Results 101 to 110 of about 80,628 (257)

Basic mechanisms and regulation of fibrinolysis

open access: yesJournal of Thrombosis and Haemostasis, 2015
Fibrinolysis appears in many diverse physiological situations, and the components of the system are well established, along with mechanistic details for the individual reactions and some high‐resolution structures.
C. Longstaff, K. Kolev
semanticscholar   +1 more source

Isogenic Transplantation of Hybrid Artificial Pleural Tissue Consisting of Rat Cells and Polyglycolic Acid Nanofiber Sheet Induces Restoration of Mesothelial Defects in Rat Model

open access: yesArtificial Organs, EarlyView.
We have successfully constructed hybrid 3D tissue using mesothelial cells, fibronectin‐gelatin nanofilm‐coated fibroblasts, and collagen‐coated PGA nanofiber sheets to create artificial pleura, and achieved successful isogenic engraftment in a rat model of pleural defects. ABSTRACT Background Impairment of the visceral pleura following thoracic surgery
Kengo Tani   +5 more
wiley   +1 more source

Management of pediatric pleural empyema: a national survey of pediatric surgeons in Brazil [PDF]

open access: yesJornal Brasileiro de Pneumologia
Objective: To identify how pediatric surgeons manage children with pneumonia and parapneumonic pleural effusion in Brazil. Methods: An online cross-sectional survey with 27 questions was applied to pediatric surgeons in Brazil through the Brazilian ...
Felippe Flausino   +4 more
doaj   +1 more source

Platelet-Mediated Modulation of Fibrinolysis

open access: yesSeminars in Thrombosis and Hemostasis, 2017
Platelets are crucial to the hemostatic response. Their role in coagulation is well documented and they have been considered for some time to promote resistance of thrombi to fibrinolysis. Platelets confer resistance to lysis by promoting clot retraction
Claire S. Whyte   +2 more
semanticscholar   +1 more source

Perioperative Mechanical Circulatory Support for Cardiac Assistance in Thoracic Surgery: A Scoping Review

open access: yesArtificial Organs, EarlyView.
High‐risk cardiac patients may benefit from timely temporary mechanical circulatory support (tMCS) implantation to provide perioperative hemodynamic stabilization and circulatory support, thus enabling them to undergo life‐saving thoracic surgery. CPB: cardiopulmonary bypass; IABP: intra‐aortic balloon pump; tMCS: temporary mechanical circulatory ...
Viviana Teresa Agosta   +4 more
wiley   +1 more source

Inhibition of Fibrinolysis by Coagulation Factor XIII

open access: yesBioMed Research International, 2017
The inhibitory effect of coagulation factor XIII (FXIII) on fibrinolysis has been studied for at least 50 years. Our insight into the underlying mechanisms has improved considerably, aided in particular by the discovery that activated FXIII cross-links ...
D. Rijken, S. Uitte de Willige
semanticscholar   +1 more source

Permeable Lung Vasculature Creates Chemoresistant Endothelial Niche by Producing SERPINE1 at Breast Cancer Metastatic Sites

open access: yesCancer Science, EarlyView.
Vascular permeability is increased by lung metastasis, which correlates with YAP activation in ECs. Activated ECs provide SERPINE1 to neighboring cancer cells to promote chemoresistance and stemness. ABSTRACT Chemotherapy resistance remains a major obstacle for eradicating metastatic cancer cells in distant organs. We identified that endothelial cells (
Tsunaki Hongu   +7 more
wiley   +1 more source

Fibrinolysis Shutdown Correlation with Thromboembolic Events in Severe COVID-19 Infection

open access: yesJournal of the American College of Surgeons, 2020
F. Wright   +8 more
semanticscholar   +1 more source

Circadian misalignment disrupts biomarkers of cardiovascular disease risk and promotes a hypercoagulable state

open access: yesEuropean Journal of Neuroscience, Volume 60, Issue 7, Page 5450-5466, October 2024.
We studied the impact of circadian misalignment on 238 plasma proteins linked to cardiovascular physiology. We identified 42 proteins with altered abundance, five proteins regulated by the circadian clock, and changes in many proteins in the coagulation pathway.
Andrew W. McHill   +3 more
wiley   +1 more source

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