Results 91 to 100 of about 62,276 (286)

Poor glycemic control is independently associated with fibrinolysis shutdown in patients with peripheral artery disease

JVS - Vascular Science
Objective: Fibrinolysis plays a critical role in regulating thrombotic potential by facilitating the breakdown of fibrin-rich thrombi after clot formation.
Swechha Bhatt, MBBS, Aseman Bagheri Sheshdeh, BS, Shezan Fouzdar, MBBS, Radha Bansal, MBBS, Prajakta Lokhande, MBBS, Shanaya Vimadalal, BA, Shiv Patel, BA, Anahita Dua, MD, MBA, FACS   +7 more
doaj   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

SERPINE1 Alternative Polyadenylation Influences Gastric Cancer Prognosis via N6‐Methyladenosine Modification

Cancer Science, EarlyView.
Multi‐omics integration of the transcriptomic APA landscape and m6A modifications identifies key prognostic genes. Their biological functions and molecular mechanisms in promoting tumor progression are comprehensively validated through in vitro assays. ABSTRACT Alternative polyadenylation (APA) and N6‐methyladenosine (m6A) methylation are critical post‐
Zhuoyi Wu, Ruyun Xu, Ju Fang, Bing Liu, Cao Zhang, Shangxin Zhang, Jing Ni   +6 more
wiley   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

European Journal of Haematology, EarlyView.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto, Silvia Sorella, Erminia Baldacci, Massimo Breccia, Sabina Chiaretti, Marcello Capriata, Livia Donzelli, Gianna Maria D'Elia, Salvatore Giacomo Morano, Ilaria Del Giudice, Maurizio Martelli, Cristina Santoro, Antonio Chistolini   +12 more
wiley   +1 more source

Extent of peritoneal metastases from colorectal cancer is not associated with changes in thrombin generation or fibrinolysis

Pleura and Peritoneum
Cancer cells can activate coagulation and inhibit fibrinolysis. The aim was to investigate the association between the burden of peritoneal metastases from colorectal cancer (PM-CRC) and biomarkers reflecting thrombin generation and fibrinolysis.
Lundbech Mikkel, Krag Andreas Engel, Iversen Lene Hjerrild, Brandsborg Birgitte, Hvas Anne-Mette   +4 more
doaj   +1 more source

Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria

Allergy, Asthma & Clinical Immunology, 2018
Background Chronic spontaneous urticaria (CSU) is associated with activation of systemic inflammatory response and coagulation/fibrinolysis. Aim To study whether there is a relationship between the acute phase response and coagulation/fibrinolysis in ...
R. Grzanka, A. Damasiewicz-Bodzek, A. Kasperska-Zajac   +2 more
doaj   +1 more source

Fibrinolysis: Relative Effect of Inhibitors

, 2017
The process of fibrinolysis succeeds clot formation in blood plasma. It is imperative that both the complementary processes of clot formation and lysis occur in a regulated manner in order to maintain the integrity of the human vasculature.
Mohan, Anand, Susree, Modepalli
core  

Thrombotic Microangiopathy‐Like Phenotype in Patients With Infection‐Associated Disseminated Intravascular Coagulation Treated With Thrombomodulin Alfa

European Journal of Haematology, EarlyView.
ABSTRACT Despite disseminated intravascular coagulation (DIC) and thrombotic microangiopathy (TMA) sharing features of thrombocytopenia, organ dysfunction, and bleeding, the relationship between these two conditions remains unclear. We therefore conducted a post hoc analysis of post‐marketing surveillance data from Japan to evaluate the clinical ...
Naoki Takezako, Fumiyo Komatsu, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Kazuo Kawasugi, Seiji Madoiwa, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Kohji Okamoto, Hideo Wada   +11 more
wiley   +1 more source

Fibrinolysis and proteolysis.

Voortzetting van: Fibrinolysis: an international journal of fibrinolysis and ...
International society for fibrinolysis and thrombolysis
core  

Lifestyle, fibrinolysis and lipids

, 1997
Lifestyle including eating habits, physical training, smoking, drinking alcoholic beverages etc. can to a certain extent maintain or spoil our health.
Brommer, E.J.P., Brakman, P., Gevers Leuven, J.A.   +2 more
core