Results 71 to 80 of about 3,647 (206)

Ficolins and the Fibrinogen-like Domain

Immunobiology, 1998
Ficolins are a group of proteins containing collagen-like and fibrinogen-like (FBG) sequences and they have a similar overall structure to C1q and the collectins. There are two types of ficolin in man: L-ficolin and M-ficolin. L-ficolin is synthesized in the liver and secreted into the plasma.
Lu, J., Le, Y.
openaire   +2 more sources

Innate Immunity and Microbial Recognition in Reproduction: From Barrier Defense to Maternal–Fetal Tolerance

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao, Li Zou, Yao Yao, Changling Liu   +3 more
wiley   +1 more source

The Interactions of Parasite Calreticulin With Initial Complement Components: Consequences in Immunity and Virulence

Frontiers in Immunology, 2020
Because of its capacity to increase a physiologic inflammatory response, to stimulate phagocytosis, to promote cell lysis and to enhance pathogen immunogenicity, the complement system is a crucial component of both the innate and adaptive immune ...
Galia Ramírez-Toloza, Lorena Aguilar-Guzmán, Carolina Valck, Viviana P. Ferreira, Arturo Ferreira   +4 more
doaj   +1 more source

Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin [PDF]

, 2009
Udgivelsesdato: 2009-Sep-15Chitin is a highly acetylated compound and the second most abundant biopolymer in the world next to cellulose. Vertebrates are exposed to chitin both through food ingestion and when infected with parasites, and fungi and chitin
Holmskov, Uffe, Moeller, Jesper B, Moestrup, Søren K, Mollenhauer, Jan, Nielsen, Ole, Schlosser, Anders, Thomsen, Theresa, Tornøe, Ida   +7 more
core   +1 more source

M-ficolin in children with cancer

Immunobiology, 2011
M-ficolin (ficolin-1) is a complement-activating pattern-recognition molecule structurally related to mannan-binding lectin. It is produced by monocytes and neutrophils, and is found in serum. Its biological role is largely unknown. We assessed M-ficolin concentration in serum from pediatric cancer patients.
Schlapbach, Luregn J., Thiel, Steffen, Aebi, Christoph, Hirt, Andreas, Leibundgut, Kurt, Jensenius, Jens C., Ammann, Roland A.   +6 more
openaire   +4 more sources

Association of Ficolin-2 Serum Levels and FCN2 Genetic Variants with Indian Visceral Leishmaniasis.

PLoS ONE, 2015
BackgroundVisceral leishmaniasis (VL), one of the neglected tropical diseases, is endemic in the Indian subcontinent. Ficolins are circulating serum proteins of the lectin complement system and involved in innate immunity.MethodsWe have estimated ficolin-
Anshuman Mishra, Justin S Antony, Pandarisamy Sundaravadivel, Hoang Van Tong, Christian G Meyer, Reshma D Jalli, Thirumalaisamy P Velavan, Kumarasamy Thangaraj   +7 more
doaj   +1 more source

Complement in the homeostatic and ischemic brain [PDF]

, 2015
The complement system is a component of the immune system involved in both recognition and response to pathogens, and it is implicated in an increasing number of homeostatic and disease processes. It is well documented that reperfusion of ischemic tissue
Aivazian, Akita, Alexander, Amara, Arumugam, Atkinson, Austen, Barber, Barber, Bednar, Beek, Bellander, Benard, Benard, Benoit, Boos, Busche, Carmichael, Carmichael, Carmichael, Cavusoglu, Cervera, Chu, Cojocaru, Costa, Cowell, Crane, Cudrici, Davoust, De La Rosa, De Simoni, De Simoni, Di Napoli, Ducruet, Ducruet, Ducruet, Ducruet, Elvington, Elvington, Engstrom, Figueroa, Fisher, Frauenknecht, Garrett, Gasque, Gasque, Gesuete, Gill, Harboe, Harhausen, Heese, Heimann, Hoke, Holers, Huang, Huber-Lang, Hurtado, Iadecola, Imm, Jauneau, Katzan, Kim, Kramer, Kulik, Levi-Strauss, Lew, Li, Li, Lindsberg, Luo, Mack, McMullen, Mead, Mehta, Mocco, Mocco, Mocco, Moriyama, Morrison, Mukherjee, Mukherjee, Murphy, Olsson, Orsini, Osaka, Osthoff, Patel, Pavlovski, Pedersen, Pedersen, Pedersen, Persson, Pisalyaput, Rahpeymai, Ramaglia, Ricklin, Rogers, Rupprecht, Rynkowski, Schafer, Schafer, Schultz, Shinjyo, Soane, Somani, Speidl, Stahel, Stephan, Stevens, Stokowska, Stokowska, Storini, Széplaki, Ten, Ten, Thundyil, Thurman, Tohgi, Van Beek, Vasthare, Wieloch, Williams, Yang, Zee, Zhang, Zhang, Zhang, Zhang, Zhang, Zipfel   +129 more
core   +3 more sources

Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]

, 2020
Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P., Leuvenink, Henri G. D., Nieuwenhuijs-Moeke, Gertrude J., Pischke, Soren E., Ploeg, Rutger J., Pol, Robert A., Sanders, Jan Stephan F., Struys, Michel   +7 more
core   +2 more sources

The Disulfide Bonding Pattern in Ficolin Multimers [PDF]

Journal of Biological Chemistry, 2004
Ficolin is a plasma lectin, consisting of a short N-terminal multimerization domain, a middle collagen domain, and a C-terminal fibrinogen-like domain. The collagen domains assemble the subunits into trimers, and the N-terminal domain assembles four trimers into 12-mers.
Tomoo, Ohashi, Harold P, Erickson
openaire   +2 more sources

Genetic Susceptibility to Rheumatic Heart Disease: A Narrative Literature Review Highlighting Evidence From African Populations and Research Gaps in Sudan

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Rheumatic heart disease (RHD) remains a significant public health burden in low‐ and middle‐income countries, particularly in sub‐Saharan Africa. Although socioeconomic factors contribute to disease persistence, genetic susceptibility plays a critical role in determining progression from Group A Streptococcal infection to ...
Hussam Alkhalifamohamed, Waleed M. A. Jebreel, Mohamed Elhassan, Sulafa K. M. Ali   +3 more
wiley   +1 more source