Results 21 to 30 of about 4,822,589 (177)

Fibroblast-like synoviocytes dependent terminal differentiation of naïve B cells is inhibited compared to IgD+ memory B cells

, 2023
Data used for the manuiscript "Fibroblast-like synoviocytes dependent terminal differentiation of naïve B cells is inhibited compared to IgD+ memory B cells". Tables are formated as CSV files.
Dennis Bleck (6705434)
core   +1 more source

Expression of interleukin-18 receptor in fibroblast-like synoviocytes [PDF]

, 2001
An excess of the proinflammatory substance IL-18 is present in joints of patients with rheumatoid arthritis (RA), and expression of IL-18 receptor (IL-18R) regulates IL-18 bioactivity in various cell types.
Hoelzer, Dieter (Prof. Dr.), Rehart, Stefan, Kalina, Uwe, Kessler, Uta, Kukoc-Zivojnov, Natasa, Kaltwasser, Joachim Peter (Prof. Dr.), Ottmann, Oliver G., Möller, Burkhard, Uta Kessler, Oliver G Ottmann, Burkhard Möller, Natasa Kukoc-Zivojnov, Stefan Rehart, Joachim Peter Kaltwasser, Uwe Kalina, Dieter Hoelzer   +15 more
core   +1 more source

Angiotensin II protects fibroblast-like synoviocytes from apoptosis via the AT1-NF-kappaB pathway [PDF]

, 2007
To evaluate the effects of angiotensin II (Ang II) treatment on apoptosis of fibroblast-like synoviocytes (FLS) from patients with osteoarthritis (OA) and rheumatoid arthritis (RA)
Albertazzi, L, L. Pattacini, C. Salvarani, N. Pipitone, Casali, B, L. Albertazzi, Pipitone, N, SALVARANI, CARLO, Boiardi, L, Pattacini, L, L. Boiardi, B. Casali   +11 more
core   +1 more source

Synoviocyte cultures from synovial fluid

Reumatismo, 2011
The study of the pathogenetic mechanisms of rheumatic diseases is in general carried out through “in vitro” systems based on cellular cultures models.
L. Punzi, A. Pozzuoli, F. Calabrese, R. Luisetto, R. Ramonda, L. Braghetto, F. Oliviero, A. Scanu   +7 more
doaj   +1 more source

Role of Fibroblast Activation Protein Alpha in Fibroblast-like Synoviocytes of Rheumatoid Arthritis

Iranian Journal of Allergy, Asthma and Immunology, 2021
Fibroblast-like synoviocytes (FLSs) have been introduced in recent years as a key player in the pathogenesis of rheumatoid arthritis (RA), but the exact mechanisms of their transformation and intracellular pathways have not yet been determined.
Mohammad Javad Mousavi, Elham Farhadi, Mohammad Vodjgani, Jafar Karami, Mohammad Naghi Tahmasebi, Arash Sharafat Vaziri, Marzieh Asgari, Nima Rezaei, Shayan Mostafaei, Ahmadreza Jamshidi, Mahdi Mahmoudi   +10 more
doaj   +1 more source

Inhibition of lncRNA NEAT1 induces dysfunction of fibroblast-like synoviocytes in rheumatoid arthritis via miRNA-338-3p-mediated regulation of glutamine metabolism

Journal of Orthopaedic Surgery and Research, 2022
Background Rheumatoid arthritis (RA) is a systemic chronic autoimmune disease; cellular glutamine metabolism in fibroblast-like synoviocytes (FLSs) of RA was known to be essential for RA pathogenesis and progression.
Mei Zhang, Ning Lu, Hong-Jun Li, Xiao-Yun Guo, Lu Lu, Ying Guo   +5 more
doaj   +1 more source

Circ_0088194 Promotes the Invasion and Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the miR-766-3p/MMP2 Axis

Frontiers in Immunology, 2021
Dysregulation of circular RNAs (circRNAs) is involved in various human diseases. Fibroblast-like synoviocytes (FLSs), which form the lining of the joint, are epigenetically imprinted with an aggressive phenotype and contribute to joint destruction in ...
Yujie Cai, Renge Liang, Shibai Xiao, Qin Huang, Dingji Zhu, Guo-Ping Shi, Qingqing Ouyang, Min Yang   +7 more
doaj   +1 more source

Where to Stand with Stromal Cells and Chronic Synovitis in Rheumatoid Arthritis?

Cells, 2019
The synovium exercises its main function in joint homeostasis through the secretion of factors (such as lubricin and hyaluronic acid) that are critical for the joint lubrication and function.
Jean-Marc Brondello, Farida Djouad, Christian Jorgensen   +2 more
doaj   +1 more source

IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. [PDF]

PLoS Biology, 2012
Interleukin-26 (IL-26), a member of the IL-10 cytokine family, induces the production of proinflammatory cytokines by epithelial cells. IL-26 has been also reported overexpressed in Crohn's disease, suggesting that it may be involved in the ...
Murielle Corvaisier, Yves Delneste, Henry Jeanvoine, Laurence Preisser, Simon Blanchard, Erwan Garo, Emmanuel Hoppe, Benjamin Barré, Maurice Audran, Béatrice Bouvard, Jean-Paul Saint-André, Pascale Jeannin   +11 more
doaj   +1 more source

Dimethyl Sulfoxide: A Bio-Friendly or Bio-Hazard Chemical? The Effect of DMSO in Human Fibroblast-like Synoviocytes

Molecules, 2022
The effect of dimethyl sulfoxide (DMSO) in rheumatoid arthritis (RA) human fibroblast-like synoviocytes (FLSs) has been studied on five different samples harvested from the joints (fingers, hands and pelvis) of five women with RA. At high concentrations (
Manuel Gallardo-Villagrán, Lucie Paulus, David Yannick Leger, Bruno Therrien, Bertrand Liagre   +4 more
doaj   +1 more source