Results 111 to 120 of about 3,647 (206)

Quality control of fibrinogen secretion in the molecular pathogenesis of congenital afibrinogenemia [PDF]

, 2017
Congenital afibrinogenemia is a rare bleeding disorder characterized by the absence in circulation of fibrinogen, a hexamer composed of two sets of three polypeptides (Aα, Bβ and γ).
Caille, Dorothée, de Moerloose, Philippe, Di Sanza, Corinne, Meda, Paolo, Neerman-Arbez, Marguerite, Scheib, Holger, Vu, Dung   +6 more
core  

The cell biology of the Trichosporon-Host interaction [PDF]

, 2017
Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are ...
Akoumianaki, Alby, Aratani, Arendrup, Arikawa, Arts, Bentubo, Cheng, Childers, Chitasombat, Choi, Colombo, Cong, Crawford, da Silva Dantas, de Almeida Junior, de Almeida Junior, Di Bonaventura, Ene, Ene, Erwig, Fernandes, Figueiredo-Carvalho, Fonseca, Fontaine, Gacser, Garlanda, Gish, Gouba, Gravelat, Gresnigt, Higashino-Kameda, Hole, Iliev, Karashima, Kontoyiannis, Kronstad, Krysan, Lamas, Lanternier, Lee, Li, Lyman, Lyman, Marine, Moalli, Monari, Moyes, Moylett, Muranaka, Nosanchuk, Pande, Picard, Piccioni, Quintin, Reddy, Richardson, Rieber, Rodriguez-Tudela, Rohatgi, Saeed, Sandai, Sasaki, Saunders, Schwartz, Sokol, Sriswasdi, Sugita, Sugita, Sun, Suzuki, Taylor-Smith, Thywißen, Walsh, Walsh, Wynne, Yauch, Zaragoza, Zelante, Zhang, Zhang, Zhang   +81 more
core   +1 more source

Insufficient serum L-ficolin is associated with disease presence and extent of pulmonary Mycobacterium avium complex disease

Respiratory Research, 2019
Background The incidence of infectious disease caused by nontuberculous mycobacteria is increasing worldwide. Pulmonary Mycobacterium avium complex (MAC) disease is difficult to treat with chemotherapy, and its mechanism of infection, infection route ...
Tomofumi Kobayashi, Koji Kuronuma, Atsushi Saito, Kimiyuki Ikeda, Shigeru Ariki, Atsushi Saitou, Mitsuo Otsuka, Hirofumi Chiba, Satoshi Takahashi, Motoko Takahashi, Hiroki Takahashi   +10 more
doaj   +1 more source

H-Ficolin

, 2013
H-ficolin is a serum lectin synthesized (as a ~34 kDa polypeptide) predominantly by the liver and lung tissues and is one of the soluble pattern recognition receptors of the innate immune system. It is structurally similar to L- and M- ficolins, but is different in its tissue expression and binding affinities to pathogenic ligands.
Chandrasekhar, Anjana, Dinasarapu, Ashok Reddy, Cedzynski, Maciej, Subramaniam, Shankar   +3 more
openaire   +1 more source

Ficolin-2 levels and FCN2 haplotypes influence hepatitis B infection outcome in Vietnamese patients.

PLoS ONE, 2011
Human Ficolin-2 (L-ficolins) encoded by FCN2 gene is a soluble serum protein that plays an important role in innate immunity and is mainly expressed in the liver.
Tong V Hoang, Nguyen L Toan, Le H Song, Eman Abou Ouf, C-Thomas Bock, Peter G Kremsner, Jürgen F J Kun, T P Velavan   +7 more
doaj   +1 more source

Lectin-complement pathway molecules are decreased in patients with cirrhosis and constitute the risk of bacterial infections [PDF]

, 2021
Antal-Szalmás, Péter, Dinya, Tamás, Földi, Ildikó, Papp, Mária, Sipeki, Nóra, Tornai, Dávid, Tornai, István, Tornai, Tamás István, Vitális, Zsuzsanna   +8 more
core   +1 more source

L-Ficolin

, 2013
L-ficolin is a serum lectin synthesized (as a ~37 kDa polypeptide) predominantly by the liver, and is one of the key molecules of the innate immune system. It has an amino (N)-terminal cysteine-rich region, a middle stretch of a collagen-like sequence, and a fibrinogen-like domain in the carboxy (C)-terminus.
Chandrasekhar, Anjana, Dinasarapu, Ashok Reddy, Thiel, Steffen, Subramaniam, Shankar   +3 more
openaire   +1 more source

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats.

PLoS ONE, 2015
The complement system has been increasingly recognized to play a pivotal role in a variety of inflammatory and autoimmune diseases. Consequently, therapeutic modulators of the classical, lectin and alternative pathways of the complement system are ...
Julia A Sharp, Pamela S Hair, Haree K Pallera, Parvathi S Kumar, Clifford T Mauriello, Julius O Nyalwidhe, Cody A Phelps, Dalnam Park, Nicole M Thielens, Stephen M Pascal, Waldon Chen, Diane M Duffy, Frank A Lattanzio, Kenji M Cunnion, Neel K Krishna   +14 more
doaj   +1 more source

The Primate Ficolins [PDF]

, 2010
Ficolins are pattern recognition molecules that share structural similarities with mannose-binding lectin (MBL), whose key function is to recognize carbohydrates on microorganisms or epitopes on dying host cells and subsequently are capable of activating the complement system, through the lectin pathway.
openaire  

Biofilm Formation Induces C3a Release and Protects Staphylococcus epidermidis from IgG and Complement Deposition and from Neutrophil-Dependent Killing [PDF]

, 2017
BackgroundBiofilm formation is considered to be an important virulence factor of the opportunistic pathogen Staphylococcus epidermidis. We hypothesized that biofilm formation could interfere with the deposition of immunoglobulins and complement on the ...
Birkenstock, Timo A., Götz, Friedrich, Kristian, Sascha A., Landmann, Regine, Mack, Dietrich, Sauder, Ursula   +5 more
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