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Fibroblast growth factor 2. [PDF]
DifferentiationFibroblast Growth Factor 2 (FGF2), also known as basic fibroblast growth factor, is a potent stimulator of growth and differentiation in multiple tissues. Its discovery traces back over 50 years ago when it was first isolated from bovine pituitary extracts due to its ability to stimulate fibroblast proliferation.
Nickle A, Ko S, Merrill AE.
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Biological Roles of Fibroblast Growth Factor-2* [PDF]
Endocrine Reviews, 1997 I. Introduction II. Structure of FGF-2 III. Mechanisms of Action of FGF-2: Extra- and Intracellular Signaling A. Exogenous 18-kDa FGF-2 B. Endogenous 18-kDa FGF-2 and HMW FGF-2 IV. Release of FGF-2 V. Roles of FGF-2 in Development and Differentiation in Various Organ Systems A. Mesoderm induction B. Angiogenesis C. Vessel wall D. Lung E.
A, Bikfalvi +3 more
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Fibroblast Growth Factor-2 (FGF-2). [PDF]
Science-Business eXchange, 2009 Epileptogenesis and epilepsy progression are associated with rearrangements of neuronal circuits mediated by such processes as sprouting, neuronal cell death, and neurogenesis. These processes lead to hyperexcitability, spontaneous seizures, and/or worsening of seizure severity/frequency. Neurotrophic factors, and the Fibroblast Growth Factor-2 (FGF-2)
SIMONATO, Michele, ZUCCHINI, Silvia
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Circulating fibroblast growth factor-2 precipitates HIV nephropathy in mice
Disease Models & Mechanisms, 2021 People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with HIVAN frequently show high plasma fibroblast growth factor-2 (FGF-2) levels; however, the role ...
Jharna R. Das +5 more
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Incorporation of FGF-2 into Pharmaceutical Grade Fucoidan/Chitosan Polyelectrolyte Multilayers
Marine Drugs, 2020 Biopolymer polyelectrolyte multilayers are a commonly studied soft matter system for wound healing applications due to the biocompatibility and beneficial properties of naturally occurring polyelectrolytes.
Natalie L. Benbow +3 more
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Intracellular trafficking of endogenous fibroblast growth factor‐2 [PDF]
The FEBS Journal, 2008 We have previously reported how the release of fibroblast growth factor‐2 (FGF‐2) is mediated by shed vesicles. In the present study, we address the question of how newly synthesized FGF‐2 is targeted to the budding vesicles. Considering that in vitro cultured Sk‐Hep1 hepatocarcinoma cells release FGF‐2 and shed membrane vesicles only when cultured in ...
Taverna Simona +3 more
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Fibroblast Growth Factor-2-induced Signaling through Lipid Raft-associated Fibroblast Growth Factor Receptor Substrate 2 (FRS2) [PDF]
Journal of Biological Chemistry, 2003 The plasma membrane is not homogeneous but contains specific subcompartments characterized by their unique lipid and protein composition. Based on their enrichment in various signaling molecules, these membrane microdomains are recognized to be sites of localized signal transduction for a number of extracellular stimuli.
Marc S, Ridyard, Stephen M, Robbins
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FGF2 (fibroblast growth factor 2 (basic)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on FGF2 (fibroblast growth factor 2 (basic)), with data on DNA, on the protein encoded, and where the gene is implicated.
MacFarlane, LA, Murphy, P
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Case Reports in Oncology, 2020 Pulmonary tumor thrombotic microangiopathy (PTTM) is characterized by tumor cell microemboli with occlusive fibrointimal remodeling in small pulmonary vessels.
Yusuke Kawanaka +7 more
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Journal of Applied Oral Science, 2016 Objective Biocompatible materials such as interconnected porous hydroxyapatite ceramics (IP-CHA) loaded with osteogenic cells and bioactive agents are part of an evolving concept for overcoming craniofacial defects by use of artificial bone tissue ...
Mohammad Zeshaan RAHMAN +5 more
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