Fibroblast growth factors [PDF]
Current Biology, 2003 What are they? Fibroblast growth factors (FGFs) are a family of small (20–30kDa) intercellular signalling proteins which are frequently found to be glycosylated. The first draft of the human genome identified 29 potential FGF genes, and so far transcripts have been identified for 23 of them.
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Vascular Regeneration by Local Growth Factor Release Is Self-Limited by Microvascular Clearance [PDF]
, 2008 Background— The challenge of angiogenesis science is that stable sustained vascular regeneration in humans has not been realized despite promising preclinical findings.
Edelman, Elazer R. +5 more
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A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor. [PDF]
, 2013 Basic fibroblast growth factor (bFGF) is a protein that plays a crucial role in diverse cellular functions, from wound healing to bone regeneration.
Decker, Caitlin G +5 more
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Upstream Regulators of Fibroblast Growth Factor 23
Frontiers in Endocrinology, 2021 Fibroblast growth factor 23 (FGF23) has been described as an important regulator of mineral homeostasis, but has lately also been linked to iron deficiency, inflammation, and erythropoiesis. FGF23 is essential for the maintenance of phosphate homeostasis
Danielle M. A. Ratsma +2 more
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Alveolar fluid in acute respiratory distress syndrome promotes fibroblast migration: role of platelet-derived growth factor pathway [PDF]
, 2012 OBJECTIVES: Fibroblast migration is an initiating step in fibroproliferation; its involvement during acute lung injury and acute respiratory distress syndrome remains poorly understood. The aims of this study were: 1) to determine whether bronchoalveolar
A. Mailleux +10 more
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Comparative genomic analysis of eutherian fibroblast growth factor genes
BMC Genomics, 2020 Background The eutherian fibroblast growth factors were implicated as key regulators in developmental processes. However, there were major disagreements in descriptions of comprehensive eutherian fibroblast growth factors gene data sets including either ...
Marko Premzl
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Computer-assisted stabilization of fibroblast growth factor FGF-18
Computational and Structural Biotechnology Journal, 2023 The fibroblast growth factors (FGF) family holds significant potential for addressing chronic diseases. Specifically, recombinant FGF18 shows promise in treating osteoarthritis by stimulating cartilage formation.
Jan Vilim +8 more
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Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]
, 2017 An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto +6 more
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Fibroblast Growth Factor Inhibitors [PDF]
Journal of Thoracic Oncology, 2010 Dr. Ignatio Witsuba (MD Anderson) started this session by giving an overview of the fibroblast growth factor (FGF) pathway and expression of FGFs (22 members), FGF receptors (FGFRs, four members), and their gene family members in non-small cell lung cancer (NSCLC).
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Master regulators of FGFR2 signalling and breast cancer risk. [PDF]
, 2013 The fibroblast growth factor receptor 2 (FGFR2) locus has been consistently identified as a breast cancer risk locus in independent genome-wide association studies. However, the molecular mechanisms underlying FGFR2-mediated risk are still unknown. Using
Caldas, Carlos +10 more
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