Fermentation, 2023 Fibrinolytic enzymes are a kind of proteolytic enzymes that can hydrolyze fibrin and dissolve blood clots. They could be used as a therapeutic agent for treating thrombosis.
Zixuan He +8 more
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Journal of Pure and Applied Microbiology, 2017 Marine ecosystems house a plethora of microorganisms capable of producing therapeutically important metabolites, but remains largely unexplored. The aim of this work was to find a new marine bacterium capable of producing a fibrinolytic enzyme, which is ...
Anusha Krishnamurthy +3 more
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Breeding of high-yield Douchi fibrinolytic enzyme strain by ultraviolet mutagenesis and optimization of enzyme-producing conditions [PDF]
Zhongguo niangzaoUsing Douchi fibrinolytic enzyme-producing strain Bacillus subtilis DC-1 isolated from Douchi samples as the original strain, the high- yield Douchi fibrinolytic enzyme strain with stable inheritance was bred by ultraviolet mutagenesis, and the ...
ZHANG Wenyong, ZHANG Henghui, WANG Xiaoli
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Journal of Pharmacopuncture, 2011 Objectives: Fibrinolytic enzyme preparations were isolated from the snake venom of Macrovipera lebetica turanica in this study. Methods: The purity of the preparations was determined using SDS-PAGE and the enzymic characteristics of the purified ...
Kwon Ki-Rok +3 more
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Food Origin Fibrinolytic Enzyme With Multiple Actions [PDF]
Hayati Journal of Biosciences, 2017 Many health related problems such as cardiovascular diseases are associated with the formation of excessive clot in the blood (thrombus). Approaches in cardiovascular disease treatment are preventing the formation or removing the thrombus.
Laurentia Stephani +5 more
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Bioconversion of agro-industrial wastes for the production of fibrinolytic enzyme from Bacillus halodurans IND18: Purification and biochemical characterization [PDF]
Electronic Journal of Biotechnology, 2016 Background: Agro-wastes were used for the production of fibrinolytic enzyme in solid-state fermentation. The process parameters were optimized to enhance the production of fibrinolytic enzyme from Bacillus halodurans IND18 by statistical approach.
Ponnuswamy Vijayaraghavan +3 more
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Purification and Characterization of a Novel Fibrinolytic Enzyme from Marine Bacterium Bacillus sp. S-3685 Isolated from the South China Sea [PDF]
Marine DrugsA novel fibrinolytic enzyme, BSFE1, was isolated from the marine bacterium Bacillus sp. S-3685 (GenBank No.: KJ023685) found in the South China Sea.
Zibin Ma +3 more
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Fibrinolytic Enzyme from Green Microalgae: A New Potential Drug for Thrombolytic Therapy?
Phycology, 2023 Thrombosis is characterized by the pathological formation of fibrin clots within a blood vessel, leading to the obstruction of blood flow. Fibrinolytic enzymes from microorganisms have been shown to be more efficient and safer in dissolving clots.
Yanara Alessandra Santana Moura +5 more
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Purification and Characterisation of a Fibrinolytic Enzyme from Rhizopus micro sporus var. tuberosus [PDF]
Food Technology and Biotechnology, 2015 Extracellular fibrinolytic enzyme from Rhizopus microsporus var. tuberosus was purified and characterised. The microorganism was isolated in a distillery from daqu, a fermentative agent used in the production of Chinese liquor and vinegar at diff erent ...
Shuli Zhang +6 more
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Velefibrinase: A Marine-Derived Fibrinolytic Enzyme with Multi-Target Antithrombotic Effects Across Diverse In Vivo Models [PDF]
BiomedicinesBackground/Objectives: Thrombotic diseases (TDs), currently the number one killer worldwide, account for the highest mortality rate globally. In this study, we evaluated the antithrombotic efficacy of Velefibrinase, a marine bacteria-derived fibrinolytic
Yuting Zhou +5 more
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