Fibroblasts as a ruler of the immune microenvironment: measurement and modulation in tissue homeostasis and disease [PDF]
Frontiers in ImmunologyFibroblasts, once considered merely passive structural components of tissues, are now recognized as dynamic regulators of the immune microenvironment.
Yanling Zhang +3 more
doaj +2 more sources
Nature Reviews Cancer, 2006 Tumours are known as wounds that do not heal - this implies that cells that are involved in angiogenesis and the response to injury, such as endothelial cells and fibroblasts, have a prominent role in the progression, growth and spread of cancers. Fibroblasts are associated with cancer cells at all stages of cancer progression, and their structural and
Raghu Kalluri
exaly +4 more sources
Cytotoxicity of PLGA-zinc oxide nanocomposite on human gingival fibroblasts [PDF]
Journal of Advanced Periodontology and Implant Dentistry, 2023 Background. Polylactic-co-glycolic acid and zinc oxide (PLGA-ZnO) nanocomposite has been investigated for its antibacterial properties, which could be beneficial for adding to wound dressings after periodontal surgery.
Asieh Mozaffari +3 more
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Adiponectin inhibits fibrosis of the palmar aponeurosis in Dupuytren’s contracture in male patients
Bone & Joint Research, 2023 Aims: Dupuytren’s contracture is characterized by increased fibrosis of the palmar aponeurosis, with eventual replacement of the surrounding fatty tissue with palmar fascial fibromatosis. We hypothesized that adipocytokines produced by adipose tissue in
Yoshiaki Yamanaka +7 more
doaj +1 more source
Effect of culture medium treated with non-thermal plasma energy on the growth and viability in-vitro of fibroblast cells from asian elephants (elephas maximus) [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 Non-thermal plasma (NTP) is being developed for a wide-range of medical applications such as improvement of wound healing, elimination of infective microorganisms, and treatment of cancer.
Sarisa KLINHOM +5 more
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Effect of Clinacanthus nutans leaf chloroform extract on reducing nitric oxide in fibroblasts
Scientific Dental Journal, 2023 Background: Clinacanthus nutans or dandang gendis is a plant that can be an effective herbal treatment for inflammation, in addition the Indonesian people are still looking for alternative treatments.
Erdita Hapsari +3 more
doaj +1 more source
Tumorigenic effects of human mesenchymal stromal cells and fibroblasts on bladder cancer cells
Frontiers in Oncology, 2023 BackgroundPatients with muscle-invasive bladder cancer face a poor prognosis due to rapid disease progression and chemoresistance. Thus, there is an urgent need for a new therapeutic treatment.
Lucie M. Frerichs +7 more
doaj +1 more source
A Fibroblast Is Not a Fibroblast Is Not a Fibroblast [PDF]
Journal of Investigative Dermatology, 2018 Fibrosis after injury is a huge public health concern, leading to morbidity, mortality, and expenditure of billions of health care dollars. Recent mouse studies have shown that dermal fibroblasts are heterogeneous. New research using single-cell RNA sequencing to identify major fibroblast populations in humans is paving the way to a better ...
Michael S, Hu +2 more
openaire +2 more sources
Nanomaterials, 2022 The extract of Teucrium marum L. (Lamiaceae) was obtained using the aerial parts of the plant, by means of a maceration process. Verbascoside, caffeic acids derivatives and flavonols were the main components contained in the extract as detected using ...
Mohammad Firoznezhad +9 more
doaj +1 more source
Differential effect of lactate on synovial fibroblast and macrophage effector functions
Frontiers in Immunology, 2023 IntroductionThe synovial membrane is the main site of inflammation in rheumatoid arthritis (RA). Here several subsets of fibroblasts and macrophages, with distinct effector functions, have been recently identified.
Valentina Pucino +13 more
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