Incorporation of Aloe vera extract in bacterial nanocellulose membranes
Nanocellulose (BNC) is a natural polymer produced by bacteria. Its structure has only glucose monomer, it has various properties such as high water holding capacity, unique nanostructure, high crystallinity and high mechanical strength.
Lya Piaia+4 more
doaj +1 more source
Impact of sequence variation in the ul128 locus on production of human cytomegalovirus in fibroblast and epithelial cells [PDF]
The human cytomegalovirus (HCMV) virion envelope contains a complex consisting of glycoproteins gH and gL plus proteins encoded by the UL128 locus (UL128L): pUL128, pUL130, and pUL131A.
A. J. Davison+87 more
core +2 more sources
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee+16 more
wiley +1 more source
Fluoride resistance capacity in mammalian cells involves complex global gene expression changes
Fluorine is a bone‐seeking element ubiquitously present in the environment and widely used in many oral hygiene products. In humans, excessive intake of fluoride may cause dental and skeletal fluorosis.
Shujun Ran+7 more
doaj +1 more source
Fibroblast mediated dynamics in diffusively uncoupled myocytes -- a simulation study using 2-cell motifs [PDF]
In healthy hearts myocytes are typically coupled to nearest neighbours through gap junctions. Under pathological conditions such as fibrosis, or in scar tissue, or across ablation lines myocytes can uncouple from their neighbours. Electrical conduction may still occur via fibroblasts that not only couple proximal myocytes but can also couple otherwise ...
arxiv
Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors. [PDF]
Despite several investigations, the transcriptional mechanisms that regulate the expression of both type I collagen genes (COL1A1 and COL1A2) in either physiological or pathological situations, such as scleroderma, are not completely known.
Beauchef, Gallic+11 more
core +2 more sources
Nitric Oxide Is Involved in Heavy Ion-Induced Non-Targeted Effects in Human Fibroblasts [PDF]
Previously, we investigated the dose response for chromosomal aberration (CA) for exposures corresponding to less than one particle traversal per cell nucleus by high energy and charge (HZE) particles, and showed that the dose responses for simple ...
Cucinotta, Francis A.+2 more
core +2 more sources
“There will be blood” from fibroblasts [PDF]
The blood system is continuously replenished from a rare population of hematopoietic stem cells (HSCs) that balance self-renewal and differentiation.1 It is believed that HSCs emerge during embryog...
Ihor R. Lemischka+2 more
openaire +3 more sources
Remodeling by fibroblasts alters the rate-dependent mechanical properties of collagen [PDF]
The ways that fibroblasts remodel their environment are central to wound healing, development of musculoskeletal tissues, and progression of pathologies such as fibrosis.
Babaei, B.+6 more
core +1 more source
Deciphering cancer fibroblasts [PDF]
In this issue of JEM, Raz et al. (https://doi.org/10.1084/jem.20180818) identify a subset of bone marrow–derived cells that uniquely promotes breast cancer angiogenesis and tumor growth. The existence of functional heterogeneity among stromal populations motivates further fundamental and therapeutic inquiries.
Giulia Biffi, David A. Tuveson
openaire +3 more sources