Results 51 to 60 of about 1,606,538 (419)
Tumor Biology, 2017 In the past decades, the oncogenic role of fibroblast growth factor receptor 2 has been demonstrated in a number of cancer types. However, studies have reported contradictory findings concerning the correlation between fibroblast growth factor receptor 2
Gang Liu +3 more
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Branch Mode Selection during Early Lung Development [PDF]
PLoS Comput Biol 8(2): e1002377 (2012), 2012 Many organs of higher organisms, such as the vascular system, lung, kidney, pancreas, liver and glands, are heavily branched structures. The branching process during lung development has been studied in great detail and is remarkably stereotyped. The branched tree is generated by the sequential, non-random use of three geometrically simple modes of ...
arxiv +1 more source
A modeling approach to study the effect of cell polarization on keratinocyte migration [PDF]
PLoS ONE. 2015;10(2):e0117676, 2015 The skin forms an efficient barrier against the environment, and rapid cutaneous wound healing after injury is therefore essential. Healing of the uppermost layer of the skin, the epidermis, involves collective migration of keratinocytes, which requires coordinated polarization of the cells.
arxiv +1 more source
Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes. [PDF]
, 2011 INTRODUCTION: Cartilage degeneration driven by catabolic stimuli is a critical pathophysiological process in osteoarthritis (OA). We have defined fibroblast growth factor 2 (FGF-2) as a degenerative mediator in adult human articular chondrocytes ...
Chen, Di +6 more
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OncoTarget, 2016 Fibroblast growth factor (FGF) signaling is essential for normal and cancer biology. Mammalian FGF family members participate in multiple signaling pathways by binding to heparan sulfate and FGF receptors (FGFR) with varying affinities.
Mohamed R. Akl +9 more
semanticscholar +1 more source
Growth factors for clinical-scale expansion of human articular chondrocytes : Relevance for automated bioreactor systems [PDF]
, 2007 The expansion of chondrocytes in automated bioreactors for clinical use requires that a relevant number of cells be generated, starting from variable initial seeding densities in one passage and using autologous serum.
Andrea Barbero +12 more
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Fibroblast growth factor-2 alters the nature of extinction [PDF]
Learning & Memory, 2011 These experiments examined the effects of the NMDA-receptor (NMDAr) antagonist MK801 on reacquisition and re-extinction of a conditioned fear that had been previously extinguished before injection of fibroblast growth factor-2 (FGF2) or vehicle. Recent findings have shown that relearning and re-extinction, unlike initial learning and extinction, do not
Bronwyn M. Graham, Rick Richardson
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Neural Regeneration Research, 2022 The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited, especially in case of severe injury. This often leads to poor motor function and permanent disability.
Kamilla Faritovna Idrisova +11 more
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The discovery of angiogenic growth factors: the contribution of Italian scientists [PDF]
, 2014 Angiogenesis is regulated, under both physiological and pathological conditions, by numerous “non-classic” pro-angiogenic factors, including fibroblast growth factor-2 (FGF-2), vascular endothelial growth factor (VEGF), and placental growth factor (PlGF),
Domenico Ribatti
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Fibroblast growth factor 2 control of vascular tone [PDF]
Nature Medicine, 1998 Vascular tone control is essential in blood pressure regulation, shock, ischemia-reperfusion, inflammation, vessel injury/repair, wound healing, temperature regulation, digestion, exercise physiology, and metabolism. Here we show that a well-known growth factor, FGF2, long thought to be involved in many developmental and homeostatic processes ...
John J. Duffy +14 more
openaire +3 more sources