Results 101 to 110 of about 101,683 (273)

Impaired Whole-Blood Fibrinolysis is a Predictor of Mortality in Intensive Care Patients

open access: yesTH Open
Background Altered fibrinolysis is considered to play a crucial role in the development of coagulopathy in sepsis. However, routine laboratory tests for fibrinolysis are currently very limited, and the impact of fibrinolytic capacity on ...
Julie S. Brewer   +3 more
doaj   +1 more source

Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim   +3 more
wiley   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

open access: yesPeriodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer   +4 more
wiley   +1 more source

Needle of Death Thromboelastography Tracings in Severely Bleeding Trauma Patients: A Novel Predictor of Hemorrhagic Blood Failure and Futile Resuscitation?

open access: yes
Academic Emergency Medicine, EarlyView.
Connor M. Bunch   +9 more
wiley   +1 more source

Tranexamic acid dosing in pediatric trauma: Dose simulation based on population pharmacokinetic modeling in adult trauma patients

open access: yesTransfusion, EarlyView.
Abstract Background Trauma is the most common cause of death in children >1 year of age, with hemorrhage being the most common preventable cause of death after injury. Antifibrinolytics like tranexamic acid (TXA) are a key aspect of trauma management in children, but optimal dosing remains unknown.
Gideon Stitt   +5 more
wiley   +1 more source

Clinical outcomes of patients with diabetes mellitus and acute myocardial infarction treated with primary angioplasty or fibrinolysis [PDF]

open access: bronze, 2002
Li‐Fern Hsu   +10 more
openalex   +1 more source

Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy

open access: yesTransfusion, EarlyView.
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna   +7 more
wiley   +1 more source

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