Results 21 to 30 of about 749,302 (341)

Stabilisation of Recombinant Human Basic Fibroblast Growth Factor (FGF-2) against Stressors Encountered in Medicinal Product Processing and Evaluation

open access: yesPharmaceutics, 2021
Basic fibroblast growth factor (FGF-2) is a highly labile protein with strong potential for tissue engineering. The aim of this study was to develop FGF-2 formulations that are stable against physical stressors encountered in pharmaceutical processing ...
Leah R. Benington   +3 more
doaj   +1 more source

Fibroblast growth factor 2 accelerates the epithelial–mesenchymal transition in keratinocytes during wound healing process

open access: yesScientific Reports, 2020
In the wound healing process, the morphology of keratinocytes at the wound edge temporarily changes to a spindle morphology, which is thought to occur due to an epithelial–mesenchymal transition (EMT).
Y. Koike   +3 more
semanticscholar   +1 more source

Fibroblast Growth Factor-2 (FGF-2). [PDF]

open access: yesScience-Business eXchange, 2009
Epileptogenesis and epilepsy progression are associated with rearrangements of neuronal circuits mediated by such processes as sprouting, neuronal cell death, and neurogenesis. These processes lead to hyperexcitability, spontaneous seizures, and/or worsening of seizure severity/frequency. Neurotrophic factors, and the Fibroblast Growth Factor-2 (FGF-2)
SIMONATO, Michele, ZUCCHINI, Silvia
openaire   +3 more sources

Circulating fibroblast growth factor-2 precipitates HIV nephropathy in mice

open access: yesDisease Models & Mechanisms, 2021
People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with HIVAN frequently show high plasma fibroblast growth factor-2 (FGF-2) levels; however, the role ...
Jharna R. Das   +5 more
doaj   +1 more source

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

open access: yesJournal of Neuroscience, 1997
Neurons and glia are generated throughout adulthood from proliferating cells in two regions of the rat brain, the subventricular zone (SVZ) and the hippocampus.
H. Kuhn   +8 more
semanticscholar   +1 more source

Incorporation of FGF-2 into Pharmaceutical Grade Fucoidan/Chitosan Polyelectrolyte Multilayers

open access: yesMarine Drugs, 2020
Biopolymer polyelectrolyte multilayers are a commonly studied soft matter system for wound healing applications due to the biocompatibility and beneficial properties of naturally occurring polyelectrolytes.
Natalie L. Benbow   +3 more
doaj   +1 more source

Intracellular trafficking of endogenous fibroblast growth factor‐2 [PDF]

open access: yesThe FEBS Journal, 2008
We have previously reported how the release of fibroblast growth factor‐2 (FGF‐2) is mediated by shed vesicles. In the present study, we address the question of how newly synthesized FGF‐2 is targeted to the budding vesicles. Considering that in vitro cultured Sk‐Hep1 hepatocarcinoma cells release FGF‐2 and shed membrane vesicles only when cultured in ...
Taverna Simona   +3 more
openaire   +4 more sources

Fibroblast Growth Factor-2-induced Signaling through Lipid Raft-associated Fibroblast Growth Factor Receptor Substrate 2 (FRS2) [PDF]

open access: yesJournal of Biological Chemistry, 2003
The plasma membrane is not homogeneous but contains specific subcompartments characterized by their unique lipid and protein composition. Based on their enrichment in various signaling molecules, these membrane microdomains are recognized to be sites of localized signal transduction for a number of extracellular stimuli.
Marc S, Ridyard, Stephen M, Robbins
openaire   +2 more sources

Long Pentraxin-3 Modulates the Angiogenic Activity of Fibroblast Growth Factor-2

open access: yesFrontiers in Immunology, 2018
Angiogenesis, the process of new blood vessel formation from pre-existing ones, plays a key role in various physiological and pathological conditions.
M. Presta   +3 more
semanticscholar   +1 more source

Fibroblast Growth Factor-2 Activates a Latent Neurogenic Program in Neural Stem Cells from Diverse Regions of the Adult CNS

open access: yesJournal of Neuroscience, 1999
During development of the mammalian brain, both neurons and glia are generated from multipotent neural stem cells. Although neurogenesis ceases in most areas at birth, stem cells continue to generate neurons within the subventricular zone and hippocampal
T. Palmer   +4 more
semanticscholar   +1 more source

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