Thyroid Cancer and Fibroblasts
Cancers, 2022 Thyroid cancer is the most common type of endocrine cancer, and its prevalence continue to rise. Non-metastatic thyroid cancer patients are successfully treated. However, looking for new therapeutic strategies is of great importance for metastatic thyroid cancers that still lead to death.
Angelica Avagliano +14 more
openaire +3 more sources
Inflammation and its resolution and the musculoskeletal system
Journal of Orthopaedic Translation, 2017 Inflammation, an essential tissue response to extrinsic/intrinsic damage, is a very dynamic process in terms of complexity and extension of cellular and metabolic involvement.
Jiri Gallo +3 more
doaj +1 more source
Photobiomodulation of human gingival fibroblasts with diode laser - A systematic review
Journal of Indian Society of Periodontology, 2022 Low-level laser therapy (LLLT) is being extensively studied in the field of periodontics as a noninvasive technique to achieve better results after nonsurgical and surgical therapy. However, there is a lack of definitive guidelines for the use of LLLT to
Purva Vijay Bakshi +2 more
doaj +1 more source
Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells. [PDF]
, 2015 The treatment of myocardial infarction is a major challenge in medicine due to the inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac fibroblasts into functional cardiomyocytes via the delivery of transcription factor ...
Kim, Hyun Jin +5 more
core +3 more sources
Alpha-Tocopherol Counteracts the Cytotoxicity Induced by Ochratoxin A in Primary Porcine Fibroblasts
Toxins, 2010 The aims of the current study were to determine the half-lethal concentration of ochratoxin A (OTA) as well as the levels of lactate dehydrogenase release and DNA fragmentation induced by OTA in primary porcine fibroblasts, and to examine the role of α ...
Eleonora Fusi +9 more
doaj +1 more source
Bioengineering Methods in MicroRNA-Mediated Direct Reprogramming of Fibroblasts Into Cardiomyocytes
Frontiers in Cardiovascular Medicine, 2021 Ischemic heart disease is the major cause of mortality worldwide. Despite the most recent pharmacological progresses, cardiac regeneration is yet not possible, and heart transplantation is the only therapeutic option for end-stage heart failure ...
Camilla Paoletti, Valeria Chiono
doaj +1 more source
Proliferative and inductive effects of Cyclosporine a on gingival fibroblast of child and adult
Dental Research Journal, 2013 Background: Gingival overgrowth is a serious side-effect that accompanies the use of Cyclosporin A (CsA). Up to 97% of the transplant recipient children, who were submitted to CsA therapy, have been reported to suffer from this side-effect.
Bahareh Nazemi Salman +3 more
doaj +1 more source
Bridging Insights From Lymph Node and Synovium Studies in Early Rheumatoid Arthritis
Frontiers in Medicine, 2022 Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology characterized by inflammation of the peripheral synovial joints leading to pannus formation and bone destruction.
Aoife M. O'Byrne +8 more
doaj +1 more source
Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis [PDF]
, 2016 Cancer-associated fibroblasts (CAF) remain a poorly characterized, heterogeneous cell population. Here we characterized two previously described tumor-promoting CAF sub-types, smooth muscle actin (SMA)-positive myofibroblasts and senescent fibroblasts ...
Brennan, PA +26 more
core +2 more sources
The FASEB Journal, 2023 AbstractG protein‐coupled receptors (GPCRs) are the largest and most diverse class of signaling receptors. GPCRs regulate many functions in the human body and have earned the title of “most targeted receptors”. About one‐third of the commercially available drugs for various diseases target the GPCRs.
Nidhi V. Dwivedi +6 more
openaire +3 more sources