Results 1 to 10 of about 988,166 (377)
Agent based modelling helps in understanding the rules by which fibroblasts support keratinocyte colony formation [PDF]
, 2008 Background: Autologous keratincoytes are routinely expanded using irradiated mouse fibroblasts and bovine serum for clinical use. With growing concerns about the safety of these xenobiotic materials, it is desirable to culture keratinocytes in media ...
A Macieira-Coelho +90 more
core +13 more sources
Fibroblasts mediate the angiogenesis of pheochromocytoma by increasing COX4I2 expression
Frontiers in Oncology, 2022 ObjectiveOur previous work found COX4I2 was associated with angiogenesis in pheochromocytoma. The purpose of this study was to explore the role of COX4I2 in regulating angiogenesis in pheochromocytoma.MethodsDistribution of COX4I2 was evaluated by scRNA ...
Yongxin Mao +10 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 Introduction: Antibiotics are often administered to patients perioperatively and have been shown to affect ROS production of nasal cells in vitro, but their effect in the setting of active wound healing remains unclear.
Michael Gouzos +5 more
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Adult mouse fibroblasts retain organ-specific transcriptomic identity
eLife, 2022 Organ fibroblasts are essential components of homeostatic and diseased tissues. They participate in sculpting the extracellular matrix, sensing the microenvironment, and communicating with other resident cells. Recent studies have revealed transcriptomic
Elvira Forte +13 more
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Frontiers in Bioengineering and Biotechnology, 2022 Interactions between fibroblasts and immune cells play an important role in tissue inflammation. Previous studies have found that eosinophils activated with interleukin-3 (IL-3) degranulate on aggregated immunoglobulin G (IgG) and release mediators that ...
Yuting Zeng +16 more
doaj +1 more source
Frontiers in Immunology, 2022 IL-1 plays a crucial role in triggering sterile inflammation following tissue injury. Although most studies associate IL-1 release by injured cells to the recruitment of neutrophils for tissue repair, the inflammatory cascade involves several molecular ...
Sevda Cordier-Dirikoc +11 more
doaj +1 more source
Quantification of cell contractile behavior based on non-destructive macroscopic measurement of tension forces on bioprinted hydrogel [PDF]
Journal of the mechanical behavior of biomedical materials, 2022,
134, pp.105365, 2023 Contraction assay based on surface measurement have been widely used to evaluate cell contractility in 3D models. This method is straightforward and requires no specific equipment, but it does not provide quantitative data about contraction forces generated by cells.
arxiv +1 more source
eLife, 2021 Mortality from breast cancer is almost exclusively a result of tumor metastasis, and lungs are one of the main metastatic sites. Cancer-associated fibroblasts are prominent players in the microenvironment of breast cancer.
Ophir Shani +15 more
doaj +1 more source
Immunity, Inflammation and Disease, 2022 Introduction Hypertrophic scar (HS), a fibroproliferative disorder of the skin with some tumor‐like properties, is closely related to dysregulated inflammation.
Yuanyuan Cai +6 more
doaj +1 more source
Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling [PDF]
Mathematical Medicine and Biology: A Journal of the IMA 38(1),
106-131 (2021), 2020 The electrical coupling between myocytes and fibroblasts and the spacial distribution of fibroblasts within myocardial tissues are significant factors in triggering and sustaining cardiac arrhythmias but their roles are poorly understood. This article describes both direct numerical simulations and an asymptotic theory of propagation and block of ...
arxiv +1 more source