The State of Prevention of Atopic Dermatitis: An Updated Review
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder that has a high worldwide prevalence and carries substantial psychosocial and financial burden. As such, the prevention of AD is an important area of research. In this review, we provide an update synthesizing relevant clinical trials published from January 2020 through July 2025 ...
Alexandra Kiszluk, Peter Lio
wiley +1 more source
Association of Gene Variations POMP, FLG, MTOR and ATG5 gene with the Risk of Asthma in Children
The aim of this study was to determine the correlation between single-nucleotide polymorphisms in the proteasome maturation protein gene (POMP), filaggrin gene (FLG), mammalian target of rapamycin gene (MTOR) and autophagy gene (ATG5) and the development
O.P. Volosovets +5 more
doaj +1 more source
Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz +13 more
wiley +1 more source
Early‐Life Secondhand Smoke Exposure and Development of Atopic Dermatitis up to Adulthood
Clinical &Experimental Allergy, EarlyView.
Anna Zettergren +11 more
wiley +1 more source
ABSTRACT Background Prebiotics, probiotics, postbiotics, and synbiotics have been increasingly investigated and incorporated into cosmetic formulations to preserve or restore skin health, function, and esthetics. Objective To review biotics applications in cosmetology, discussing their concepts, general characteristics, and potential benefits and ...
Guilherme Carvalho Tavares da Silva +7 more
wiley +1 more source
Royal jelly (RJ) is a natural product which the honeybee secretes as a special diet for a queen bee. It is one of the natural products in which various functionalities, such as antibacterial effects, immunomodulating properties, and estrogen-like action,
Lihao Gu, Haifeng Zeng, Kazuhisa Maeda
doaj +1 more source
Epistasis between FLG and IL4R genes on the risk of allergic sensitization: results from two population-based birth cohort studies [PDF]
Immune-specifc genes as well as genes responsible for the formation and integrity of the epidermal barrier have been implicated in the pathogeneses of allergic sensitization.
A Benedetto De +36 more
core +2 more sources
Skin Barrier Biomarkers in Patch‐Induced and Clinical Allergic and Irritant Contact Dermatitis
Both patch‐induced and clinical ICD and ACD showed consistent alterations in skin barrier‐associated biomarkers, indicative of skin barrier impairment. Among the tested allergens, chromium elicited more pronounced biomarker responses compared to nickel and methylisothiazolinone.
Sanja Kezic +8 more
wiley +1 more source
LD Hub:a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis [PDF]
Motivation: LD score regression is a reliable and efficient method of using genome-wide association study (GWAS) summary-level results data to estimate the SNP heritability of complex traits and diseases, partition this heritability into functional ...
Anttila, V. +19 more
core +2 more sources
This study compares experimental models of human skin barrier disruption and evaluates non‐invasive assessment methods. It highlights electrical impedance spectroscopy (EIS) as a novel tool of quantifying skin barrier damage and supports methodological standardisation and an improved understanding of barrier dysfunction under real‐world conditions ...
Charlotte Jasmin Kiani +7 more
wiley +1 more source

