Yijiang Huang, Xinjun Cai, Kai Liu, Shaojing Sheng, Yihui Fu, Shenghua Sun, Qiang Zhang, Jinweng Cai, Ye Ling, Pin Chen, Hong Luo, Lv Liu, Zhijun Liu, Yuling Tang, Yusheng Yan, Guiyan Mo, Long Wen, Yinqun Zhu, Du Fan   +217 more
wiley   +1 more source

Veterinary Staphylo-Fibrinolysin.

Experimental Biology and Medicine, 1936
In an examination of 132 local strains of staphylococci† it was found that 80% of all strains originally isolated from internal human lesions are capable of liquefying human fibrin.1 Approximately 90% of all strains isolated from superficial human infections, however, and all strains isolated from veterinary lesions are non-lytic by the same in vitro ...
R. R. Madison, E. E. Dart
openaire   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

Allergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas, Inmaculada Martinez‐Saguer, Konrad Bork, Anastasios E. Germenis, Anete S. Grumach, Hanga Réka Horváth, Andrea Luczay, Andrea Zanichelli, Markus Magerl, Stephen Betschel, Emel Aygören‐Pürsün, Jonathan A. Bernstein, Isabelle Boccon‐Gibod, Teresa Caballero, Mauro Cancian, Sandra Christiansen, Danny M. Cohn, Francisco Contreras, Sansanee Craig, Camelia Isaic, Ankur Jindal, Constance H. Katelaris, Hilary J. Longhurst, Andrew MacGinnitie, Jonny Peter, Grzegorz Porebski, Avner Reshef, Dinh Van Nguyen, Bruce Zuraw, Anthony J. Castaldo, Henrik Balle Boysen, Timothy Craig, the Hereditary Angioedema Working Group (HAWK Group), Adil Adatia, Fiorella Adrianzen, Shimalee Andarawewa, Sladjana Andrejevic, Gabriel Emmanuel Arce‐Estrada, Ecem Ay, Adil Bahadir, Noemi Anna Bara, Marko Barešić, Krasimira Baynova, Shira Benor, Juliette Besson, Dharmagat Bhattarai, Patricia Bigas, Alexis Bocquet, Laurence Bouillet, Nicholas Brodszki, Thomas Buttgereit, Rosario Cabañas, Regis Campos, Asuman Çamyar, Orlane Chol, Stefan Cimbollek, Monica Colque Bayona, Cascia Day, Mats de Lange, Alex Fam, Davide Firinu, Tomas Freiberger, Johana Gil‐Serrano, Delphine Gobert, Dawn Goodyear, Maria del Mar Guilarte Clavero, Svetlana Hadvabova, David Hagin, Roman Hakl, George Harmat, Mensuda Hasanhodzic, Gocki Jacek, Joshua Jacobs, Rashmi Jain, Milos Jesenak, Amin Kanani, Daniela Kapustová, Boris Karanovic, Paul Keith, Tamar Kinaciyan, Pavlina Kralickova, Marcin Kurowski, Krzysztof Kuziemski, Rolando Laurel‐Laurel, Iris Leibovich‐Nassi, Gabriela Leon Zambrana, Ramon Lleonart, Lorena Lorenzo, Ferhat Maksudov, Ania Manson, Dusanka Markovic, Jayne McGucken, Nihal Mete Gokmen, Radovan Mijanovic, Vania Maria Miranda Saavedra, Irene Modestou, Sandra Nieto, Nora Nilsson, Patrik Nordenfelt, Francesca Perego, Angelica Petraroli, Elsa Phillips‐Angles, Alicia Prieto‐García, Michel Raguet, Marc Riedl, Matija Rijavec, Solange Rodrigues Valle, Yaryna Romanyshyn, Antoine Saut, Riccardo Senter, Branislav Šlenker, Marta Sobotkova, Peter J. Spaeth, Marcin Stobiecki, Linda Sundler Björkman, Mireille‐Maria Suttle, Agnes Szilágyi, Paola Triggianese, Kassiani Tzeli, Martina Vachová, Anna Valerieva, Solange Valle, Lilian Varga, Walter A. Wuillemin, Patrick Yong, Zhi Yuxiang, Liudmyla Zabrodska, Radana Zachova, Julia Zharankova   +128 more
wiley   +1 more source

Single‐Cell and Multiomic Analysis Reveals Neutrophil Heterogeneity and Prognostic Value in Cervical Lesions

Cancer Science, EarlyView.
This study is the first to identify a novel neutrophil subpopulation, N4, that is closely associated with the progression of cervical cancer. Characterized by high PLAU expression and specific interactions with tumor cells, N4 neutrophils were shown to promote tumor growth and immune modulation.
Ze Wang, Liang Zhuang, Shiyi Liu, Canhui Cao, Shimin Chen, Nan Yu, Xiaoyuan Huang, Tao Zhang   +7 more
wiley   +1 more source