Results 61 to 70 of about 3,647 (206)
PLoS ONE, 2016 Despite recombinant protein technology development, proteins isolated from natural sources remain important for structure and activity determination. Ficolins represent a class of proteins that are difficult to isolate.
Aleksandra Man-Kupisinska +6 more
doaj +1 more source
PATTERN RECOGNITION RECEPTORS AND THEIR ROLE IN IMMUNOPATHOGENESIS OF PNEUMONIA (LITERATURE REVIEW)
Медицинская иммунология, 2019 Non-specific binding of antigens is provided by the so-called pattern recognition receptors (PRR). PRR can be located on the cell membrane, in the cytosol and in soluble form in the blood serum.
Maxim Olegovich Zolotov +2 more
doaj +1 more source
Circulating ficolin-2 and ficolin-3 in normal pregnancy and pre-eclampsia
Clinical and Experimental Immunology, 2012 Summary Ficolins are soluble molecules of the innate immune system that recognize carbohydrate molecules on microbial pathogens, apoptotic and necrotic cells. They act through two distinct routes: initiating the lectin pathway of complement activation and mediating a primitive opsonophagocytosis.
Halmos, Amrita +5 more
openaire +4 more sources
Experimental Hematology & Oncology, 2021 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) is a life-threatening syndrome that occurs in adult and pediatric patients after hematopoietic stem cell transplantation.
Eleni Gavriilaki +6 more
doaj +1 more source
The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells [PDF]
, 2016 Pentraxin 3 (PTX3) is a fluid-phase pattern recognition receptor of the humoral innate immune system with ancestral antibody-like properties but unknown antibody-inducing function.
A. Cooper Walland +24 more
core +3 more sources
H-ficolin (ficolin-3) concentrations and FCN3 gene polymorphism in neonates
Immunobiology, 2012 Serum H-ficolin (ficolin-3) concentrations (n=613) and FCN3 genotypes (n=529) from a large group of neonates are presented. Both pre-term deliveries and low birthweight (independently of gestational age) were significantly associated with low H-ficolin concentrations but not with heterozygosity for the FCN3 1637delC frameshift mutation. The presence of
Mateusz, Michalski +12 more
openaire +2 more sources
Mannose binding lectin is required for alphavirus-induced arthritis/myositis [PDF]
, 2015 Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Blevins, Lance K. +10 more
core +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, EarlyView.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 5, May 2026.ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein +8 more
wiley +1 more source
The Role of Humoral Innate Immunity in Hepatitis C Virus Infection
Viruses, 2012 Infection with Hepatitis C Virus (HCV) causes chronic disease in approximately 80% of cases, resulting in chronic inflammation and cirrhosis. Current treatments are not completely effective, and a vaccine has yet to be developed.
Richard A. Urbanowicz +2 more
doaj +1 more source