Results 71 to 80 of about 1,942 (166)

Landscape of Immune Remodeling and NAP1L1‐Driven Epithelial Reprogramming in Gastric Cancer Metastasis

Chronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 126-138, June 2026.
High‐resolution single‐cell atlas of normal gastric tissue, primary gastric cancer, and metastatic lesions. (A) Schematic diagram of experimental design. (B) Bar plot for qualified cell numbers in each lesion. (C) Cells annotation by canon markers for all cells. (D) Bubble chart for canon marker genes for each cell subtype.
Min Sun, Yuanzhi Wang, Yuqing Zhang, Xiaojuan Wang   +3 more
wiley   +1 more source

Lectin Pathway Components And Its Transfer From Blood To Cerebrospinal Fluid

Revista Cubana de Investigaciones Biomédicas, 2019
Introduction: Defining mechanisms governing the diffusion from blood to cerebrospinal fluid is central to understanding immune function in the central nervous system. OBJECTIVE.
Alejandro Ramos-Robledo, Christian Meijides Mejías, José Alejandro Rodríguez Pérez, Alejandro Mirabal Viel, Vanessa Pérez del Vallín, Alberto Juan Dorta Contreras   +5 more
doaj  

Advancing IBD Management: A Literature Review on the Role of Non‐Invasive Blood‐Based Biomarkers in Predicting and Assessing Pharmacodynamic Response to Treatment

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein, Li Xi, Rathi D. Ryan, Zhan (Harold) Ye, Nessy Tania, Yamato Sano, Joshua Varghese, Diogo Branquinho, Anna Sapone   +8 more
wiley   +1 more source

Innate Immunity and Microbial Recognition in Reproduction: From Barrier Defense to Maternal–Fetal Tolerance

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao, Li Zou, Yao Yao, Changling Liu   +3 more
wiley   +1 more source

Pattern recognition receptors and their role in immunopathogenesis of pneumonia

Медицинская иммунология
Non-specific binding of antigens is provided by the so-called pattern recognition receptors (PRR) that may be located on the cell membrane, in the cytosol, or, as soluble molecules in the blood serum.
M. O. Zolotov, N. B. Migacheva, A. V. Lyamin   +2 more
doaj   +1 more source

The Emerging Role of Complement Lectin Pathway in Trypanosomatids: Molecular Bases in Activation, Genetic Deficiencies, Susceptibility to Infection, and Complement System-Based Therapeutics

The Scientific World Journal, 2013
The innate immune system is evolutionary and ancient and is the pivotal line of the host defense system to protect against invading pathogens and abnormal self-derived components. Cellular and molecular components are involved in recognition and effector
Ingrid Evans-Osses, Iara de Messias-Reason, Marcel I. Ramirez   +2 more
doaj   +1 more source

Genetic Susceptibility to Rheumatic Heart Disease: A Narrative Literature Review Highlighting Evidence From African Populations and Research Gaps in Sudan

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Rheumatic heart disease (RHD) remains a significant public health burden in low‐ and middle‐income countries, particularly in sub‐Saharan Africa. Although socioeconomic factors contribute to disease persistence, genetic susceptibility plays a critical role in determining progression from Group A Streptococcal infection to ...
Hussam Alkhalifamohamed, Waleed M. A. Jebreel, Mohamed Elhassan, Sulafa K. M. Ali   +3 more
wiley   +1 more source

Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men

Scientific Reports, 2017
Insulin resistance is associated with high circulating level of complement factor C3. Animal studies suggest that improper complement activation mediates high-fat-diet-induced insulin resistance.
Caroline Foghmar, Charlotte Brøns, Katrine Pilely, Allan Vaag, Peter Garred   +4 more
doaj   +1 more source

New Insights Into the Stromal‐Immune Crosstalk During IBD: GLIS3 as a Potential Marker for the Inflammation‐To‐Fibrosis Transition

JCC Plus, Volume 1, Issue 4, July 2026.
Gaia Zanella
wiley   +1 more source

Yersinia enterocolitica O:3 Outer Membrane Vesicles as a Platform for Complement Activation

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
Basic characteristics and biological activity of outer membrane vesicles (OMVs) secreted by Yersinia enterocolitica O:3 (YeO3), depending on LPS chemotype and growth temperature. ABSTRACT Lipopolysaccharide (LPS) is the major component of the outer membrane vesicles (OMVs) of Gram‐negative bacteria.
Cédric Battaglino, Iryna Bodnaruk, Paula Czyszczoń, Mikael Skurnik, Beata Filip‐Psurska, Dariusz Jarych, Anna Maciejewska, Mariusz Gadzinowski, Kamil Malik, Izabela Potocka, Paweł Migdał, Roksana Kruszakin, Maciej Cedzyński, Katarzyna Kasperkiewicz, Jolanta Lukasiewicz, Anna S. Świerzko   +15 more
wiley   +1 more source