Results 31 to 40 of about 221,633 (255)

Prognostic role of fibroblast growth factor receptor 2 in human solid tumors: A systematic review and meta-analysis

open access: yesTumor Biology, 2017
In the past decades, the oncogenic role of fibroblast growth factor receptor 2 has been demonstrated in a number of cancer types. However, studies have reported contradictory findings concerning the correlation between fibroblast growth factor receptor 2
Gang Liu   +3 more
doaj   +1 more source

Biomarkers for gastric cancer: molecular classification revisited [PDF]

open access: yesPrecision and Future Medicine, 2017
Gastric cancer (GC) is one of the most common lethal cancer worldwide. In recent years, several new targeted therapeutic agents for the treatment of metastatic GC have been developed.
Jeeyun Lee, Kyoung-Mee Kim
doaj   +1 more source

Peritoneal Seeding Is More Common in Gastric Cancer Patients with FGFR2 Amplification or High Tumor Mutation Burden

open access: yesDiagnostics, 2022
Fibroblast growth factor receptor-2 (FGFR2) gene alterations have been identified in solid tumors. FGFR2 amplification is found in 2–9% of gastric carcinomas. We hypothesized that FGFR2 could be associated with peritoneal seeding and studied 360 advanced
Hyunjin Kim   +4 more
doaj   +1 more source

Immunohistochemical Expression of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptors 1 and 2 in the Pathogenesis of Lung Cancer [PDF]

open access: yesClinical Cancer Research, 2008
Abstract Purpose: To identify the patterns of protein expression of basic fibroblast growth factor (bFGF) and FGF receptors 1 and 2 in non-small cell lung carcinoma (NSCLC) and their role in the early pathogenesis of squamous cell carcinoma (SCC) of the lung.
Carmen, Behrens   +6 more
openaire   +2 more sources

FGFR2 (fibroblast growth factor receptor 2) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on FGFR2 (fibroblast growth factor receptor 2), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +2 more sources

F-Prostaglandin receptor regulates endothelial cell function via fibroblast growth factor-2

open access: yesBMC Cell Biology, 2010
Background Prostaglandin (PG) F2α is a key regulator of endometrial function and exerts its biological action after coupling with its heptahelical G protein-coupled receptor (FP receptor).
Jabbour Henry N   +3 more
doaj   +1 more source

Fibroblast Growth Factor Receptor 2 Overexpression in Multiple Familial Trichoepithelioma

open access: yesThe American Journal of Dermatopathology, 2023
Multiple familial trichoepithelioma (MFT) is included within a spectrum of genodermatosis with development of different benign adnexal neoplasms and mutation described in the cylindromatosis tumor suppressor (CYLD) gene.
Alicia Jiménez Antón   +4 more
openaire   +3 more sources

Role of ERK signaling in bladder urothelium in response to cyclophosphamide injury

open access: yesPhysiological Reports, 2022
Mice with inducible urothelial deletion of fibroblast growth factor receptor 2 (ShhCreERT2;Fgfr2Fl/Fl) injured with cyclophosphamide had aberrant basal cell endoreplication and poor regeneration.
Sridhar Tatarao Narla   +8 more
doaj   +1 more source

Comprehending fibroblast growth factor receptor like 1: Oncogene or tumor suppressor?

open access: yesCancer Treatment and Research Communications, 2021
Fibroblast Growth Factor Receptor Like 1 (FGFRL1) signaling has crucial role in a multitude of processes during genetic diseases, embryonic development and various types of cancer.
Aprajita, Rinu Sharma
doaj   +1 more source

Fibroblast Growth Factor 2 and Its Receptors in Bone Biology and Disease [PDF]

open access: yesJournal of the Endocrine Society, 2018
The fibroblast growth factor (FGF) regulatory axis is phylogenetically ancient, evolving into a large mammalian/human gene family of 22 ligands that bind to four receptor tyrosine kinases for a complex physiologic system controlling cell growth, differentiation, and metabolism. The tissue targets for the primary FGF function are mainly in cartilage and
Coffin, J Douglas   +2 more
openaire   +2 more sources

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