Results 81 to 90 of about 3,647 (206)

Properdin and factor H: Opposing players on the alternative complement pathway "see-saw" [PDF]

, 2013
This article has been made available through the Brunel Open Access Publishing Fund.Properdin and factor H are two key regulatory proteins having opposite functions in the alternative complement pathway.
Abdul-Aziz, M, Kishore, U, Kouser, L, Nayak, A, Sim, RB, Stover, CM   +5 more
core   +1 more source

Yersinia enterocolitica O:3 Outer Membrane Vesicles as a Platform for Complement Activation

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
Basic characteristics and biological activity of outer membrane vesicles (OMVs) secreted by Yersinia enterocolitica O:3 (YeO3), depending on LPS chemotype and growth temperature. ABSTRACT Lipopolysaccharide (LPS) is the major component of the outer membrane vesicles (OMVs) of Gram‐negative bacteria.
Cédric Battaglino, Iryna Bodnaruk, Paula Czyszczoń, Mikael Skurnik, Beata Filip‐Psurska, Dariusz Jarych, Anna Maciejewska, Mariusz Gadzinowski, Kamil Malik, Izabela Potocka, Paweł Migdał, Roksana Kruszakin, Maciej Cedzyński, Katarzyna Kasperkiewicz, Jolanta Lukasiewicz, Anna S. Świerzko   +15 more
wiley   +1 more source

SALSA: a regulator of the early steps of complement activation on mucosal surfaces

Frontiers in Immunology, 2016
Complement is present mainly in blood. However, following mechanical damage or inflammation, serous exudates enter the mucosal surfaces. Here the complement proteins interact with other endogenous molecules to keep microbes from entering the parenteral ...
Martin eReichhardt, Seppo eMeri
doaj   +1 more source

Proteomic Profiling of Human Extracellular Vesicles Reveals Diagnostic Biomarkers for Colon Adenocarcinoma

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
Proteomic profiling of tissue explant‐ and plasma‐derived extracellular vesicles identified colon adenocarcinoma‐associated and healthy‐associated EV proteins. A 10‐protein EV panel enabled highly sensitive blood‐based detection of colon adenocarcinoma, showed marked postoperative changes, and retained performance in an independent validation cohort ...
Yura Seo, Yoon Dae Han, Linda Bojmar, Kyung‐A Kim, Yurin Seo, Taeyul K. Kim, Suho Lee, Yeleem Kim, Hye Bin Choi, Yujin H. Lim, Chae Hyun Kim, Alexander Sandberg, Chuanwen Fan, Pernille Lauritzen, Henrik Molina, Christopher Peralta, Jacob B. Geri, Colin Burdette, Dai Hoon Han, Heon Yung Gee, Insuk Lee, Jeon‐Soo Shin, Hyunwook Kim, Leon Li, Gabriel C. Tobias, Inbal Wortzel, Sang Joon Shin, Hyo‐Il Jung, Min Goo Lee, Soonmyung Paik, Robert E. Schwartz, Joong Bae Ahn, David Lyden, Han Sang Kim   +33 more
wiley   +1 more source

The Third Dimension of Reading the Sugar Code by Lectins [PDF]

, 2013
Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages ...
André, Sabine, Gabius, Hans-Joachim, Murphy, Paul V.   +2 more
core   +3 more sources

Therapeutic Potential of Lentiviral miR‐200a Mimics in Regulating Fibrinolysis and EMT Markers During Pulmonary Fibrosis

FASEB BioAdvances, Volume 8, Issue 4, April 2026.
The graphical abstract contrasts normal and fibrotic lungs, illustrating how miR‐200a mimics suppress PAI‐1 and EMT markers, restore fibrinolysis, and reduce MMP‐driven ECM deposition. This schematic highlights the therapeutic potential of miR‐200a in mitigating pulmonary fibrosis progression.
T. M. Jeena, C. Rakshitha, Akarsha B. Jain, Vaishnavi, Fathima Razana, Aleena Varughese, M. Fathimath Muneesa, Yashodhar P. Bhandary   +7 more
wiley   +1 more source

The interaction pattern of murine serum ficolin-A with microorganisms.

PLoS ONE, 2012
The ficolins are soluble pattern recognition molecules in the lectin pathway of complement, but the spectrum and mode of interaction with pathogens are largely unknown.
Tina Hummelshøj, Ying Jie Ma, Lea Munthe-Fog, Thomas Bjarnsholt, Claus Moser, Mikkel-Ole Skjoedt, Luigina Romani, Teizo Fujita, Yuichi Endo, Peter Garred   +9 more
doaj   +1 more source

Glyco-biomarkers: Potential determinants of cellular physiology and pathology [PDF]

, 2008
Once dismissed as just the icing on the cake, sugar molecules are emerging as vital components in life’s intricate machinery. Our understanding of their function within the context of the proteins and lipids to which they are attached has matured rapidly,
Alavi, A, Axford, JS
core   +2 more sources

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation [PDF]

, 2015
MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly.
Heumüller, Stefanie E, Holm, Anne T, Holmskov, Uffe, Moeller, Jesper B, Moestrup, Soren K, Pilecki, Bartosz, Schlosser, Anders, Sengle, Gerhard, Sorensen, Grith L, Wallis, Russell, Wohl, Alexander P, Zuk, Alexandra V   +11 more
core   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source