Results 11 to 20 of about 547,171 (369)
Regulation of Fibroblast Growth Factor-23 Signaling by Klotho* [PDF]
Journal of Biological Chemistry, 2006 The aging suppressor gene Klotho encodes a single-pass transmembrane protein. Klotho-deficient mice exhibit a variety of aging-like phenotypes, many of which are similar to those observed in fibroblast growth factor-23 (FGF23)-deficient mice. To test the
H. Kurosu +10 more
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Phosphate and fibroblast growth factor 23 in diabetes [PDF]
Clinical science, 2021 Diabetes is associated with a strongly elevated risk of cardiovascular disease, which is even more pronounced in patients with diabetic nephropathy. Currently available guideline-based efforts to correct traditional risk factors are only partly able to ...
A. van der Vaart +4 more
semanticscholar +3 more sources
Physiological Actions of Fibroblast Growth Factor-23
Frontiers in Endocrinology, 2018 Fibroblast growth factor-23 (FGF23) is a bone-derived hormone suppressing phosphate reabsorption and vitamin D hormone synthesis in the kidney. At physiological concentrations of the hormone, the endocrine actions of FGF23 in the kidney are αKlotho ...
Reinhold G. Erben
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Role of Fibroblast Growth Factor 23 (FGF23) and αKlotho in Cancer
Frontiers in Cell and Developmental Biology, 2021 Together with fibroblast growth factors (FGFs) 19 and 21, FGF23 is an endocrine member of the family of FGFs. Mainly secreted by bone cells, FGF23 acts as a hormone on the kidney, stimulating phosphate excretion and suppressing formation of 1,25(OH)2D3 ...
Franz Ewendt +2 more
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Bone mass does not correlate with the serum fibroblast growth factor 23 in hemodialysis patients [PDF]
, 2007 Circulating fibroblast growth factor 23 (FGF23) increases renal phosphate excretion, decreases bone mineralization and is markedly increased in hemodialysis patients. Bone cells express fibroblast growth receptor 1, suggesting that FGF23 could alter bone
Pablo Ureña-Torres +4 more
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Prognostic Importance of Fibroblast Growth Factor-23 in Dialysis Patients [PDF]
International Journal of Nephrology, 2014 Introduction. In this study, we aimed to demonstrate the correlation of FGF-23 levels with bone-mineral metabolism, anemia, and the treatment in dialysis patients. Methods.
Nilgül Akalin +5 more
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Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men [PDF]
Pflügers Archiv: European Journal of Physiology, 2018 Fibroblast growth factor 23 (FGF23) is a major endocrine regulator of phosphate and 1,25 (OH)2 vitamin D3 metabolism and is mainly produced by osteocytes. Its production is upregulated by a variety of factors including 1,25 (OH)2 vitamin D3, high dietary
A. Daryadel +8 more
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Indian Journal of Endocrinology and Metabolism, 2011 Introduction: Secondary hyperparathyroidism (SHPT) is an insidious disease that develops early in the course of chronic kidney disease (CKD) and increases in severity as the glomerular filtration rate deteriorates.
Hamdy Sliem +3 more
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Fibroblast growth factor 23 and symmetric dimethylarginine concentrations in geriatric cats [PDF]
Journal of Veterinary Internal Medicine, 2019 Background Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that is increased in azotemic cats with chronic kidney disease (CKD) and predictive of the onset of azotemia in older cats.
Hannah J. Sargent +5 more
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Direct and indirect effects of fibroblast growth factor 23 on the heart
Frontiers in Endocrinology, 2023 Fibroblast growth factor (FGF)23 is a bone-derived phosphotropic hormone that regulates phosphate and mineral homeostasis. Recent studies have provided evidence that a high plasma concentration of FGF23 is associated with cardiac disease, including left ...
T. Nakano, H. Kishimoto, M. Tokumoto
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