Results 21 to 30 of about 80,628 (257)

Tissue factor-expressing monocytes inhibit fibrinolysis through a TAFI-mediated mechanism, and make clots resistant to heparins

Haematologica, 2009
Background Thrombin is the main activator of the fibrinolysis inhibitor TAFI (thrombin activatable fibrinolysis inhibitor) and heightened clotting activation is believed to impair fibrinolysis through the increase of thrombin activatable fibrinolysis ...
Fabrizio Semeraro, Concetta T. Ammollo, Nicola Semeraro, Mario Colucci   +3 more
doaj   +1 more source

Fibrinolysis and COVID‐19: A plasmin paradox

Journal of Thrombosis and Haemostasis, 2020
The COVID‐19 pandemic has provided many challenges in the field of thrombosis and hemostasis. Among these is a novel form of coagulopathy that includes exceptionally high levels of D‐dimer.
R. Medcalf, Charithani B. Keragala, P. Myles   +2 more
semanticscholar   +1 more source

Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

Annals of Intensive Care, 2019
BackgroundSeptic coagulopathy represents a very dynamic disease entity, tilting from initial hypercoagulability towards a subsequent hypocoagulable disease state, entitled overt disseminated intravascular coagulation.
F. Schmitt, V. Manolov, Jakob Morgenstern, T. Fleming, S. Heitmeier, F. Uhle, M. Al-Saeedi, T. Hackert, T. Bruckner, H. Schöchl, M. Weigand, S. Hofer, T. Brenner   +12 more
semanticscholar   +1 more source

SARS‐CoV‐2 infection of companion animals in Egypt and its risk of spillover

Veterinary Medicine and Science, Volume 9, Issue 1, Page 13-24, January 2023., 2023
Graphical abstract depicts SARS‐CoV‐2 spillover in humans and their pet animals with common symptoms. Besides, it illustrates number of SARS‐CoV‐2‐infected cats and dogs with severity of respiratory signs. Abstract Background Reverse zoonoses occur because of interactions between humans and animals.
Mervat E. Hamdy, Ayman H. El‐Deeb, Naglaa M. Hagag, Momtaz A. Shahein, Namal P. M. Liyanage, Mohamed Shalaan, Hussein A. Hussein   +6 more
wiley   +1 more source

Enhanced fibrinolysis detection in a natural occurring canine model with intracavitary effusions: Comparison and degree of agreement between thromboelastometry and FDPs, D-dimer and fibrinogen concentrations.

PLoS ONE, 2019
Dogs with intracavitary effusion have coagulative abnormalities indicative of primary fibrinolysis/hyperfibrinolysis. The aim of this case control study was to investigate by rotational thromboelastometry (ROTEM) and standard coagulation tests (fibrin ...
Andrea Zoia, Michele Drigo, Christine J Piek, Helena Calcini, Marco Caldin, Paolo Simioni   +5 more
doaj   +1 more source

Relationship Between Severity of Fibrinolysis Based on Rotational Thromboelastometry and Conventional Fibrinolysis Markers

Clinical and Applied Thrombosis/Hemostasis, 2020
The association between severity of fibrinolysis, ascertained by rotational thromboelastometry to diagnose hyperfibrinolysis in patients with out-of-hospital cardiac arrest (OHCA), and conventional fibrinolysis markers (ie, tissue-plasminogen activator ...
Tomoyo Saito MD, PhD, Mineji Hayakawa MD, PhD, Yoshinori Honma MD, Asumi Mizugaki MD, Tomonao Yoshida MD, Kenichi Katabami MD, Takeshi Wada MD, PhD, Kunihiko Maekawa MD   +7 more
doaj   +1 more source

Fibrin Breakdown Assay

Bio-Protocol, 2020
Fibrinolysis is an integral part of the matrix remodeling process that contributes to tissue repair. Fibrin clots are broken down during fibrinolysis in a controlled process.
Jiayue Ling, Connor Blair, George Baillie   +2 more
doaj   +1 more source

What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies

Blood Coagulation and Fibrinolysis, 2019
&NA; Intravenous tranexamic acid (TXA) reduces death because of bleeding in patients with trauma and postpartum haemorrhage. However, in some settings intravenous injection is not feasible.
R. Picetti, H. Shakur-Still, R. Medcalf, J. Standing, I. Roberts   +4 more
semanticscholar   +1 more source

Venous thromboembolism prophylaxis in pregnancy: Are we adequately identifying and managing risks?

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 62, Issue 6, Page 915-920, December 2022., 2022
Pregnancy is a well‐known risk factor of venous thromboembolism. We retrospectively reviewed case histories of 82 pregnant women who developed symptoms of venous pathology, thrombophlebitis, deep vein thrombosis (DVT) or pulmonary embolus (PE) while receiving care at our hospital.
Kay Rui Choy, Shannon Emmett, Audris Wong   +2 more
wiley   +1 more source

Fibrinolysis and Inflammation in Venous Thrombus Resolution

Frontiers in Immunology, 2019
Clinical observations and accumulating laboratory evidence support a complex interplay between coagulation, inflammation, innate immunity and fibrinolysis in venous thromboembolism (VTE).
S. Mukhopadhyay, Tierra A. Johnson, Nadire Duru, Marguerite S Buzza, Nisha R Pawar, R. Sarkar, T. Antalis   +6 more
semanticscholar   +1 more source