Calciphylaxis associated with the fibroblast growth factor receptor inhibitor erdafitinib [PDF]
Paul Macklis, MS +2 more
doaj +4 more sources
Reversible Retinopathy Associated with Fibroblast Growth Factor Receptor Inhibitor [PDF]
We present a case of reversible, pseudovitelliform lesions while a patient was taking pembrolizumab (PDL-1 inhibitor) and erdafitinib (pan-fibroblast growth factor receptor inhibitor) outside of clinical trial protocols. A 61-year-old patient with 3 days
Saagar N. Patel +2 more
doaj +2 more sources
Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer [PDF]
Several alterations in fibroblast growth factor receptor (FGFR) genes have been found in breast cancer; however, they have not been well characterized as therapeutic targets.
Turcin Saridogan +15 more
doaj +2 more sources
Trichiasis and dry eye syndrome in two patients on novel fibroblast growth factor receptor inhibitor therapies [PDF]
Purpose: Present two patients on two different novel FGFR inhibitors who developed trichiasis with dry eye syndrome. Observations: Two patients developed trichiasis and dry eye following FGFR inhibitor therapy.
Kyle B. Vinson +3 more
doaj +2 more sources
Fibroblast growth factor receptor inhibitor therapy induced calcinosis cutis treated with sodium thiosulfate [PDF]
Justin Qian, BS +7 more
doaj +2 more sources
Effects of FGFR inhibitor BGJ398 on cell biological behavior and drug resistance of leukemia cells [PDF]
Background and purpose: Fibroblast growth factor (FGF) family members can regulate cell proliferation, migration and differentiation and play an important role in tumorigenesis and metastasis. FGF receptor (FGFR) inhibitors have anti-tumor activity. This
张艳君 +3 more
doaj +2 more sources
Introduction Advances in the treatment of biliary tract cancer have been made possible through gains in genomic and epigenetic tumor understanding. The use of fibroblast growth factor receptor inhibitor has enabled significant clinical improvement in a ...
Andreas Edwin Juarso +2 more
doaj +1 more source
Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling
Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a single pass transmembrane protein that is reported to regulate several signaling pathways .
Shivangi Pande +2 more
doaj +1 more source
Thyroid dysfunction from inhibitor of fibroblast growth factor receptor
Background Thyroid dysfunction has not been previously reported in clinical trials of selective fibroblast growth factor receptor (FGFR) inhibitors including AZD4547.
Jeffrey Ahn +3 more
doaj +1 more source
The Role of Fibroblast Growth Factor Receptors Inhibitors in Bladder Cancer [PDF]
Dysregulation of fibroblast growth factor (FGF)-receptor (FGFR) signaling, which is implicated in various oncogenic processes, including tumor proliferation, survival, migration, invasion, and angiogenesis, has been identified as a critical factor in ...
Ho Kyung Seo +3 more
doaj +1 more source

