Results 31 to 40 of about 96,663 (275)

Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]

, 2018
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast, AD Michelson, B Labarthe, B Shen, C Patrono, CT Ammollo, D Capodanno, D Gailani, DA Gorog, Diana A. Gorog, DM Coenen, E Álvarez, ER Bates, F Kabirian, F Müller, F Semeraro, G Stephens, H Brogren, HE Speich, HE Speich, HJ Weiss, HJ Weiss, HR Baumgartner, J Zilberman-Rudenko, JD McFadyen, JI Weitz, JM Cosemans, JP Collet, JP Collet, K Hosokawa, K Nagatsuka, KS Sakariassen, L Valerio, LF Brass, M Cattaneo, M Farag, M Humbert, M Larsson, M Li, M Ungerer, MA Bailey, MI Furman, MJ Price, ML Montfoort von, MS Sabatine, P Andre, P Seizer, PA Borne von dem, PP Wadowski, R Hellmuth, R Nergiz-Unal, RA Ajjan, S Goto, S Goto, SA Shaya, SB Larsen, SJ Marciniak, T Heitzer, T Renné, VT Turitto, VT Turitto, WA Schumacher, WS Nesbitt, X Wang, Y Yano, YC Lau, ZM Ruggeri   +66 more
core   +2 more sources

Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration. [PDF]

, 2020
OBJECTIVE: To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women. METHODS: We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered
Arulkumaran, S, Balakumar, S, Muhunthan, K, Navaratnaraja, TS, Premakrishna, S   +4 more
core   +1 more source

Thrombin-anti-thrombin levels and patency of arterio-venous fistula in patients undergoing haemodialysis compared to healthy volunteers : a prospective analysis [PDF]

, 2013
Peer reviewedPublisher ...
Brittenden, Julie, Fluck, Nicholas, Ford, Isobel, Milburn, James, Mutch, Nicola J   +4 more
core   +6 more sources

Tissue factor-expressing monocytes inhibit fibrinolysis through a TAFI-mediated mechanism, and make clots resistant to heparins

Haematologica, 2009
Background Thrombin is the main activator of the fibrinolysis inhibitor TAFI (thrombin activatable fibrinolysis inhibitor) and heightened clotting activation is believed to impair fibrinolysis through the increase of thrombin activatable fibrinolysis ...
Fabrizio Semeraro, Concetta T. Ammollo, Nicola Semeraro, Mario Colucci   +3 more
doaj   +1 more source

Fibrin Breakdown Assay

Bio-Protocol, 2020
Fibrinolysis is an integral part of the matrix remodeling process that contributes to tissue repair. Fibrin clots are broken down during fibrinolysis in a controlled process.
Jiayue Ling, Connor Blair, George Baillie   +2 more
doaj   +1 more source

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Ammollo, Aziz, Borissoff, Brill, Brinkmann, Clark, Esmon, Esmon, Fuchs, Fuchs, Gladysheva, Gleber, Guthold, Komissarov, Komorowicz, Longstaff, Longstaff, Massberg, Nikolova, Rocha, Ruf, Ryan, Rábai, Rácz, Saha, Sands, Scrutton, Semeraro, Silva, Smeeth, Walker, Weisel, Weisel, Wohner, Xu, Yang, Yeromonahos   +36 more
core   +1 more source

Enhanced fibrinolysis detection in a natural occurring canine model with intracavitary effusions: Comparison and degree of agreement between thromboelastometry and FDPs, D-dimer and fibrinogen concentrations.

PLoS ONE, 2019
Dogs with intracavitary effusion have coagulative abnormalities indicative of primary fibrinolysis/hyperfibrinolysis. The aim of this case control study was to investigate by rotational thromboelastometry (ROTEM) and standard coagulation tests (fibrin ...
Andrea Zoia, Michele Drigo, Christine J Piek, Helena Calcini, Marco Caldin, Paolo Simioni   +5 more
doaj   +1 more source

Impaired endogenous fibrinolysis at high shear using a point-of-care test in STEMI is associated with alterations in clot architecture [PDF]

, 2019
© The Author(s) 2019Impaired endogenous fibrinolysis is an adverse prognostic biomarker in acute coronary syndrome (ACS). Abnormally dense in vitro fibrin thrombi have been demonstrated in ACS patients and related to hypofibrinolysis using cumbersome ...
A Undas, Anwar Baydoun, C Christopoulos, DB Cines, Diana A. Gorog, Guogang Ren, Manivannan Srinivasan, Mohamed Farag, Nikolaos Spinthakis, ON Okafor, S Saraf, W Sumaya, Ying Gue   +12 more
core   +3 more sources

Angiographic outcomes in STEMI patients receiving fibrinolysis with guideline directed optimal antithrombotic therapy

Indian Heart Journal, 2021
STEMI is a major public health problem requiring timely reperfusion. Fibrinolysis remains prevalent reperfusion strategy where timely primary percutaneous coronary intervention (PCI) cannot be performed.
Shazia Durdana, Mohammad Azharuddin Malik, Asif Hasan, M.U. Rabbani   +3 more
doaj   +1 more source

Relationship Between Severity of Fibrinolysis Based on Rotational Thromboelastometry and Conventional Fibrinolysis Markers

Clinical and Applied Thrombosis/Hemostasis, 2020
The association between severity of fibrinolysis, ascertained by rotational thromboelastometry to diagnose hyperfibrinolysis in patients with out-of-hospital cardiac arrest (OHCA), and conventional fibrinolysis markers (ie, tissue-plasminogen activator ...
Tomoyo Saito MD, PhD, Mineji Hayakawa MD, PhD, Yoshinori Honma MD, Asumi Mizugaki MD, Tomonao Yoshida MD, Kenichi Katabami MD, Takeshi Wada MD, PhD, Kunihiko Maekawa MD   +7 more
doaj   +1 more source