Results 111 to 120 of about 47,940 (267)
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, EarlyView.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Enhanced Fibrinolysis with Magnetically Powered Colloidal Microwheels
Small, 2017 Thrombi that occlude blood vessels can be resolved with fibrinolytic agents that degrade fibrin, the polymer that forms between and around platelets to provide mechanical stability.
T. Tasci +6 more
semanticscholar +1 more source
Journal of Thrombosis and Haemostasis, 2005 Chemicals / CAS: blood clotting factor 7a, 98982-74-2; bradykinin, 58-82-2, 5979-11-3; calcium, 7440-70-2; cyclic AMP, 60-92-4; desmopressin, 16679-58-6; fibrin, 9001-31-4; thrombin, 9002-04-4; tissue plasminogen activator, 105913-11-9; vasopressin, 11000-17-2; Tissue Plasminogen Activator, EC 3.4.21 ...
openaire +3 more sources
The fibrinolytic response to acute resistance training in lean and obese women
, 2007 Fibrinolysis is the process by which fibrin blood clots are dissolved. Fibrinolytic research is clinically relevant because decreased fibrinolytic potential is linked to increased risk of an ischemic event.
Pfeiffer, Rebecca L.
core
The FEBS Journal, EarlyView.Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre +2 more
wiley +1 more source
Scientific ReportsGlobal fibrinolysis assays detect the fibrinolysis time of clot dissolution using tissue-type plasminogen activator (tPA). Two such assays, clot-fibrinolysis waveform analysis (CFWA) and global fibrinolysis capacity (GFC) assay, were recently developed ...
Takumi Tsuchida +2 more
doaj +1 more source
Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria
Allergy, Asthma & Clinical Immunology, 2018 Background Chronic spontaneous urticaria (CSU) is associated with activation of systemic inflammatory response and coagulation/fibrinolysis. Aim To study whether there is a relationship between the acute phase response and coagulation/fibrinolysis in ...
R. Grzanka +2 more
doaj +1 more source
Fibrinolysis: from blood to the brain
Journal of Thrombosis and Haemostasis, 2017 We all know about classical fibrinolysis, how plasminogen activation by either tissue‐type plasminogen activator (t‐PA) or urokinase‐type plasminogen activator (u‐PA) promotes fibrin breakdown, and how this process was harnessed for the therapeutic ...
R. Medcalf
semanticscholar +1 more source
Risk Factors for Mortality in Dengue Shock Syndrome (DSS) [PDF]
, 2009 Background: Dengue shock syndrome (DSS) is the most severe form of dengue hemorrhagic fever (DHF) and has a high mortality. There are two major pathological changes in DHF determining the severity of disease, plasma leakage and bleeding.
Djokomoeljanto, Robert J +6 more
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Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community
Haemophilia, EarlyView.ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein +6 more
wiley +1 more source