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Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis [PDF]
Cytokine & Growth Factor Reviews, 2005 Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans, and integrins.
PRESTA, Marco +5 more
openaire +4 more sources
Neural Regeneration Research, 2023 Interfering with the ferroptosis pathway is a new strategy for the treatment of spinal cord injury. Fibroblast growth factor 21 can inhibit ferroptosis and promote neurofunctional recovery, while heme oxygenase-1 is a regulator of iron and reactive ...
Qi Gu +10 more
doaj +2 more sources
Fibroblast Growth Factors in Depression [PDF]
Frontiers in Pharmacology, 2019 Major depressive disorder (MDD) is one of the most serious diseases and now becomes a major public health problem in the world. The pathogenesis of depression remains poorly understood.
Zheng Deng +7 more
doaj +3 more sources
Overexpression of fibroblast growth factor 13 ameliorates amyloid-β-induced neuronal damage
Neural Regeneration Research, 2023 Previous studies have shown that fibroblast growth factor 13 is downregulated in the brain of both Alzheimer’s disease mouse models and patients, and that it plays a vital role in the learning and memory.
Ruo-Meng Li +4 more
doaj +1 more source
Indian Journal of Health Sciences and Biomedical Research KLEU, 2020 Fibroblast growth factor (FGF) family members are mostly secreted as signaling proteins with diverse functions in development and metabolism. FGFs can be classified as intracellular, paracrine, and endocrine FGFs by their action mechanisms.
Leta Shiferaw Melaku, Negeri Debela
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Animals, 2021 The oviduct presents the ideal conditions for fertilization and early embryonic development. In this study, (i) vascularization pattern; (ii) microvascular density; (iii) transcripts of angiogenic factors (FGF1, FGF2, VEGF) and their receptors—FGFR1 ...
Pedro Pinto-Bravo +10 more
doaj +1 more source
Fibroblast Growth Factor 2—A Review of Stabilisation Approaches for Clinical Applications
Pharmaceutics, 2020 Basic fibroblast growth factor (FGF)-2 has been shown to regulate many cellular functions including cell proliferation, migration, and differentiation, as well as angiogenesis in a variety of tissues, including skin, blood vessel, muscle, adipose, tendon/
Leah Benington +3 more
doaj +1 more source
Role of Rhodomyrtus tomentosa (Aiton) Hassk. in regulating the expression of fibroblast growth factor family in the liver of rat in a breast cancer model [PDF]
Journal of Pharmacy & Pharmacognosy ResearchContext: Cellular abnormalities in the ducts and breast tissue cause breast cancer to invade nearby tissues like the liver. The fibroblast growth factor (FGF) signals are sent to its receptor and regulate various cellular processes to maintain liver ...
Putri Cahaya Situmorang +6 more
doaj +1 more source
Analysis of the Effects of Five Factors Relevant to In Vitro Chondrogenesis of Human Mesenchymal Stem Cells Using Factorial Design and High Throughput mRNA-Profiling [PDF]
, 2014 The in vitro process of chondrogenic differentiation of mesenchymal stem cells for tissue engineering has been shown to require three-dimensional culture along with the addition of differentiation factors to the culture medium.
Brinchmann, Jan E. +4 more
core +11 more sources
Fibroblast growth factor 21 and bone homeostasis
Biomedical Journal, 2023 Fibroblast growth factor 21 (FGF21), a member of the FGF subfamily, is produced primarily in the liver and adipose tissue. The main function of FGF21 is to regulate energy metabolism of carbohydrates and lipids in the body through endocrine and other ...
Yan Tang, Mei Zhang
doaj +1 more source