Results 51 to 60 of about 18,476 (229)

Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid-lysophosphatidic acid receptor 1 cascade [PDF]

, 2014
INTRODUCTION: Lysophosphatidic acid (LPA) is a bioactive lipid that binds to G protein–coupled receptors (LPA(1–6)). Recently, we reported that abrogation of LPA receptor 1 (LPA(1)) ameliorated murine collagen-induced arthritis, probably via inhibition ...
Chie Miyabe, Chiyoko Sekine, Kazutaka Sugimoto, Masayoshi Harigai, Masayuki Miyasaka, Nobuyuki Miyasaka, Toshihiro Nanki, Waka Yokoyama, Yoshiko Iwai, Yoshishige Miyabe   +9 more
core   +1 more source

Cadherin 11 promotes invasive behavior of fibroblast‐like synoviocytes [PDF]

Arthritis & Rheumatism, 2009
AbstractObjectiveTo define the expression pattern of cadherin 11 in the destructive pannus tissue of patients with rheumatoid arthritis, and to determine whether cadherin 11 expression in fibroblast‐like synoviocytes controls their invasive capacity.MethodsCadherin 11 expression in rheumatoid synovial tissue was evaluated using immunohistochemistry. To
Hans P, Kiener, Birgit, Niederreiter, David M, Lee, Esther, Jimenez-Boj, Josef S, Smolen, Michael B, Brenner   +5 more
openaire   +2 more sources

TNF induces glycolytic shift in fibroblast like synoviocytes via GLUT1 and HIF1A

Scientific Reports, 2021
TNF is a central cytokine in the pathogenesis of rheumatoid arthritis (RA). Elevated level of TNF causes local inflammation that affects immune cells and fibroblast-like synoviocytes (FLS). Nowadays, only 20–30% of patients experience remission after the
Kathrin Koedderitzsch, Ekaterina Zezina, Lingzi Li, Matthias Herrmann, Nadine Biesemann   +4 more
doaj   +1 more source

Synovial cysts of the temporomandibular joint: an immunohistochemical characterization and literature review. [PDF]

, 2013
Synovial cysts of the temporomandibular joint (TMJ) are very rare, and to date, only 12 cases of a synovial cyst in the TMJ region have been reported in the literature.
Baquero, C., Tomás-Amerigo, J.A., Vera Sempere, Francisco José, Vera-Sirera, Beatriz   +3 more
core   +2 more sources

Identification and validation of hub gene TNFAIP6 of fibroblast-like synoviocytes in rheumatoid arthritis

陆军军医大学学报
Objective‍　‍To identify the hub gene of fibroblast-like synoviocytes in rheumatoid arthritis (RA) and verify its impact on proliferation, migration and invasion of the cells.
LEI Lei, LYU Yuxin, ZHANG Jing
doaj   +1 more source

An overview of carbonic anhydrases and membrane channels of synoviocytes in inflamed joints

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
The highly aggressive fibroblast-like synoviocytes (FLSs) are inflammatory mediators involved in synovial joint destruction. Membrane channels and transporters are essential components of the cell migration apparatus and are involved in various cellular ...
Min Jeong Ji, Jeong Hee Hong
doaj   +1 more source

Brucella and Osteoarticular Cell Activation: Partners in Crime [PDF]

, 2017
Osteoarticular brucellosis is the most common presentation of human active disease although its prevalence varies widely. The three most common forms of osteoarticular involvement are sacroiliitis, spondylitis, and peripheral arthritis.
Adamopoulos, Adarichev, Al-Eissa, Aydin, Azuma, Bartok, Behera, Bivi, Bonewald, Burrage, Buzgan, Cenci, Chen, Civitelli, Colmenero, Delpino, Delpino, Delpino, D’Amelio, D’Amelio, El-Jawhari, Farkas, Fuller, Garcia Samartino, Geiger, Giambartolomei, Giambartolomei, Gilmore, Goenka, Goenka, Golding, Gotuzzo, Grundt, Haynes, Horowitz, Ibero, Ikeda, Inman, Karner, Kasim, Kawai, Kitazawa, Kobayashi, Kollet, Kong, Kotake, Lacey, Lampiasi, Lerner, Madkour, Madkour, Magnani, Merkel, Milner, Mori, Nair, Nakayamada, Pappas, Pappas, Pesce Viglietti, Press, Prideaux, Rajapakse, Rajashekara, Rodan, Roggia, Sato, Scian, Scian, Scian, Scian, Shaalan, Skyberg, Soder, Song, Streuli, Takayanagi, Takayanagi, Takayanagi, Tanaka, Teitelbaum, Thomson, Tokoyoda, Turan, Viau, Visnjic, Wallach, Wei, Yasuda, Young, Young, Zhan, Zhan, Zhan, Zhao, Zwerdling   +95 more
core   +1 more source

FRI0033 Erythropoietin-receptor-expression in fibroblast-like synoviocytes [PDF]

Annals of the Rheumatic Diseases, 2001
Background The anaemia of chronic disease in patients with rheumatoid arthritis (RA) can be corrected by treatment with recombinant human erythropoietin (rHu-Epo). In addition to an increase of haemoglobin concentration during therapy with rHu-Epo, a significant reduction of disease activity was observed in different RA-studies.
U Kessler, S Woelfer, N Kukoc-Zivojnov, JP Kaltwasser, B Moeller   +4 more
openaire   +1 more source

Expression and Localization of aquaporin‐1 in Temporomandibular Joint Disc with Internal Derangement [PDF]

, 2012
Background: Internal derangement is the most frequent arthropathy affecting the temporomandibular joint, where its commonest form is anterior disc displacement with or without reduction.
Almeida, Luis Eduardo, Caltabiano, Rosario, Carnazza, Maria Luisa, Galanti, Concetta, Leonardi, Rosalia, Loreto, Carla, Musumeci, Giuseppe, Pannone, Giuseppe   +7 more
core   +2 more sources

CCL18 Activates Fibroblast-like Synoviocytes in Patients with Rheumatoid Arthritis [PDF]

The Journal of Rheumatology, 2013
To the Editor: Fibroblast-like synoviocytes (FLS) proliferate in the synovial tissue of patients with rheumatoid arthritis (RA), and contribute to chronic inflammation and the destruction of articular cartilage due to the production of a variety of cytokines, chemokines, and matrix metalloproteinases (MMP)1.
Aiko, Takayasu, Yoshishige, Miyabe, Waka, Yokoyama, Kayoko, Kaneko, Shin, Fukuda, Nobuyuki, Miyasaka, Chie, Miyabe, Tetsuo, Kubota, Toshihiro, Nanki   +8 more
openaire   +2 more sources