Results 31 to 40 of about 8,552 (153)
FGF23 in Chronic Kidney Disease: Bridging the Heart and Anemia
Cells, 2023 Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone produced mainly in osteocytes. In chronic kidney disease (CKD) FGF23 levels increase due to higher production, but also as the result of impaired cleavage and reduced excretion from the body ...
Andreja Figurek +2 more
doaj +1 more source
Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway
Chinese Medical Journal, 2023 . Background:. Congenital scoliosis (CS) is a complex spinal malformation of unknown etiology with abnormal bone metabolism. Fibroblast growth factor 23 (FGF23), secreted by osteoblasts and osteocytes, can inhibit bone formation and mineralization. This
Hongqi Zhang +8 more
doaj +1 more source
Fibroblast growth factor 23 (FGF23) and early chronic kidney disease in the elderly [PDF]
Nephrology Dialysis Transplantation, 2014 Better biomarkers of CKD reflecting responses to decreased glomerular filtration rate (GFR) are needed. We determined the value of estimated GFR (eGFR) as a threshold for the increase of plasma cFGF23 (C-terminal) and intact fibroblast growth factor-23 (iFGF23) (intact) concentrations in the course of chronic kidney disease (CKD) and compared this eGFR
Jerzy, Chudek +6 more
openaire +2 more sources
Serum Fibroblast Growth Factor 23 Level and Liver Fat Content in MAFLD: A Community-Based Cohort
Diabetes, Metabolic Syndrome and Obesity, 2021 Weijie Cao,* Yiting Xu,* Yun Shen, Yufei Wang, Xiaojing Ma, Yuqian Bao Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical ...
Cao W, Xu Y, Shen Y, Wang Y, Ma X, Bao Y
doaj
Radiology Case Reports, 2020 Tumor-induced osteomalacia (TIO) is a rare disease in which patients suffer from fractures and progressive disabling bone pain and muscle weakness.
Juan M. Colazo, BSc +3 more
doaj +1 more source
FGF23 promotes atrial fibrillation susceptibility through ETV1-dependent sodium channel regulation and calcium handling abnormalities. [PDF]
Exp PhysiolAbstract Fibroblast growth factor 23 (FGF23) is closely associated with atrial fibrillation (AF), yet whether it modulates sodium and calcium currents in atrial myocytes remains unclear. ETV1, a key transcription factor regulating atrial electrical conduction, might also be involved in FGF23‐mediated AF.
Yu Q +7 more
europepmc +2 more sources
Genetic Disorders of Calcium and Phosphorus Metabolism
Endocrines, 2022 In this review, we describe genetic mutations affecting metabolic pathways of calcium and phosphorus homeostasis. Calcium and phosphorus homeostasis has tight hormonal regulation by three major hormones: vitamin D, parathyroid hormone (PTH) and ...
Assia Miller +4 more
doaj +1 more source
Osteocytic FGF23 and Its Kidney Function
Frontiers in Endocrinology, 2020 Osteocytes, which represent up to 95% of adult skeletal cells, are deeply embedded in bone. These cells exhibit important interactive abilities with other bone cells such as osteoblasts and osteoclasts to control skeletal formation and resorption. Beyond
Rafiou Agoro +4 more
doaj +1 more source
Il Fibroblast Growth Factor-23 (FGF-23)
Giornale di Clinica Nefrologia e Dialisi, 2018 Negli ultimi due decenni, l'identificazione delle proprietà biologiche del Fibroblast Growth Factor 23 (FGF23) ha notevolmente ampliato le conoscenze sulla regolazione endocrina e paracrina dell'omeostasi dei fosfati e sulle relazioni intercorrenti tra ...
D. Rendina +4 more
doaj +1 more source
Phosphopenic form of osteomalacia in a patient with FGF23 producing tumor
Научно-практическая ревматология, 2022 Oncogenic osteomalacia is an orphan disease caused by the overproduction of fibroblast growth factor 23 (FGF23) in tumors, which leads to impaired bone matrix mineralization. Typical laboratory changes are hypophosphatemia, increased alkaline phosphatase,
A. S. Pushkareva +4 more
doaj +1 more source