Results 71 to 80 of about 96,663 (275)

Quantification of antithrombin isoform proportions in plasma samples of healthy subjects, sepsis patients, and in antithrombin concentrates [PDF]

, 2002
Antithrombin (AT) circulates in plasma in two isoforms, AT-alpha (90-95%) and AT-beta (5-10%). AT isoform proportions were measured in plasma samples of 17 healthy subjects and 26 posttraumatic or postoperative septic patients, as well as in 4 ...
Donges, R., Hoffmann, J. N., Inthorn, D., Jochum, M., Muhlbayer, D., Romisch, J., Stauss, H.   +6 more
core   +1 more source

Site‐Specific Antithrombotic Therapy: 24‐Month Outcomes of the Randomized DESyne BDS Plus Trial Using a Novel Triple‐Drug Eluting Coronary Implant With Two Anticoagulants and Sirolimus

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background DESyne BDS Plus represents a novel triple drug therapy (TRx) applied on a coronary stent platform eluting the antiproliferative drug Sirolimus along with two anticoagulants (Rivaroxaban and Argatroban) to reduce the site‐specific thrombotic risk.
Stefan Verheye, Bert Ferdinande, Johan Bennett, Rodolfo Staico, Seif El‐Jack, Pim A. L. Tonino, Alexandre Abizaid, Ian Buysschaert, Douglas Scott, Madhav Menon, Gerard Wilkins, Dougal McClean, Tomas Kovarnik, Uwe Christians, Antoinette Neylon, Zlatko Mehmedbegovic, Pieter C. Smits, Marie‐Claude Morice, Mark Webster, the DESyne BDS Plus RCT Investigators   +19 more
wiley   +1 more source

The hyaluronan-binding serine protease from human plasma cleaves HMW and LMW kininogen and releases bradykinin [PDF]

, 2002
The influence of the hyaluronanbinding protease (PHBSP), a plasma enzyme with FVII- and pro-urokinase-activating potency, on components of the contact phase (kallikrein/kinin) system was investigated.
Beer, N., Dodt, J., Etscheid, M., Fink, E., Seitz, R.   +4 more
core   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Immuno‐haemostatic dysregulation in heart failure with preserved ejection fraction

ESC Heart Failure, EarlyView.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a complex condition with partially unclear pathophysiology, in which systemic inflammation is a central contributor to changes in cardiac structure and function. The contribution of non‐traditional immune effectors—such as platelets and coagulation—remains underexplored in HFpEF ...
Giorgia D'Italia, Daniëlle M. Coenen, Titus P. Lemmens, Lloyd Brandts, Simone J. H. Wielders, Magdolna Nagy, Sanne G. J. Mourmans, Anouk Achten, Ahmad Al‐Abadi, Jerremy Weerts, Arantxa Barandiaran Aizpurua, Vanessa van Empel, Blanche Schroen, Judith M. E. M. Cosemans   +13 more
wiley   +1 more source

Effects of moderate weight loss on anginal symptoms and indices of coagulation and fibrinolysis in overweight patients with angina pectoris [PDF]

, 2002
Objective: To evaluate the effects of moderate weight loss, in overweight patients with angina, on plasma coagulation, fibrinolytic indicies and pain frequency.
Hankey, C.R., Lean, M.E.J., Lowe, G.D.O., Rumley, A., Woodward, M.   +4 more
core   +1 more source

Protective effect of rooming‐in on postpartum hemorrhage: A propensity score analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study investigates the effect of rooming‐in on postpartum hemorrhage (PPH) and other adverse maternal postpartum outcomes. Methods A retrospective study was performed on all healthy women with singleton term pregnancies at a tertiary medical center between 2013 and 2022.
Natav Hendin, Yossi Geron, Ran Matot, Shiran Loewenstein, Eran Hadar, Asnat Walfisch, Rony Chen, Ohad Houri   +7 more
wiley   +1 more source

Abnormal plasma clot formation and fibrinolysis reveal bleeding tendency in patients with partial factor XI deficiency

Blood Advances, 2018
: Individuals with factor XI (FXI) deficiency have a variable bleeding risk that cannot be predicted from plasma FXI antigen or activity. This limitation can result in under- or overtreatment of patients and risk of bleeding or thrombosis.
Gillian N. Gidley, Lori A. Holle, John Burthem, Paula H.B. Bolton-Maggs, Feng-Chang Lin, Alisa S. Wolberg   +5 more
doaj   +1 more source

Medical treatment of fibroids: FIGO best practice guidance

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Even though uterine fibroids are a widespread condition, the range of approved medical treatment options remains limited. In fact, only a few drugs are officially approved for the therapy of fibroids. In both the USA and the European Medicines Agency region, selected gonadotropin‐releasing hormone (GnRH) antagonists have been approved for this
Ivonne Diaz, Mary Ann Lumsden, Magdalena Zeppernick   +2 more
wiley   +1 more source

Routine Laboratory Tests Predict 72‐h Fatality in Patients With D‐Dimer Levels ≥ 2 μg/mL: A Retrospective Cohort Study Comparing Statistical and Machine Learning Models

Journal of Clinical Laboratory Analysis, EarlyView.
This study compares multivariate logistic regression (MLRA) and four machine learning models in predicting 72‐h fatality in patients with D‐dimer levels ≥ 2 μg/mL. MLRA identified five significant factors: advanced age, low total protein and cholesterol levels, and high aspartate aminotransferase and D‐dimer levels.
Shuma Hayashi, Ryoko Hayashi, Kayoko Nakamura, Kai Saito, Hidenori Sanayama, Takahiko Fukuchi, Tamami Watanabe, Kiyoka Omoto, Hitoshi Sugawara   +8 more
wiley   +1 more source