Results 81 to 90 of about 99,108 (283)

Establishment and Validation of a C57BL/6J Mouse Model for Melasma

Cell Proliferation, EarlyView.
A melasma‐like mouse model was established in C57BL/6J mice using a combination of UVB irradiation, progesterone administration, and chronic psychological stress. This model replicates key clinical features and biomarker alterations observed in human melasma. Importantly, it is fundamentally distinct from UV‐induced post‐inflammatory hyperpigmentation (
Wenzhu Wang, Xiaojie Sun, Yunyao Liu, Yin Yang, Hedan Yang, Xiaoli Zhang, Xiuzhen Li, Haoxiang Xu, Xu Chen, Tong Lin   +9 more
wiley   +1 more source

Expression of plasma prekallikrein mRNA in human nonhepatic tissues and cell lineages suggests special local functions of the enzyme [PDF]

, 1999
At present it is generally accepted that plasma prekallikrein (PPK) is synthesized in the liver and secreted into the bloodstream. Surprisingly, it has recently been shown that PPK mRNA is present also in RNA from the kidney, adrenal gland and placenta ...
Arnhold, Marianne, Fink, Edwin, Hermann, Andrea, Kresse, Hans, Neth, Peter   +4 more
core   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur, Christopher Dowson, Susan M. Bissett, Rachel van de Merwe, John J. Taylor, Philip M. Preshaw, Katrin M. Jaedicke   +6 more
wiley   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Systemic effects of tissue plasminogen activator-associated fibrinolysis and its relation to thrombin generation in orthotopic liver transplantation [PDF]

, 1989
Orthotopic liver transplantation is frequently associated with hyperfibrinolysis, the origin and clinical relevance of which is largely unknown. In 20 orthotopic liver transplantations, we studied the occurrence and systemic effects of hyperfibrinolysis.
Bontempo, FA, Kang, YG, Knot, EAR, Lewis, JH, Porte, RJ, Starzl, TE   +5 more
core   +1 more source

Intrathecal Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage: Evidence From Randomized Controlled Trials and Cohort Studies

Frontiers in Neurology, 2019
Background: The role of intrathecal fibrinolysis for the treatment of patients with aneurysmal subarachnoid hemorrhage (aSAH) has been widely investigated; however, the results have been contradictory.
Xiaocheng Lu, Chengyuan Ji, Jiang Wu, Wanchun You, Wei Wang, Zhong Wang, Gang Chen   +6 more
doaj   +1 more source

Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures

Journal of Periodontal Research, EarlyView.
Gingival recessions treated with a collagen matrix loaded with rhPDGF showed significantly greater early tissue perfusion compared to sites treated without the growth factor. Early tissue perfusion outcomes were correlated to the amount of root coverage and gingival thickness gain at 6 months.
Lorenzo Tavelli, Tu Nguyen, Maria Vera Rodriguez, Leonardo Mancini, William V. Giannobile, Shayan Barootchi   +5 more
wiley   +1 more source

Fibrinolysis [PDF]

Proceedings of the Royal Society of Medicine, 1971
  +12 more sources

Comparison of results obtained using clot-fibrinolysis waveform analysis and global fibrinolysis capacity assay with rotational thromboelastography

Scientific Reports
Global fibrinolysis assays detect the fibrinolysis time of clot dissolution using tissue-type plasminogen activator (tPA). Two such assays, clot-fibrinolysis waveform analysis (CFWA) and global fibrinolysis capacity (GFC) assay, were recently developed ...
Takumi Tsuchida, Mineji Hayakawa, Osamu Kumano   +2 more
doaj   +1 more source

Massive Bleeding as the First Clinical Manifestation of Metastatic Prostate Cancer due to Disseminated Intravascular Coagulation with Enhanced Fibrinolysis

Case Reports in Hematology, 2016
Disseminated intravascular coagulation (DIC) is the most frequent coagulation disorder associated with metastatic prostate adenocarcinoma. However, DIC with enhanced fibrinolysis as an initial presentation of prostate cancer is extremely rare.
Mónica Palma Anselmo, Gustavo Nobre de Jesus, João Madeira Lopes, Rui M. M. Victorino, João Meneses Santos   +4 more
doaj   +1 more source