Journal of Medical Case Reports, 2023 Introduction Advances in the treatment of biliary tract cancer have been made possible through gains in genomic and epigenetic tumor understanding. The use of fibroblast growth factor receptor inhibitor has enabled significant clinical improvement in a ...
Andreas Edwin Juarso +2 more
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A Phosphoinositide 3-Kinase/Phospholipase Cgamma1 Pathway Regulates Fibroblast Growth Factor-Induced Capillary Tube Formation [PDF]
, 2009 Background: The fibroblast growth factors (FGFs) are key regulators of embryonic development, tissue homeostasis and tumour angiogenesis. Binding of FGFs to their receptor(s) results in activation of several intracellular signalling cascades including ...
Maffucci, Tania +40 more
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Fibroblast Growth Factor Receptor 1 Gene Amplification in Nonsmall Cell Lung Cancer
Chinese Medical Journal, 2016 Objective: To review the prevalence and prognostic significance of fibroblast growth factor receptor 1 (FGFR1) amplification and to establish an association between FGFR1 amplification and the clinical characteristics of nonsmall cell lung cancer (NSCLC).
Jian-Long Miao +3 more
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Advanced Science, 2021 AZD9291 can effectively prolong survival of non‐small cell lung cancer (NSCLC) patients. Unfortunately, the mechanism of its acquired drug resistance is largely unknown.
Yu Gu +7 more
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Biomedicines, 2021 Recently, non-alcoholic fatty liver disease (NAFLD) has emerged as a predominant health concern affecting approximately a quarter of the world’s population.
Sayali Bhave, Han Kiat Ho
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A role for fibroblast growth factor receptor 1 in the pathogenesis of Neisseria meningitidis [PDF]
Microbial Pathogenesis, 2018 Summary Neisseria meningitidis remains an important cause of human disease. It is highly adapted to the human host – its only known reservoir. Adaptations to the host environment include many specific interactions with human molecules including iron-binding proteins, components of the innate and ...
Sheyda Azimi +4 more
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Mammary tumorigenesis induced by fibroblast growth factor receptor 1 requires activation of the epidermal growth factor receptor [PDF]
Journal of Cell Science, 2011 Fibroblast growth factor receptor 1 (FGFR1) is an oncoprotein with known involvement in mammary tumorigenesis. To understand how FGFR1 signaling promotes mammary tumorigenesis, an inducible FGFR1 (iFGFR1) system was created previously. Previous studies have demonstrated that upon iFGFR1 activation in vivo, the epidermal growth factor (EGF) ligands ...
Lindsey K, Bade +4 more
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Immunohistochemical Expression of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptors 1 and 2 in the Pathogenesis of Lung Cancer [PDF]
Clinical Cancer Research, 2008 Abstract Purpose: To identify the patterns of protein expression of basic fibroblast growth factor (bFGF) and FGF receptors 1 and 2 in non-small cell lung carcinoma (NSCLC) and their role in the early pathogenesis of squamous cell carcinoma (SCC) of the lung.
Carmen, Behrens +6 more
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Presence and localization of a 30-kDa basic fibroblast growth factor-like protein in rodent testes [PDF]
, 1991 We have used a recently characterized rabbit antiserum against basic fibroblast growth factor (bFGF), which recognizes various forms of bFGF, to examine the presence and localization of bFGF in the testes of adult rats and mice and the 5-day-old rat.
Russell, J. T. +4 more
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The Impact of Oral Collagen on Histological Skin Aging Alterations in Female Albino Rats [PDF]
The Egyptian Journal of HistologyIntroduction: Chronological skin aging is a natural process marked by structural and functional alterations in the skin, resulting in diminished suppleness, the emergence of wrinkles, and a reduction in moisture.
hend elsaid +3 more
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