Results 51 to 60 of about 665,368 (391)

Expression of the FGFR2c mesenchymal splicing variant in human keratinocytes inhibits differentiation and promotes invasion [PDF]

, 2018
The altered isoform switching of the fibroblast growth factor receptor 2 (FGFR2) and aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells is involved in cancer progression.
Anacker, Barbaresi, Barton, Belleudi, Boukamp, Brooks, Candi, Capone, Chaffer, Dotto, Feng, Gaggioli, Getsios, Goetz, Grose, Harmon, Haugsten, Ishiwata, Izar, Jones, Kawase, Matsuda, Oh, Oltean, Peng, Petiot, Pickard, Pickard, Purpura, Raffa, Ramsey, Ranieri, Ranieri, Shamir, Shih, Simpson, Truong, Turner, Warzecha, Warzecha, Yang, Ye, Zhang, Zhao   +43 more
core   +1 more source

Mechanism of Fibroblast Growth Factor in Alzheimer's Disease

Xiehe Yixue Zazhi
Alzheimer's disease(AD), the most common neurodegenerative disease, has shown an increasing incidence among younger people. With the onset of disease, most patients' cognitive function will show a progressive decline, bringing a heavy burden to the ...
WU Jiajing, LI Yan, LIANG Yuxia, HUA Huijuan, ZHAO Bo   +4 more
doaj   +1 more source

The association between fibroblast growth factor receptor 1 gene amplification and lung cancer: a meta-analysis

Archives of Medical Science, 2019
Introduction Identifying target oncogenic alterations in lung cancer represents a major development in disease management. We examined the association of fibroblast growth factor receptor 1 (FGFR1) gene amplification with pathological characteristics and
Jian-Long Miao, Jin-Hua Zhou, Jing-Jing Cai, Rui-Juan Liu   +3 more
doaj   +1 more source

Role of FGF System in Neuroendocrine Neoplasms: Potential Therapeutic Applications

Frontiers in Endocrinology, 2021
Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors originating from neuroendocrine cells dispersed in different organs. Receptor tyrosine kinases are a subclass of tyrosine kinases with a relevant role in several cellular processes ...
Giovanni Vitale, Giovanni Vitale, Alessia Cozzolino, Pasqualino Malandrino, Roberto Minotta, Giulia Puliani, Giulia Puliani, Davide Saronni, Antongiulio Faggiano, Annamaria Colao   +9 more
doaj   +1 more source

Tumor Necrosis Factor Receptor Mediates Fibroblast Growth Factor-Inducible 14 Signaling

Cellular Physiology and Biochemistry, 2017
Tumor necrosis factor (TNF)-related weak inducer of apoptosis (TWEAK) engages its sole receptor, fibroblast growth factor–inducible 14 (Fn14), which participates in various inflammatory and immunologic processes.
Xuening Wang, Shengxiang Xiao, Yumin Xia
doaj   +1 more source

Cytokine-related genes identified from the RIKEN full-length mouse cDNA data set [PDF]

, 2003
To identify novel cytokine-related genes, we searched the set of 60,770 annotated RIKEN mouse cDNA clones (FANTOM2 clones), using keywords such as cytokine itself or cytokine names (such as interferon, interleukin, epidermal growth factor, fibroblast ...
Brusic, V., GSL Members., Petrovsky, N., Pillai, R. S., Riken Ger Group, Schonbach, C., Silva, D. G.   +6 more
core   +1 more source

Fibroblast growth factor receptor fusions in cancer: opportunities and challenges

Journal of Experimental & Clinical Cancer Research, 2021
Fibroblast growth factors (FGFs) and their receptors (FGFRs) play critical roles in many biological processes and developmental functions. Chromosomal translocation of FGFRs result in the formation of chimeric FGFR fusion proteins, which often cause ...
Lingfeng Chen, Yanmei Zhang, Lina Yin, Binhao Cai, Ping Huang, Xiaokun Li, Guang Liang   +6 more
doaj   +1 more source

Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival

OncoTarget, 2016
Basal-like breast cancer is an aggressive tumor subtype with poor prognosis. The discovery of underlying mechanisms mediating tumor cell survival, and the development of novel agents to target these pathways, is a priority for patients with basal-like ...
Kai Hung Tiong, B. Tan, H. L. Choo, F. Chung, Ling-Wei Hii, Si-Hoey Tan, Nelson Tze Woei Khor, S. Wong, Sze-Jia See, Yuen-Fen Tan, R. Rosli, S. Cheong, C. Leong   +12 more
semanticscholar   +1 more source

Expression and localization of fibroblast growth factors and fibroblast growth factor receptors in the developing rat kidney [PDF]

Kidney International, 1999
Expression and localization of fibroblast growth factors and fibroblast growth factor receptors in the developing rat kidney.The permanent kidney, or metanephros, develops through a complex series of reciprocal inductive events and involves branching morphogenesis, tubulogenesis, angiogenesis, and tissue remodeling. Fibroblast growth factors (FGFs) are
John F. Bertram, John F. Bertram, Miriam Ford-Perriss, Miriam Ford-Perriss, Belinda Cancilla, Belinda Cancilla   +5 more
openaire   +3 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source