Results 111 to 120 of about 131,232 (324)

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Internal fibrinolysis of fibrin clots is driven by pore expansion

Scientific Reports
Blood clots, which are composed of blood cells and a stabilizing mesh of fibrin fibers, are critical in cessation of bleeding following injury. However, their action is transient and after performing their physiological function they must be resolved ...
Rebecca A. Risman, Bradley Paynter, Victoria Percoco, Mitali Shroff, Brittany E. Bannish, Valerie Tutwiler   +5 more
doaj   +1 more source

A Retrospective Study of Adult and Pediatric D‐Dimer Tests to Identify Opportunities for Improved Utilization

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction D‐dimers are produced by lysis of cross‐linked fibrin. In children, D‐dimer testing is used to evaluate disseminated intravascular coagulation (DIC) and some inflammatory states, but its use is not validated for screening or ruling out suspected venous thromboembolic events (VTE).
Rabab Al Dawood, Hassan Abu Sabah, Natalie Mathews, James Douketis, Catherine Hayward   +4 more
wiley   +1 more source

Comparison of results obtained using clot-fibrinolysis waveform analysis and global fibrinolysis capacity assay with rotational thromboelastography

Scientific Reports
Global fibrinolysis assays detect the fibrinolysis time of clot dissolution using tissue-type plasminogen activator (tPA). Two such assays, clot-fibrinolysis waveform analysis (CFWA) and global fibrinolysis capacity (GFC) assay, were recently developed ...
Takumi Tsuchida, Mineji Hayakawa, Osamu Kumano   +2 more
doaj   +1 more source

Massive Bleeding as the First Clinical Manifestation of Metastatic Prostate Cancer due to Disseminated Intravascular Coagulation with Enhanced Fibrinolysis

Case Reports in Hematology, 2016
Disseminated intravascular coagulation (DIC) is the most frequent coagulation disorder associated with metastatic prostate adenocarcinoma. However, DIC with enhanced fibrinolysis as an initial presentation of prostate cancer is extremely rare.
Mónica Palma Anselmo, Gustavo Nobre de Jesus, João Madeira Lopes, Rui M. M. Victorino, João Meneses Santos   +4 more
doaj   +1 more source

Intrathecal Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage: Evidence From Randomized Controlled Trials and Cohort Studies

Frontiers in Neurology, 2019
Background: The role of intrathecal fibrinolysis for the treatment of patients with aneurysmal subarachnoid hemorrhage (aSAH) has been widely investigated; however, the results have been contradictory.
Xiaocheng Lu, Chengyuan Ji, Jiang Wu, Wanchun You, Wei Wang, Zhong Wang, Gang Chen   +6 more
doaj   +1 more source

Out With the Old, in With the New: Age‐Related D‐Dimer Thresholds

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background A fixed D‐dimer cut‐off threshold of 0.500 μg/mL is used in Blackrock Health Hermitage Clinic (BHHC) and most Haematology laboratories across Ireland, however, international guidelines have evolved over the past decade, and a growing body of evidence supports the use of age‐adjusted D‐dimer thresholds.
Ciara O'Connor, Claire McIntyre, Claire Wynne   +2 more
wiley   +1 more source

Global Thrombosis Test - a possible monitoring system for the effects and safety of dabigatran [PDF]

, 2015
© Otsui et al. 2015BACKGROUND: Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not required; however, a
Gorog, Diana A, Inoue, Nobutaka, Iwata, Sachiyo, Otsui, Kazunori, Ozawa, Toru, Suzuki, Atsushi, Takei, Asumi, Yamamoto, Junichiro, Yoshioka, Takayuki   +8 more
core   +2 more sources

Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures

Journal of Periodontal Research, EarlyView.
Gingival recessions treated with a collagen matrix loaded with rhPDGF showed significantly greater early tissue perfusion compared to sites treated without the growth factor. Early tissue perfusion outcomes were correlated to the amount of root coverage and gingival thickness gain at 6 months.
Lorenzo Tavelli, Tu Nguyen, Maria Vera Rodriguez, Leonardo Mancini, William V. Giannobile, Shayan Barootchi   +5 more
wiley   +1 more source

Extent of peritoneal metastases from colorectal cancer is not associated with changes in thrombin generation or fibrinolysis

Pleura and Peritoneum
Cancer cells can activate coagulation and inhibit fibrinolysis. The aim was to investigate the association between the burden of peritoneal metastases from colorectal cancer (PM-CRC) and biomarkers reflecting thrombin generation and fibrinolysis.
Lundbech Mikkel, Krag Andreas Engel, Iversen Lene Hjerrild, Brandsborg Birgitte, Hvas Anne-Mette   +4 more
doaj   +1 more source