Results 1 to 10 of about 131,232 (324)
ESC Heart Failure, 2021 Aims There are limited contemporary data on the use of initial fibrinolysis in ST‐segment elevation myocardial infarction cardiogenic shock (STEMI‐CS). This study sought to compare the outcomes of STEMI‐CS receiving initial fibrinolysis vs.
Saraschandra Vallabhajosyula +14 more
doaj +2 more sources
Global coagulation assays to measure in vitro fibrinolysis
Thrombosis Update, 2021 (249/250 words): Introduction: Fibrinolysis is a critical component of hemostasis associated with poor outcomes if not treated early and effectively. Successful hemostasis management requires close fibrinolysis monitoring. The study aimed to compare the
Joao D. Dias +3 more
doaj +2 more sources
Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation [PDF]
Europace, 2019 © The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which ...
Arachchillage, Deepa RJ +7 more
core +4 more sources
Clarification of fibrin generation and degradation reaction processes of clot-fibrinolysis waveform in hemorrhagic disorders. [PDF]
PLoS ONEClot-fibrinolysis waveform analysis (CFWA) is an assay used to simultaneously evaluate coagulation and fibrinolysis reactions. Although the assay detected the reaction via transmittance changes, there was no evidence that the transmittance changes ...
Tomoko Matsumoto +9 more
doaj +2 more sources
Halo fluorescence fibrinolysis test: a novel quantitative assay to evaluate fibrinolysis on established plasma clots [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Fibrinolysis is essential for dissolving blood clots and maintaining hemostasis. This process is primarily mediated by tissue-type plasminogen activator, which converts plasminogen into plasmin, thereby breaking down fibrin clots. Traditional
Zikou Liu +3 more
doaj +2 more sources
Blood Advances, 2018 : Individuals with factor XI (FXI) deficiency have a variable bleeding risk that cannot be predicted from plasma FXI antigen or activity. This limitation can result in under- or overtreatment of patients and risk of bleeding or thrombosis.
Gillian N. Gidley +5 more
doaj +2 more sources
Platelet protease nexin-1 limits fibrinolysis in patients with cirrhosis [PDF]
JHEP ReportsBackground & Aims: The role of protease nexin 1 (PN-1), a serine protease inhibitor that regulates both coagulation and fibrinolysis, is unknown in patients with cirrhosis. This study aimed to provide a comprehensive assessment of the role of PN-1 in
Alix Riescher-Tuczkiewicz +13 more
doaj +2 more sources
Thrombin Activatable Fibrinolysis Inhibitor (TAFI): An Updated Narrative Review
International Journal of Molecular Sciences, 2021 Thrombin activatable fibrinolysis inhibitor (TAFI), a proenzyme, is converted to a potent attenuator of the fibrinolytic system upon activation by thrombin, plasmin, or the thrombin/thrombomodulin complex.
M. Sillen, P. Declerck
semanticscholar +1 more source
Blood Advances, 2021 The high incidence of thrombotic events suggests a possible role of the contact system pathway in COVID-19 pathology. Here, we demonstrate altered levels of factor XII (FXII) and its activation products in critically ill COVID-19 patients in comparison
M. Wygrecka +24 more
semanticscholar +1 more source
Effect of acute alcohol intoxication on mortality, coagulation, and fibrinolysis in trauma patients.
PLoS ONE, 2021 BackgroundThe effect of alcohol on the outcome and fibrinolysis phenotype in trauma patients remains unclear. Hence, we performed this study to determine whether alcohol is a risk factor for mortality and fibrinolysis shutdown in trauma patients ...
Il-Jae Wang +11 more
doaj +1 more source