Results 21 to 30 of about 514,253 (261)

Fibroblast Growth Factor Inhibitors [PDF]

Journal of Thoracic Oncology, 2010
Dr. Ignatio Witsuba (MD Anderson) started this session by giving an overview of the fibroblast growth factor (FGF) pathway and expression of FGFs (22 members), FGF receptors (FGFRs, four members), and their gene family members in non-small cell lung cancer (NSCLC).
openaire   +3 more sources

Fibroblast Growth Factors in Schizophrenia [PDF]

Schizophrenia Bulletin, 2009
A large association study by O'Donovan et al recently suggested that genetic variation in fibroblast growth factor receptor (FGFR) 2 increases the risk for developing schizophrenia. Fibroblast growth factors (FGFs) are part of the family of glial growth factors; they control the growth and patterning of specific brain structures and regulate the ...
Steven C. Bakker, Afke F. Terwisscha van Scheltinga, René S. Kahn   +2 more
openaire   +3 more sources

Fibroblast growth factor 21 in metabolic syndrome

Frontiers in Endocrinology, 2023
Metabolic syndrome is a complex metabolic disorder that often clinically manifests as obesity, insulin resistance/diabetes, hyperlipidemia, and hypertension.
Ming Yang, Ming Yang, Chongbin Liu, Chongbin Liu, Na Jiang, Na Jiang, Yan Liu, Yan Liu, Shilu Luo, Shilu Luo, Chenrui Li, Chenrui Li, Hao Zhao, Hao Zhao, Yachun Han, Yachun Han, Wei Chen, Wei Chen, Li Li, Li Li, Li Xiao, Li Xiao, Lin Sun, Lin Sun   +23 more
doaj   +1 more source

Functional interaction of fibroblast growth factor 8b and androgen in prostate cancer cell proliferation

Tumor Biology, 2017
Fibroblast growth factor 8b and androgen play important roles in cell proliferation of prostate cancer. We investigated the effects of fibroblast growth factor 8b and androgen on the proliferation of prostate cell lines and the corresponding ...
Wen-jun Xiao, Gui-ming Zhang, Ding-wei Ye   +2 more
doaj   +1 more source

In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor

Journal of Tissue Engineering, 2016
Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors.
Justine J Roberts, Brooke L Farrugia, Rylie A Green, Jelena Rnjak-Kovacina, Penny J Martens   +4 more
doaj   +1 more source

Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]

, 2017
An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto, Ferroni, Letizia, Gardin, Chiara, Mijiritsky, Eitan, Piattelli, Adriano, Zanette, Gastone, Zavan, Barbara   +6 more
core   +2 more sources

Role of Fibroblast Growth Factor Receptor 2 in Pancreatic Cancer: Potential Target for New Therapeutic Approach? [PDF]

, 2015
Fibroblast growth factors and their receptors play a key role in cell proliferation, migration and differentiation. Fibroblast growth factor receptor 2 (FGFR2) is involved in carcinogenesis and its altered expression has been shown in several tumors ...
Angeloni, Antonio, Ceccarelli, Simona, Vescarelli, Enrica   +2 more
core   +1 more source

Hyperphosphatemic Tumoral Calcinosis With Pemigatinib Use

AACE Clinical Case Reports, 2022
Background/Objective: Pemigatinib, a fibroblast growth factor receptor (FGFR) 1-3 inhibitor, is a novel therapeutic approach for treating cholangiocarcinoma when an FGFR fusion or gene rearrangement is identified.
Akshan Puar, MBBS, Diane Donegan, MD, Paul Helft, MD, Matthew Kuhar, MD, Jonathan Webster, MD, Megana Rao, BS, Michael Econs, MD   +6 more
doaj  

The Role of Fibroblast Growth Factor Receptors Inhibitors in Bladder Cancer [PDF]

Journal of Urologic Oncology
Dysregulation of fibroblast growth factor (FGF)-receptor (FGFR) signaling, which is implicated in various oncogenic processes, including tumor proliferation, survival, migration, invasion, and angiogenesis, has been identified as a critical factor in ...
Ho Kyung Seo, Eui Hyun Jung, Sora Yang, Hye Won Lee   +3 more
doaj   +1 more source

The key components of Schwann cell-like differentiation medium and their effects on gene expression pattern of adipose-derived stem cells. [PDF]

, 2015
BackgroundSchwann cell-like cells differentiated from adipose-derived stem cells may have an important role in peripheral nerve regeneration. Herein, we document the individual effects of growth factors in Schwann cell-like differentiation medium ...
Lankford, Lee, Little, Christopher J, Olson, Christine A, Orbay, Hakan, Sahar, David E   +4 more
core   +1 more source