Results 101 to 110 of about 3,647 (206)
Differential Role of the Lectin Pathway of Complement Activation in Susceptibility to Neonatal Sepsis [PDF]
, 2017 Background. The incidence of bacterial sepsis during the neonatal period is high. Mannan-binding lectin (MBL), L-ficolin, and H-ficolin recognize microorganisms and activate the complement system viaMBL-associated serine proteases (MASPs).
Boillat, Colette +8 more
core
Complement activation and its prognostic role in post-cardiac arrest patients [PDF]
, 2014 Cardiac arrest causes generalized ischemia/hypoxia, and subsequent resuscitation inflicts reperfusion injury, the pathology of which is not fully understood.
Bisschops +17 more
core +1 more source
Food Science &Nutrition, Volume 14, Issue 1, January 2026.This study combined network pharmacology, molecular docking, and in vitro (HepG2) and in vivo (T2DM mice) experiments to investigate sinapine's effect on insulin resistance. Sinapine was found to modulate the IRS1–PI3K–AKT–GSK3β–GS pathway. In vitro, sinapine improved glucose uptake, enhanced glycogen synthesis, and reduced lipogenesis and ROS. In vivo,
Tiancheng Xing +9 more
wiley +1 more source
PLoS ONE, 2010 The complement system is the main arm of the vertebrate innate immune system against pathogen infection. For the protozoan Trypanosoma cruzi, the causative agent of Chagas disease, subverting the complement system and invading the host cells is crucial ...
Igor Cestari, Marcel I Ramirez
doaj +1 more source
Polymorphism in ficolin-1 (FCN1) gene is associated with an earlier onset of type 1 diabetes mellitus in children and adolescents from northeast Brazil [PDF]
, 2016 10siFicolins are innate immune proteins able to activate the complement system by the lectin pathway. Single nucleotide polymorphisms (SNPs) of FCN1 and FCN2 genes, encoding for ficolin 1 and 2, have been related to the susceptibility to infectious and ...
GLAUCIA ALYNE NUNES DE LACERDA +9 more
core +1 more source
Specific binding of L-ficolin and H-ficolin to apoptotic cells leads to complement activation
Immunobiology, 2005 The serum lectins mannose-binding lectin (MBL), L-ficolin, and H-ficolin are recognition molecules in the lectin complement pathway, which play an important role in innate immunity. To assess involvement of the lectin pathway in the clearance of apoptotic cells, we used flow cytometry to quantify binding of MBL, L-ficolin, and H-ficolin to apoptotic ...
Mikio, Kuraya +4 more
openaire +2 more sources
Inherited deficiency of the initiator molecules of the lectin-complement pathway [PDF]
, 2010 Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)The complement system is an important immune system. Its activation results in membranolytic elimination of microbes and opsonization.
Björn Rúnar Lúðvíksson +1 more
core
Innate immunity and neuroinflammation [PDF]
, 2013 Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core +3 more sources
An updated molecular basis for mussel immunity [PDF]
, 2015 Non-self recognition with the consequent tolerance or immune reaction is a crucial process to succeed as living organisms. At the same time the interactions between host species and their microbiome, including potential pathogens and parasites ...
Gerdol, Marco, Venier, Paola
core +1 more source
Frontiers in Immunology, 2018 The complement system has moved into the focus of drug development efforts in the last decade, since its inappropriate or uncontrolled activation has been recognized in many diseases.
József Dobó +2 more
doaj +1 more source