Results 31 to 40 of about 155,309 (252)
Gene expression of growth factor BMP15, GDF9, FGF2 and their receptors in bovine follicular cells
Revista Mvz Cordoba, 2018 Introduction. Growth and follicular maturation involve transformations of various components of the follicle, such as the oocyte, granulosa and techa cells.
Pablo S Reineri +5 more
doaj +1 more source
Receptor Specificity of the Fibroblast Growth Factor Family [PDF]
Journal of Biological Chemistry, 1996 Fibroblast growth factors (FGFs) are essential molecules for mammalian development. The nine known FGF ligands and the four signaling FGF receptors (and their alternatively spliced variants) are expressed in specific spatial and temporal patterns.
D M, Ornitz +7 more
openaire +2 more sources
Immunohistochemistry detection of Fibroblast growth factor3 (FGF3) in colorectal cancer tissue
Muthanna Journal of Pure ScienceColorectal cancer (CRC) is the second most common cancer that causes death worldwide. The exact cause remains elusive, but several factors affect the onset and progression, like genetic and environmental factors.
ALAA SAAD HASAN
doaj +1 more source
Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling
Cell Communication and Signaling, 2021 Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a single pass transmembrane protein that is reported to regulate several signaling pathways .
Shivangi Pande +2 more
doaj +1 more source
Basic fibroblast growth factor and its receptors in human embryonic stem cells.
Folia Histochemica et Cytobiologica, 2005 Human embryonic stem cells (hESCs) are pluripotent stem cells with long-lasting capacity to self-renew and differentiate into various cell types of endodermal, ectodermal or mesodermal origin.
Ales Hampl, Petr Dvorak
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F1000ResearchFibroblasts are cells of mesenchymal origin that are found throughout the body. While these cells have several functions, their integral roles include maintaining tissue architecture through the production of key extracellular matrix components, and ...
Matthew B. Buechler +2 more
doaj +1 more source
Characterization of the cholangiocarcinoma drug pemigatinib against FGFR gatekeeper mutants
Communications Chemistry, 2022 Pemigatinib is an FDA-approved drug for the treatment of cholangiocarcinoma, but while it is known to target fibroblast growth factor receptors, its mechanism of action is still not fully understood.
Qianmeng Lin +7 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Diagnostics, 2021 Congenital diaphragm hernia (CDH) is a congenital disease that occurs during prenatal development. Although the morbidity and mortality rate is rather significant, the pathogenesis of CDH has been studied insignificantly due to the decreased ...
Ricards Kaulins +3 more
doaj +1 more source