Results 171 to 180 of about 1,529,288 (217)

Fibrinolytic agents

Fibrinolysis, 1995
exaly   +2 more sources

The effect of fibrinolytic agents on myocardial infarction

Progress in Cardiovascular Diseases, 1960
John S Ladue, Eugene E Cliffton, E E Cliffton   +2 more
exaly   +3 more sources

The clinical use of fibrinolytic agents

The American Journal of Surgery, 1977
Two fibrinolytic drugs, streptokinase and urokinase, have undergone extensive clinical evaluation in the past fifteen years. Current evidence suggests that these agents may become the drugs of choice in the treatment of certain patients with venous thrombosis and pulmonary embolism.
J M, Porter, S H, Goodnight
openaire   +2 more sources

Development of New Fibrinolytic Agents

Current Pharmaceutical Design, 2006
Since the activation of coagulation system and platelets triggers the thrombosis, the agents possessing anticoagulation or anti-platelet function have been used for the antithrombotic procession actions. However, in the physiological condition, the fibrinolytic system serves as antithrombotic, which removes the thrombus from the circulation.
Shigeru, Ueshima, Osamu, Matsuo
openaire   +2 more sources

[Enzymatic fibrinolytic agents].

Annales de l'anesthesiologie francaise, 1979
Urokinase (UK) and streptokinase (SK) transform plasminogen into plasmin by rupture of a ARG-VAL bond and the liberation of a peptide with a molecular weight of 6000 to 8000. Urokinase is a physiological activator with a direct action. By contrast, streptokinase is an enzyme of bacterial origin and two hypotheses may be advanced to explain its ...
M, Jamet, C, Granthil, G, Levy
openaire   +2 more sources

Comparison of Caseinolytic and Fibrinolytic Assays for Plasmin (Fibrinolysin) in “Fibrinolytic Agents”

Thrombosis and Haemostasis, 1966
Summary1. Caseinolytic and fibrinolytic systems for assay of plasmin in fibrinolytic agents are described which are based upon the determinations of AE/min during the linear portion of the casein-plasmin and fibrin-plasmin reaction curves respectively. A " caseinolytic-rate " unit and “fibrinolytic-rate " unit of ÄE/min × 103 during the linear portion ...
K M, Moser, M B, Frey
openaire   +2 more sources

Tenecteplase: A promising new fibrinolytic agent

Dimensions of Critical Care Nursing, 2001
Acute coronary syndrome can mean anything from unstable angina to acute myocardial infarction (MI) with ST-segment elevation. Tenecteplase, a new fibrinolytic agent used to treat ST-segment elevation acute MI, has some advantages over other fibrinolytic agents. This article describes tenecteplase's actions, indications, contraindications, and use.
M J, De Jong, W, Sabadie-Garretson
openaire   +2 more sources

Tenecteplase: A fibrinolytic agent

British Journal of Cardiac Nursing, 2006
Thrombolysis is an established therapy for acute myocardial infarction in the UK. ST-elevation myocardial infarction almost always occurs owing to coronary atherosclerosis and coronary thrombosis which develops because of plaque disruption. Fibrinolytic agents act to dissolve the clot.
openaire   +1 more source

Fibrinolytic Agents: Mechanisms of Activity and Pharmacology

Thrombosis and Haemostasis, 1995
Fibrinolytic (thrombolytic) agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the active enzyme plasmin, that degrades fibrin. Agents available for clinical use are: the physiologic tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA)--either in a single chain (scu-PA ...
H R, Lijnen, D, Collen
openaire   +2 more sources

ROLE OF FIBRINOLYTIC AGENTS IN THROMBOTIC DISEASES

Journal of the American Medical Association, 1960
Critical analysis of existing data demonstrates that fibrinolysin in conjunction with anticoagulant therapy decreases the morbidity in patients with thrombophlebitis. This conclusion was the result of comparison of data from hospital charts of 20 patients in a fibrinolysin-treated series and a control group of 22 patients. The comparison was made after
R V, CHAPPLE, H O, SINGHER
openaire   +2 more sources