Results 31 to 40 of about 316,940 (259)

A case of Pfeiffer syndrome with c833_834GC>TG (Cys278Leu) mutation in the gene [PDF]

Korean Journal of Pediatrics, 2010
Pfeiffer syndrome is a rare autosomal dominant disorder characterized by coronal craniosynostosis, brachycephaly, mid-facial hypoplasia, and broad and deviated thumbs and great toes.
Min Young Lee, Ga Won Jeon, Ji Mi Jung, Jong Beom Sin   +3 more
doaj   +1 more source

Fibroblast Growth Factor-2 (FGF-2) Expression in Pterygia Using Cell Spot Arrays

Vision, 2022
Fibroblast growth factor (FGF) is a main regulator of cell differentiation, cell migration and angiogenesis in normal and abnormal conjunctiva epithelia, but specific mechanisms of its aberrant expression are yet to be investigated. In the present study,
Stylianos Mastronikolis, Evangelos Tsiambas, Konstantinos Kagkelaris, Marina Pagkalou, Panagiotis Plotas, Sofianiki Mastronikoli, Dimitrios Roukas, Constantinos D. Georgakopoulos   +7 more
doaj   +1 more source

Fibroblast Growth Factors 1 and 2 and Fibroblast Growth Factor Receptor 1 Are Elevated in Thyroid Hyperplasia [PDF]

The Journal of Clinical Endocrinology & Metabolism, 1998
We have previously reported increased expression of fibroblast growth factor (FGF-1 and FGF-2) in benign and malignant human thyroid neoplasia. To determine the role of these factors in thyroid hyperplasia we have examined their expression in multinodular goiter and compared findings with those in normal thyroid tissue. Because the effects of FGF-1 and
S D, Thompson, J A, Franklyn, J C, Watkinson, J M, Verhaeg, M C, Sheppard, M C, Eggo   +5 more
openaire   +2 more sources

Fibroblast growth factor 2 is necessary for the antidepressant effects of fluoxetine. [PDF]

PLoS ONE, 2018
Previous research has shown that fibroblast growth factor 2 protein (FGF2) can act as an anxiolytic and anti-depressive agent in rodents. Levels of hippocampal FGF2 and FGF2 receptors are decreased in post-mortem brains of individuals with mood disorders.
Stephanie Simard, Pragya Shail, Jessica MacGregor, Maha El Sayed, Ronald S Duman, Flora M Vaccarino, Natalina Salmaso   +6 more
doaj   +1 more source

Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury

Neural Regeneration Research, 2022
The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited, especially in case of severe injury. This often leads to poor motor function and permanent disability.
Kamilla Faritovna Idrisova, Alina Kazymovna Zeinalova, Galina Andreevna Masgutova, Alexey Andreevich Bogov, Cinzia Allegrucci, Valeriia Yurievna Syromiatnikova, Ilnur Ildusovich Salafutdinov, Ekaterna Evgenievna Garanina, Dina Ivanovna Andreeva, Adilet Abdullaatovich Kadyrov, Albert Anatolevich Rizvanov, Ruslan Faridovich Masgutov   +11 more
doaj   +1 more source

Role of Lactoferrinin Fibroblast Growth Factor 2 and Vascular Endothelial Growth Factor in Gingival Wounds [PDF]

Journal of Krishna Institute of Medical Sciences University, 2019
Background: Lactoferrin possesses the ability to promote migration and proliferation of fibroblasts which represents one potential reason for the use of lactoferrin to accelerate the healing process in gingival wounds.
Istiati, Intan Nirwana, Indra Surjono, Meircurius Dwi Condro Surboyo   +3 more
doaj  

Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients

Journal of Translational Medicine, 2011
Background Non-gastrointestinal stromal tumor soft-tissue sarcomas (non-GIST STSs) constitute a heterogeneous group of tumors with poor prognosis. Fibroblast growth factor 2 (FGF2) and fibroblast growth factor receptor-1 (FGFR-1), in close interplay with
Smeland Eivind, Sorbye Sveinung W, Valkov Andrej, Kilvaer Thomas K, Bremnes Roy M, Busund Lill-Tove, Donnem Tom   +6 more
doaj   +1 more source

Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout mice

Scientific Reports, 2021
Fibroblast growth factor 2 (FGF2) is important in musculoskeletal homeostasis, therefore the impact of reduction or Fgf2 knockout on skeletal muscle function and phenotype was determined.
C. Homer-Bouthiette, L. Xiao, Marja M. Hurley   +2 more
doaj   +1 more source

Fibroblast growth factor 2 isoforms and cardiac hypertrophy [PDF]

Cardiovascular Research, 2004
Fibroblast growth factor 2 (FGF-2), a multifunctional polypeptide that affects cell growth and differentiation and becomes upregulated by stress, is expressed as AUG-initiated 18 kDa FGF-2 or CUG-initiated 21-34 kDa (hi-FGF-2) isoforms. Animal models have provided strong evidence that FGF-2 is essential for the manifestation of overload- and ...
Elissavet, Kardami, Zhi-Sheng, Jiang, Sarah K, Jimenez, Cheryl J, Hirst, Farah, Sheikh, Peter, Zahradka, Peter A, Cattini   +6 more
openaire   +2 more sources

Essential growth factor receptors for fibroblast homeostasis and activation: Fibroblast Growth Factor Receptor (FGFR), Platelet Derived Growth Factor Receptor (PDGFR), and Transforming Growth Factor β Receptor (TGFβR) [version 2; peer review: 2 approved]

F1000Research
Fibroblasts are cells of mesenchymal origin that are found throughout the body. While these cells have several functions, their integral roles include maintaining tissue architecture through the production of key extracellular matrix components, and ...
Matthew B. Buechler, Maye F. Cheng, Faizah S. Abdullah   +2 more
doaj   +1 more source