Results 21 to 30 of about 316,940 (259)

Fibroblast growth factor 2 (FGF2) [PDF]

open access: yesScience-Business eXchange, 2009
Epileptogenesis and epilepsy progression are associated with rearrangements of neuronal circuits mediated by such processes as sprouting, neuronal cell death, and neurogenesis. These processes lead to hyperexcitability, spontaneous seizures, and/or worsening of seizure severity/frequency. Neurotrophic factors, and the Fibroblast Growth Factor-2 (FGF-2)
SIMONATO, Michele, ZUCCHINI, Silvia
openaire   +3 more sources

Retraction Note: Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes [PDF]

open access: yesArthritis Research & Therapy
Dongyao Yan   +6 more
doaj   +2 more sources

Biological Roles of Fibroblast Growth Factor-2* [PDF]

open access: yesEndocrine Reviews, 1997
I. Introduction II. Structure of FGF-2 III. Mechanisms of Action of FGF-2: Extra- and Intracellular Signaling A. Exogenous 18-kDa FGF-2 B. Endogenous 18-kDa FGF-2 and HMW FGF-2 IV. Release of FGF-2 V. Roles of FGF-2 in Development and Differentiation in Various Organ Systems A. Mesoderm induction B. Angiogenesis C. Vessel wall D. Lung E.
A, Bikfalvi   +3 more
openaire   +2 more sources

Circulating fibroblast growth factor-2 precipitates HIV nephropathy in mice

open access: yesDisease Models & Mechanisms, 2021
People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with HIVAN frequently show high plasma fibroblast growth factor-2 (FGF-2) levels; however, the role ...
Jharna R. Das   +5 more
doaj   +1 more source

Intracellular trafficking of endogenous fibroblast growth factor‐2 [PDF]

open access: yesThe FEBS Journal, 2008
We have previously reported how the release of fibroblast growth factor‐2 (FGF‐2) is mediated by shed vesicles. In the present study, we address the question of how newly synthesized FGF‐2 is targeted to the budding vesicles. Considering that in vitro cultured Sk‐Hep1 hepatocarcinoma cells release FGF‐2 and shed membrane vesicles only when cultured in ...
Taverna Simona   +3 more
openaire   +4 more sources

Incorporation of FGF-2 into Pharmaceutical Grade Fucoidan/Chitosan Polyelectrolyte Multilayers

open access: yesMarine Drugs, 2020
Biopolymer polyelectrolyte multilayers are a commonly studied soft matter system for wound healing applications due to the biocompatibility and beneficial properties of naturally occurring polyelectrolytes.
Natalie L. Benbow   +3 more
doaj   +1 more source

A Case of Pulmonary Tumor Thrombotic Microangiopathy Suggested by the Presence of Tumor Cells in Peripheral Blood

open access: yesCase Reports in Oncology, 2020
Pulmonary tumor thrombotic microangiopathy (PTTM) is characterized by tumor cell microemboli with occlusive fibrointimal remodeling in small pulmonary vessels.
Yusuke Kawanaka   +7 more
doaj   +1 more source

Effects of Fibroblast Growth Factor-2 on Longitudinal Bone Growth* [PDF]

open access: yesEndocrinology, 1998
In vivo, fibroblast growth factor-2 (FGF-2) inhibits longitudinal bone growth. Similarly, activating FGF receptor 3 mutations impair growth in achondroplasia and thanatophoric dysplasia. To investigate the underlying mechanisms, we chose a fetal rat metatarsal organ culture system that would maintain growth plate histological architecture.
E E, Mancilla   +4 more
openaire   +2 more sources

Combined effects of melatonin and FGF-2 on mouse preosteoblast behavior within interconnected porous hydroxyapatite ceramics - in vitro analysis

open access: yesJournal of Applied Oral Science, 2016
Objective Biocompatible materials such as interconnected porous hydroxyapatite ceramics (IP-CHA) loaded with osteogenic cells and bioactive agents are part of an evolving concept for overcoming craniofacial defects by use of artificial bone tissue ...
Mohammad Zeshaan RAHMAN   +5 more
doaj   +1 more source

Prognostic role of fibroblast growth factor receptor 2 in human solid tumors: A systematic review and meta-analysis

open access: yesTumor Biology, 2017
In the past decades, the oncogenic role of fibroblast growth factor receptor 2 has been demonstrated in a number of cancer types. However, studies have reported contradictory findings concerning the correlation between fibroblast growth factor receptor 2
Gang Liu   +3 more
doaj   +1 more source

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