Results 1 to 10 of about 1,902,157 (395)

Association between noninvasive fibrosis markers and cardio-vascular organ damage among adults with hepatic steatosis [PDF]

, 2014
Evidence suggests that advanced fibrosis, as determined by the noninvasive NAFLD fibrosis score (NFS), is a predictor of cardiovascular mortality in individuals with ultrasonography-diagnosed NAFLD. Whether the severity of histology (i.e., fibrosis stage)
Fiorentino, Tv, Perticone, F, Perticone, M, Sciacqua, A, Sesti, G, Succurro, E   +5 more
core   +23 more sources

Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline

American Journal of Respiratory and Critical Care Medicine, 2022
Background This American Thoracic Society, European Respiratory Society, Japanese Respiratory Society, and Asociación Latinoamericana de Tórax guideline updates prior idiopathic pulmonary fibrosis (IPF) guidelines and addresses the progression of ...
G. Raghu, M. Rémy-Jardin, L. Richeldi, C. Thomson, Y. Inoue, T. Johkoh, M. Kreuter, D. Lynch, T. Maher, F. Martinez, M. Molina-Molina, J. Myers, A. Nicholson, C. Ryerson, M. Strek, L. Troy, M. Wijsenbeek, M. Mammen, Tanzib Hossain, B. Bissell, D. Herman, S. Hon, F. Kheir, Y. Khor, M. Macrea, K. Antoniou, Demosthenes Bouros, I. Buendía-Roldán, F. Caro, B. Crestani, L. Ho, J. Morisset, A. Olson, A. Podolanczuk, V. Poletti, M. Selman, Thomas J. Ewing, S. Jones, Shandra L. Knight, M. Ghazipura, K. Wilson   +40 more
semanticscholar   +1 more source

What Is Most Suitable for Children With Cystic Fibrosis—The Relationship Between Spirometry, Oscillometry, and Multiple Breath Nitrogen Washout

Frontiers in Pediatrics, 2022
IntroductionIn cystic fibrosis (CF), pathological lung changes begin early in life. The technological progress currently gives many diagnostic possibilities. However, pulmonary function testing in children remains problematic.ObjectivesOur study aimed to
Magdalena Postek, Magdalena Postek, Katarzyna Walicka-Serzysko, Katarzyna Walicka-Serzysko, Justyna Milczewska, Justyna Milczewska, Dorota Sands, Dorota Sands   +7 more
doaj   +1 more source

Scedosporium species and Lomentospora prolificans in Italian cystic fibrosis patients: prevalence and distribution in seven centers using a selective medium

Microbiologia Medica, 2021
Background and aims. Scedosporium species and Lomentospora prolificans are the filamentous fungi isolated more frequently from the cystic fibrosis (CF) lower airways, after Aspergillus fumigatus. Previous studies showed that, in CF patients, Scedosporium
Lisa Cariani, Arianna Biffi, Davide Guarneri, Antonio Teri, Daniela Girelli, Chiara Vignati, Patrizia Morelli, Silvia Campana, Daniela Dolce, Vita Dora Iula, Maria Rosaria Catania, Natalia Cirilli, Sara Rapagnani, Martina Rossitto, Ersilia Vita Fiscarelli   +14 more
doaj   +1 more source

Establishing CREATE: lessons learned in setting up a training environment for early-career researchers in respiratory medicine

BMC Medical Education, 2022
Background The purpose of the National Health and Medical Research Council Centre of Research Excellence in Pulmonary Fibrosis (CRE-PF) is to improve and extend the lives of patients living with pulmonary fibrosis through the development of a ...
Katherine Christian, Alison Hey-Cunningham, Tamera Corte, Nicole Goh, Jade Jaffar, Paul Reynolds, Alan Teoh, Lauren Troy   +7 more
doaj   +1 more source

The Diagnosis of Cystic Fibrosis in Adult Age. Data from the Italian Registry

Diagnostics, 2021
Cystic Fibrosis (CF) registries are an essential resource of epidemiological and clinical data. Although the median age at diagnosis is usually reported in the first months of life, a minority of individuals is diagnosed during adulthood. The aim of this
Rita Padoan, Serena Quattrucci, Annalisa Amato, Vincenzo Carnovale, Donatello Salvatore, Marco Salvatore, Giuseppe Campagna   +6 more
doaj   +1 more source

A small molecule high throughput screening platform to profile conformational properties of nascent, ribosome-bound proteins

Scientific Reports, 2022
Genetic mutations cause a wide spectrum of human disease by disrupting protein folding, both during and after synthesis. Transient de-novo folding intermediates therefore represent potential drug targets for pharmacological correction of protein folding ...
Hideki Shishido, Jae Seok Yoon, William R. Skach   +2 more
doaj   +1 more source

Kidney fibrosis: from mechanisms to therapeutic medicines

Signal Transduction and Targeted Therapy, 2023
Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a hallmark manifestation in different progressive CKD; However, at ...
Rong-shuang Huang, P. Fu, Liang Ma
semanticscholar   +1 more source

Association between Polyunsaturated Fatty Acid Profile and Bronchial Inflammation in Bronchiolitis Obliterans

Mediators of Inflammation, 2023
Introduction. Bronchiolitis obliterans (BO) is a chronic lung disease, which occurs after an insult to the lower airways, in particular after airway infections or after stem cell transplantation, and which results in persistent inflammation.
Silvija P. Jerkic, Laura Bächle, Ruth Pia Duecker, Lucia Gronau, Andreas G. Chiocchetti, Stefan Zielen, Ralf Schubert   +6 more
doaj   +1 more source

Fibrosis: Types, Effects, Markers, Mechanisms for Disease Progression, and Its Relation with Oxidative Stress, Immunity, and Inflammation

International Journal of Molecular Sciences, 2023
Most chronic inflammatory illnesses include fibrosis as a pathogenic characteristic. Extracellular matrix (ECM) components build up in excess to cause fibrosis or scarring.
S. Antar, Nada A. Ashour, Mohamed E. Marawan, A. Al-karmalawy   +3 more
semanticscholar   +1 more source