Results 81 to 90 of about 80,628 (257)

Bleeding related to disturbed fibrinolysis

British Journal of Haematology, 2016
The components and reactions of the fibrinolysis system are well understood. The pathway has fewer reactants and interactions than coagulation, but the generation of a complete quantitative model is complicated by the need to work at the solid‐liquid ...
K. Kolev, C. Longstaff
semanticscholar   +1 more source

Livedoid Vasculopathy Successfully Treated With JAK Inhibitors

JEADV Clinical Practice, EarlyView.
ABSTRACT Livedoid vasculopathy is a rare thrombotic disease of the small blood vessels. It manifests as fixed violaceous macules, noninflammatory retiform purpura, painful ulcers, and white atrophic scars on the lower extremities. The pathophysiology involves the type 1 interferon pathway. Many patients do not improve with oral anticoagulants.
Antoine Delpuech, Emilie Tournier, Pierre Sohier, Nicolas Dupin, Chloe Challamel, Sara Altandi, Serge Boulinguez, Carle Paul   +7 more
wiley   +1 more source

Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria

Allergy, Asthma & Clinical Immunology, 2018
Background Chronic spontaneous urticaria (CSU) is associated with activation of systemic inflammatory response and coagulation/fibrinolysis. Aim To study whether there is a relationship between the acute phase response and coagulation/fibrinolysis in ...
R. Grzanka, A. Damasiewicz-Bodzek, A. Kasperska-Zajac   +2 more
doaj   +1 more source

Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.

New England Journal of Medicine, 2013
BACKGROUND It is not known whether prehospital fibrinolysis, coupled with timely coronary angiography, provides a clinical outcome similar to that with primary percutaneous coronary intervention (PCI) early after acute ST-segment elevation myocardial ...
P. Armstrong, A. Gershlick, P. Goldstein, R. Wilcox, T. Danays, Y. Lambert, V. Sulimov, F. Rosell Ortiz, M. Ostojić, R. Welsh, A. Carvalho, J. Nanas, H. Arntz, S. Halvorsen, K. Huber, S. Grajek, C. Fresco, E. Bluhmki, Anne Regelin, K. Vandenberghe, K. Bogaerts, F. Van de Werf   +21 more
semanticscholar   +1 more source

Fibrinolysis: from blood to the brain

Journal of Thrombosis and Haemostasis, 2017
We all know about classical fibrinolysis, how plasminogen activation by either tissue‐type plasminogen activator (t‐PA) or urokinase‐type plasminogen activator (u‐PA) promotes fibrin breakdown, and how this process was harnessed for the therapeutic ...
R. Medcalf
semanticscholar   +1 more source

Enhancing Hemocompatibility in ECMO Systems With a Fibrinolytic Interactive Coating: in Vitro Evaluation of Blood Clot Lysis Using a 3D Microfluidic Model

Macromolecular Bioscience, EarlyView.
The functionalization of antifouling polymer brushes with tissue plasminogen activator resulted in a coating system that can direct blood components to digest blood clots in medical devices. This study further demonstrates the ability of this coating system to enhance clot‐lysis in fluid dynamic conditions that are close to the ones in extracorporeal ...
Lena Witzdam, Samarth Sandhu, Suji Shin, Yeahwa Hong, Shanzeh Kamal, Oliver Grottke, Keith E. Cook, Cesar Rodriguez‐Emmenegger   +7 more
wiley   +1 more source

Concomitant usage of thrombolytic therapy and therapeutic hypothermia in a case of sudden cardiac arrest due to massive pulmonary embolism

Türk Kardiyoloji Derneği Arşivi, 2019
Massive pulmonary embolism is a well-known cause of sudden cardiac arrest in the adult population. Systemic fibrinolysis can be a life-saving option. Therapeutic hypothermia is highly recommended for nontraumatic sudden cardiac arrest victims to minimize
Ali Çoner, Tayfun Birtay
doaj   +1 more source

Endogenous fibrinolysis facilitates clot retraction in vivo.

Blood, 2017
Clot retraction refers to the process whereby activated platelets transduce contractile forces onto the fibrin network of a thrombus, which over time increases clot density and decreases clot size.
A. Samson, I. Alwis, Jessica A A Maclean, Pramith Priyananda, Brian S. Hawkett, S. Schoenwaelder, S. Jackson   +6 more
semanticscholar   +1 more source

Development and Validation of a Capillary Electrophoresis Coupled to Mass Spectrometry Pipeline for Comparable Assessment of the Plasma Peptidome

PROTEOMICS, EarlyView.
ABSTRACT Although capillary electrophoresis coupled to mass spectrometry (CE‐MS) holds promise for urinary peptide profiling, only a limited number of studies have used CE‐MS to study plasma peptides. Here we describe the establishment of a workflow, including sample preparation, CE‐MS analysis, data processing and normalization optimized for the ...
Lucie Fernandez, Benjamin Breuil, Carine Froment, Mouhamed Seye, Babacar Sylla, Marina Estanco, Adeline Chaubet, Eléonore Delecroix, Karima Chaoui, Jeanne Pierrette Vu, Serban Ardeleanu, Stanislas Faguer, Odile Burlet‐Schiltz, Bénédicte Buffin‐Meyer, Joost P. Schanstra, Julie Klein   +15 more
wiley   +1 more source

Heart failure guideline implementation in developing countries: A testimony from Syria

European Journal of Heart Failure, EarlyView.
Amr Abdin, Mohammad Bashar Izzat, Ahmad Rasheed Alsaadi, Asim Katbeh, Yassin Bani Marjeh, Suleman Aktaa   +5 more
wiley   +1 more source