Results 1 to 10 of about 88,167 (243)

Clarification of fibrin generation and degradation reaction processes of clot-fibrinolysis waveform in hemorrhagic disorders. [PDF]

open access: yesPLoS ONE
Clot-fibrinolysis waveform analysis (CFWA) is an assay used to simultaneously evaluate coagulation and fibrinolysis reactions. Although the assay detected the reaction via transmittance changes, there was no evidence that the transmittance changes ...
Tomoko Matsumoto   +9 more
doaj   +2 more sources

Fibrinolysis vs. primary percutaneous coronary intervention for ST‐segment elevation myocardial infarction cardiogenic shock

open access: yesESC Heart Failure, 2021
Aims There are limited contemporary data on the use of initial fibrinolysis in ST‐segment elevation myocardial infarction cardiogenic shock (STEMI‐CS). This study sought to compare the outcomes of STEMI‐CS receiving initial fibrinolysis vs.
Saraschandra Vallabhajosyula   +14 more
doaj   +1 more source

Measuring Fibrinolysis [PDF]

open access: yesHämostaseologie, 2021
AbstractPhysiological fibrinolysis under normal conditions progresses slowly, in contrast to coagulation which is triggered rapidly to stop bleeding and defend against microbial invasion. Methods to detect fibrinolysis abnormalities are less simple and poorly standardized compared with common coagulation tests.
openaire   +2 more sources

Effect of acute alcohol intoxication on mortality, coagulation, and fibrinolysis in trauma patients.

open access: yesPLoS ONE, 2021
BackgroundThe effect of alcohol on the outcome and fibrinolysis phenotype in trauma patients remains unclear. Hence, we performed this study to determine whether alcohol is a risk factor for mortality and fibrinolysis shutdown in trauma patients ...
Il-Jae Wang   +11 more
doaj   +1 more source

Fibrinolytic therapy use for ST-segment elevation myocardial infarction and long-term outcomes in China: 2-year results from the China Acute Myocardial Infarction Registry

open access: yesBMC Cardiovascular Disorders, 2023
Background Data on fibrinolytic therapy use for ST-segment elevation myocardial infarction (STEMI) and long-term clinical outcomes in developing countries are limited.
Chao Wu   +12 more
doaj   +1 more source

Global coagulation assays to measure in vitro fibrinolysis

open access: yesThrombosis Update, 2021
(249/250 words): Introduction: Fibrinolysis is a critical component of hemostasis associated with poor outcomes if not treated early and effectively. Successful hemostasis management requires close fibrinolysis monitoring. The study aimed to compare the
Joao D. Dias   +3 more
doaj   +1 more source

uPA-mediated plasminogen activation is enhanced by polyphosphate

open access: yesHaematologica, 2020
Tissue plasminogen activator (tPA) and urokinase (uPA) differ in their modes of action. Efficient tPA-mediated plasminogen activation requires binding to fibrin.
Claire S. Whyte, Nicola J. Mutch
doaj   +1 more source

Point-of-care diagnosis and monitoring of fibrinolysis resistance in the critically ill: results from a feasibility study

open access: yesCritical Care, 2023
Background Fibrinolysisis is essential for vascular blood flow maintenance and is triggered by endothelial and platelet release of tissue plasminogen activator (t-PA). In certain critical conditions, e.g.
Lucy A. Coupland   +7 more
doaj   +1 more source

Assessment of Fibrinolysis in Sepsis Patients with Urokinase Modified Thromboelastography. [PDF]

open access: yesPLoS ONE, 2015
Impairment of fibrinolysis during sepsis is associated with worse outcome. Early identification of this condition could be of interest. The aim of this study was to evaluate whether a modified point-of-care viscoelastic hemostatic assay can detect sepsis-
Mauro Panigada   +9 more
doaj   +1 more source

The state of the fibrinolytic system in HIV-infected pregnant women and parturient women with thrombohemorrhagic risk factors

open access: yesРепродуктивная эндокринология, 2020
Purpose of the study: to explore the status of the fibrinolytic system in HIV-infected pregnant women and parturient women. Materials and methods. 120 HIV-positive pregnant women with risk factors of thrombohemorrhagic complications were examined.
С. Є. Савченко   +4 more
doaj   +1 more source

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