Results 51 to 60 of about 3,647 (206)
Pentraxins in Complement Activation and Regulation
Frontiers in Immunology, 2018 The complement is the first line of immune defense system involved in elimination of invading pathogens and dying host cells. Its activation is mainly triggered by immune complexes or pattern recognition molecules (PRMs) upon recognition against non-self
Ying Jie Ma, Peter Garred
doaj +1 more source
Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults
Scientific Reports, 2020 We investigated clinical associations of ficolins and mannose-binding lectin (MBL) in 157 patients suffering from acute myeloid leukaemia (AML). Concentrations of ficolin-1, ficolin-2, ficolin-3 and MBL (before chemotherapy) in serum were determined as ...
Anna Sokołowska +15 more
doaj +1 more source
The serum opsonin L-ficolin is detected in lungs of human transplant recipients following fungal infections and modulates inflammation and killing of Aspergillus fumigatus. [PDF]
, 2015 BACKGROUND: Invasive aspergillosis (IA) is a life-threatening systemic fungal infection in immunocompromised individuals that is caused by Aspergillus fumigatus. The human serum opsonin, L-ficolin, has been observed to recognize A.
Abdolrasouli, A +6 more
core +2 more sources
Streptococcus pneumoniae interactions with the complement system
Frontiers in Cellular and Infection Microbiology, 2022 Host innate and adaptive immunity to infection with Streptococcus pneumoniae is critically dependent on the complement system, demonstrated by the high incidence of invasive S.
Eliza Gil +2 more
doaj +1 more source
The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer
Frontiers in Immunology, 2019 The innate immune system comprises a cellular and a humoral arm. Humoral pattern recognition molecules include complement components, collectins, ficolins, and pentraxins.
Andrea Doni +10 more
doaj +1 more source
Systems Biology Modeling of the Complement System Under Immune Susceptible Pathogens
Frontiers in Physics, 2021 The complement system is assembled from a network of proteins that function to bring about the first line of defense of the body against invading pathogens.
Nehemiah T. Zewde +4 more
doaj +1 more source
L-ficolin and H-ficolin in patients with Familial Mediterranean fever [PDF]
Pediatric Rheumatology, 2015 In the present study we performed comparative determination of the blood levels of L-ficolin and H-ficolin, opsonins and the initial components of the complement lectin pathway, in patients with Familial Mediterranean fever (FMF) in attack and attack-free periods and healthy subjects.
Mkrtchyan, G, Boyajyan, A
openaire +1 more source
Blood Collection Tubes Influence Serum Ficolin-1 and Ficolin-2 Levels [PDF]
Clinical and Vaccine Immunology, 2013 ABSTRACTThe ficolins are members of a recently discovered family of host innate opsonins that can activate the lectin pathway of complement. The ficolins bind many ligands, although they are typically described as binding acetylated sugars. Ficolin-1 (M-ficolin) and ficolin-2 (L-ficolin) are known to bindStreptococcus pneumoniaeserotypes 19C and 11A ...
Allison M, Brady +3 more
openaire +2 more sources
Human Lectins and Their Roles in Viral Infections
Molecules, 2015 Innate recognition of virus proteins is an important component of the immune response to viral pathogens. A component of this immune recognition is the family of lectins; pattern recognition receptors (PRRs) that recognise viral pathogen-associated ...
Christopher P. Mason, Alexander W. Tarr
doaj +1 more source
Chronic Diseases and Translational Medicine, EarlyView.High‐resolution single‐cell atlas of normal gastric tissue, primary gastric cancer, and metastatic lesions. (A) Schematic diagram of experimental design. (B) Bar plot for qualified cell numbers in each lesion. (C) Cells annotation by canon markers for all cells. (D) Bubble chart for canon marker genes for each cell subtype.
Min Sun +3 more
wiley +1 more source