Impaired endogenous fibrinolysis at high shear using a point-of-care test in STEMI is associated with alterations in clot architecture [PDF]
, 2019 © The Author(s) 2019Impaired endogenous fibrinolysis is an adverse prognostic biomarker in acute coronary syndrome (ACS). Abnormally dense in vitro fibrin thrombi have been demonstrated in ACS patients and related to hypofibrinolysis using cumbersome ...
A Undas +12 more
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Hämostaseologie, 2021 AbstractPhysiological fibrinolysis under normal conditions progresses slowly, in contrast to coagulation which is triggered rapidly to stop bleeding and defend against microbial invasion. Methods to detect fibrinolysis abnormalities are less simple and poorly standardized compared with common coagulation tests.
openaire +2 more sources
Fibrinolysis for patients with intermediate-risk pulmonary embolism.
New England Journal of Medicine, 2014 BACKGROUND The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial. METHODS In a randomized, double-blind trial, we compared tenecteplase plus heparin with placebo plus heparin in normotensive patients ...
G. Meyer +36 more
semanticscholar +1 more source
Journal of Clinical Medicine, 2020 Background: Coronavirus Disease 2019 (COVID-19)-associated coagulopathy is characterized by a prothrombotic state not yet comprehensively studied. We investigated the coagulation pattern of patients with COVID-19 acute respiratory distress syndrome (ARDS)
M. Ranucci +6 more
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Rationale and design of "Can Very Low Dose Rivaroxaban (VLDR) in addition to dual antiplatelet therapy improve thrombotic status in acute coronary syndrome (VaLiDate-R)" study : A randomised trial modulating endogenous fibrinolysis in patients with acute coronary syndrome [PDF]
, 2019 © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
Gorog, Diana A +5 more
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Clot formation and resolution properties of platelets during cold storage for 21 days. [PDF]
TransfusionAbstract Background Cold storage (2–6°C) preserves the aggregatory and clot formation properties of platelets beyond the standard 7‐day shelf life. Comparatively little is known about the effect of cold storage on clot resolution functions, which are necessary to ensure normal hemostatic balance is maintained.
Mahajan J +3 more
europepmc +2 more sources
Studies on an antifibrinolytic agent trans-AMCHA [PDF]
, 1968 Lysis of fibrin was first recognized by MORGAGNI in 1769, observing a liquid blood in a patient of acute death, and the phenomenon was named as fibrinolysis by DASTRE in 1893.
Fujiyama, Noboru +5 more
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Fibrinolysis and COVID‐19: A plasmin paradox
Journal of Thrombosis and Haemostasis, 2020 The COVID‐19 pandemic has provided many challenges in the field of thrombosis and hemostasis. Among these is a novel form of coagulopathy that includes exceptionally high levels of D‐dimer.
R. Medcalf +2 more
semanticscholar +1 more source
Haematologica, 2009 Background Thrombin is the main activator of the fibrinolysis inhibitor TAFI (thrombin activatable fibrinolysis inhibitor) and heightened clotting activation is believed to impair fibrinolysis through the increase of thrombin activatable fibrinolysis ...
Fabrizio Semeraro +3 more
doaj +1 more source
Endogenous Fibrinolysis : An Important Mediator of Thrombus Formation and Cardiovascular Risk [PDF]
, 2015 © 2015 BY THE AMERICAN COLLEGE OF CARDIOLOGY FOUNDATION. PUBLISHED BY ELSEVIER INC.Most acute cardiovascular events are attributable to arterial thrombosis.
Gorog, Diana A, Okafor, Osita N
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