Results 111 to 120 of about 80,628 (257)

FIBRINOLYSIS. ITS MECHANISM AND SIGNIFICANCE [PDF]

, 1948
Robert Macfarlane, Rosemary Biggs
openalex   +1 more source

Structure‐function relationships in thrombin‐activatable fibrinolysis inhibitor

Journal of Thrombosis and Haemostasis, 2016
Thrombin‐activatable fibrinolysis inhibitor (TAFI) is an important regulator in the balance of coagulation and fibrinolysis. TAFI is a metallocarboxypeptidase that circulates in plasma as zymogen.
T. Plug, Joost C. M. Meijers
semanticscholar   +1 more source

Safety and Efficacy of Long‐Term Treatment of Type 1 Plasminogen Deficient Patients With Intravenous Plasminogen Replacement Therapy

Haemophilia, EarlyView.
ABSTRACT Introduction Type 1 plasminogen deficiency (PLGD‐1), or hypoplasminogenaemia, is an ultra‐rare autosomal‐recessive disorder characterised by fibrin‐rich lesions on mucous membranes, often leading to serious complications if left untreated. Prior treatments have shown limited and inconsistent success, but IV PLG concentrate (Ryplazim) offers a ...
Amy D. Shapiro, Heather McDaniel, Robert W. Decker, Charles Nakar, Jeremy Lorber, Neelam Thukral, Joseph M. Parker, Karen Thibaudeau   +7 more
wiley   +1 more source

Inhibition of Fibrinolysis in vivo by feeding Cholesterol [PDF]

, 1957
Hau C. Kwaan, A. J. S. McFadzean
openalex   +1 more source

Impaired Whole-Blood Fibrinolysis is a Predictor of Mortality in Intensive Care Patients

TH Open
Background Altered fibrinolysis is considered to play a crucial role in the development of coagulopathy in sepsis. However, routine laboratory tests for fibrinolysis are currently very limited, and the impact of fibrinolytic capacity on ...
Julie S. Brewer, Christine L. Hvas, Anne-Mette Hvas, Julie B. Larsen   +3 more
doaj   +1 more source

The Mechanism of Fibrinolysis Induced by Bacterial Pyrogens [PDF]

, 1959
Éric Deutsch, P. Elsner, Ian C. Marschner   +2 more
openalex   +1 more source

Early ST elevation myocardial infarction in non-capable percutaneous coronary intervention centres: in situ fibrinolysis vs. percutaneous coronary intervention transfer.

European Heart Journal, 2016
AIMS The preferred reperfusion strategy for early ST elevation myocardial infarction (STEMI, defined as time from symptoms onset ≤120 min) in non-capable percutaneous coronary intervention (PCI) centres remains controversial.
X. Carrillo, E. Fernández-Nofrerías, O. Rodriguez-Leor, T. Oliveras, J. Serra, J. Mauri, A. Curós, F. Rueda, C. García-García, R. Tresserras, Alba Rosas, M. Faixedas, A. Bayés‐Genís   +12 more
semanticscholar   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur, Christopher Dowson, Susan M. Bissett, Rachel van de Merwe, John J. Taylor, Philip M. Preshaw, Katrin M. Jaedicke   +6 more
wiley   +1 more source

STUDIES OF STREPTOCOCCAL FIBRINOLYSIS. III. A QUANTITATIVE METHOD FOR THE ESTIMATION OF SERUM ANTIFIBRINOLYSIN 1 [PDF]

, 1946
Melvin H. Kaplan
openalex   +1 more source

Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin

Journal of Trauma and Acute Care Surgery, 2017
BACKGROUND A subset of trauma patients undergo fibrinolysis shutdown rather than pathologic hyperfibrinolysis, contributing to organ failure. The molecular basis for fibrinolysis shutdown in trauma is incompletely understood.
Christopher D. Barrett, H. Moore, A. Banerjee, C. Silliman, E. Moore, M. Yaffe   +5 more
semanticscholar   +1 more source