Results 11 to 20 of about 131,232 (324)

Annexin A2 in Fibrinolysis, Inflammation and Fibrosis

International Journal of Molecular Sciences, 2021
As a cell surface tissue plasminogen activator (tPA)-plasminogen receptor, the annexin A2 (A2) complex facilitates plasmin generation on the endothelial cell surface, and is an established regulator of hemostasis.
Hana I Lim, K. Hajjar
semanticscholar   +1 more source

Fibrinolytic therapy use for ST-segment elevation myocardial infarction and long-term outcomes in China: 2-year results from the China Acute Myocardial Infarction Registry

BMC Cardiovascular Disorders, 2023
Background Data on fibrinolytic therapy use for ST-segment elevation myocardial infarction (STEMI) and long-term clinical outcomes in developing countries are limited.
Chao Wu, Ling Li, Shuqing Wang, Jianping Zeng, Jingang Yang, Haiyan Xu, Yanyan Zhao, Yang Wang, Wei Li, Chen Jin, Xiaojin Gao, Yuejin Yang, Shubin Qiao   +12 more
doaj   +1 more source

Point-of-care diagnosis and monitoring of fibrinolysis resistance in the critically ill: results from a feasibility study

Critical Care, 2023
Background Fibrinolysisis is essential for vascular blood flow maintenance and is triggered by endothelial and platelet release of tissue plasminogen activator (t-PA). In certain critical conditions, e.g.
Lucy A. Coupland, David J. Rabbolini, Jonathan G. Schoenecker, Philip J. Crispin, Jennene J. Miller, Tony Ghent, Robert L. Medcalf, Anders E. Aneman   +7 more
doaj   +1 more source

uPA-mediated plasminogen activation is enhanced by polyphosphate

Haematologica, 2020
Tissue plasminogen activator (tPA) and urokinase (uPA) differ in their modes of action. Efficient tPA-mediated plasminogen activation requires binding to fibrin.
Claire S. Whyte, Nicola J. Mutch
doaj   +1 more source

Microparticles and Fibrinolysis [PDF]

Seminars in Thrombosis and Hemostasis, 2016
Microparticles (MPs) are submicronic vesicles which are formed by budding of the cellular membrane of virtually any cell type in response to cell activation or apoptosis. Both circulating MPs and MPs generated within tissues harbor molecules with a large repertoire of biological activities and transfer material to target cells.
Vallier, Loris, Cointe, Sylvie, Lacroix, Romaric, Bonifay, Amandine, Judicone, Coralie, Dignat-George, Francoise, Kwaan, Hau C   +6 more
openaire   +2 more sources

Assessment of Fibrinolysis in Sepsis Patients with Urokinase Modified Thromboelastography. [PDF]

PLoS ONE, 2015
Impairment of fibrinolysis during sepsis is associated with worse outcome. Early identification of this condition could be of interest. The aim of this study was to evaluate whether a modified point-of-care viscoelastic hemostatic assay can detect sepsis-
Mauro Panigada, Lucia Zacchetti, Camilla L'Acqua, Massimo Cressoni, Massimo Boscolo Anzoletti, Rossella Bader, Alessandro Protti, Dario Consonni, Armando D'Angelo, Luciano Gattinoni   +9 more
doaj   +1 more source

The state of the fibrinolytic system in HIV-infected pregnant women and parturient women with thrombohemorrhagic risk factors

Репродуктивная эндокринология, 2020
Purpose of the study: to explore the status of the fibrinolytic system in HIV-infected pregnant women and parturient women. Materials and methods. 120 HIV-positive pregnant women with risk factors of thrombohemorrhagic complications were examined.
С. Є. Савченко, О. І. Гервазюк, Л. М. Онищик, Ю. С. Мудра, Г. Б. Бойко   +4 more
doaj   +1 more source

Increased thrombin activatable fibrinolysis inhibitor activity is associated with hypofibrinolysis in dogs with sepsis

Frontiers in Veterinary Science, 2023
IntroductionDisorders of coagulation are well-recognized in dogs with sepsis, but data regarding fibrinolysis disorders are limited. We aimed to characterize fibrinolysis in dogs with sepsis compared to healthy controls.
Katherine E. Sotos, Robert Goggs, Alyssa P. Stablein, Marjory B. Brooks   +3 more
doaj   +1 more source

Fibrinolysis Shutdown and Thrombosis in A COVID-19 ICU.

Shock, 2020
The coronavirus disease (COVID-19) pandemic has threatened millions of lives worldwide with severe systemic inflammation, organ dysfunction, and thromboembolic disease. Within our institution, many critically ill COVID-19 positive patients suffered major
Christina Creel-Bulos, S. Auld, Mark E Caridi-Scheible, Nicholas A. Barker, Sarah Friend, M. Gaddh, C. Kempton, C. Maier, Fadi Nahab, Roman M. Sniecinski   +9 more
semanticscholar   +1 more source

Endogenous fibrinolysis inhibitors in acute coronary syndrome

American Heart Journal Plus, 2021
Patients with acute coronary syndrome have a high residual risk of ischemic events despite current treatment methods, both invasive and antithrombotic strategies. The strategy of very early revascularization although has been suggested to improve patient
Baskaran Chandrasekar
doaj   +1 more source