Results 21 to 30 of about 101,683 (273)

Assessment of Fibrinolysis in Sepsis Patients with Urokinase Modified Thromboelastography. [PDF]

PLoS ONE, 2015
Impairment of fibrinolysis during sepsis is associated with worse outcome. Early identification of this condition could be of interest. The aim of this study was to evaluate whether a modified point-of-care viscoelastic hemostatic assay can detect sepsis-
Mauro Panigada, Lucia Zacchetti, Camilla L'Acqua, Massimo Cressoni, Massimo Boscolo Anzoletti, Rossella Bader, Alessandro Protti, Dario Consonni, Armando D'Angelo, Luciano Gattinoni   +9 more
doaj   +1 more source

The state of the fibrinolytic system in HIV-infected pregnant women and parturient women with thrombohemorrhagic risk factors

Репродуктивная эндокринология, 2020
Purpose of the study: to explore the status of the fibrinolytic system in HIV-infected pregnant women and parturient women. Materials and methods. 120 HIV-positive pregnant women with risk factors of thrombohemorrhagic complications were examined.
С. Є. Савченко, О. І. Гервазюк, Л. М. Онищик, Ю. С. Мудра, Г. Б. Бойко   +4 more
doaj   +1 more source

Endogenous fibrinolysis inhibitors in acute coronary syndrome

American Heart Journal Plus, 2021
Patients with acute coronary syndrome have a high residual risk of ischemic events despite current treatment methods, both invasive and antithrombotic strategies. The strategy of very early revascularization although has been suggested to improve patient
Baskaran Chandrasekar
doaj   +1 more source

Increased thrombin activatable fibrinolysis inhibitor activity is associated with hypofibrinolysis in dogs with sepsis

Frontiers in Veterinary Science, 2023
IntroductionDisorders of coagulation are well-recognized in dogs with sepsis, but data regarding fibrinolysis disorders are limited. We aimed to characterize fibrinolysis in dogs with sepsis compared to healthy controls.
Katherine E. Sotos, Robert Goggs, Alyssa P. Stablein, Marjory B. Brooks   +3 more
doaj   +1 more source

Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation [PDF]

, 2019
© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which ...
Arachchillage, Deepa RJ, Farag, Mohamed, Gorog, Diana, Gue, Ying X., Lip, Gregory Y H, Spinthakis, Nikolaos, Srinivasan, Manivannan, Wellsted, David   +7 more
core   +3 more sources

Rationale and design of "Can Very Low Dose Rivaroxaban (VLDR) in addition to dual antiplatelet therapy improve thrombotic status in acute coronary syndrome (VaLiDate-R)" study : A randomised trial modulating endogenous fibrinolysis in patients with acute coronary syndrome [PDF]

, 2019
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
Gorog, Diana A, Gue, Ying X, Kanji, Rahim, Srinivasan, Manivannan, Wellsted, David M, Wyatt, Solange   +5 more
core   +2 more sources

Impaired endogenous fibrinolysis at high shear using a point-of-care test in STEMI is associated with alterations in clot architecture [PDF]

, 2019
© The Author(s) 2019Impaired endogenous fibrinolysis is an adverse prognostic biomarker in acute coronary syndrome (ACS). Abnormally dense in vitro fibrin thrombi have been demonstrated in ACS patients and related to hypofibrinolysis using cumbersome ...
A Undas, Anwar Baydoun, C Christopoulos, DB Cines, Diana A. Gorog, Guogang Ren, Manivannan Srinivasan, Mohamed Farag, Nikolaos Spinthakis, ON Okafor, S Saraf, W Sumaya, Ying Gue   +12 more
core   +3 more sources

Enhanced fibrinolysis detection in a natural occurring canine model with intracavitary effusions: Comparison and degree of agreement between thromboelastometry and FDPs, D-dimer and fibrinogen concentrations.

PLoS ONE, 2019
Dogs with intracavitary effusion have coagulative abnormalities indicative of primary fibrinolysis/hyperfibrinolysis. The aim of this case control study was to investigate by rotational thromboelastometry (ROTEM) and standard coagulation tests (fibrin ...
Andrea Zoia, Michele Drigo, Christine J Piek, Helena Calcini, Marco Caldin, Paolo Simioni   +5 more
doaj   +1 more source

Tissue factor-expressing monocytes inhibit fibrinolysis through a TAFI-mediated mechanism, and make clots resistant to heparins

Haematologica, 2009
Background Thrombin is the main activator of the fibrinolysis inhibitor TAFI (thrombin activatable fibrinolysis inhibitor) and heightened clotting activation is believed to impair fibrinolysis through the increase of thrombin activatable fibrinolysis ...
Fabrizio Semeraro, Concetta T. Ammollo, Nicola Semeraro, Mario Colucci   +3 more
doaj   +1 more source

Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration. [PDF]

, 2020
OBJECTIVE: To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women. METHODS: We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered
Arulkumaran, S, Balakumar, S, Muhunthan, K, Navaratnaraja, TS, Premakrishna, S   +4 more
core   +1 more source