Interindividual variability and its impact on the effectiveness of Janus kinase inhibitors in rheumatoid arthritis treatment [PDF]
Achieving the primary treat-to-target (T2T) goal in rheumatoid arthritis (RA) remains challenging for many patients, reflecting limitations in the effectiveness of existing treatments.
Corominas, Hèctor +4 more
core +1 more source
Effectiveness and safety of filgotinib in rheumatoid arthritis: a real-life multicentre experience [PDF]
Objectives: We investigated the effectiveness and safety of filgotinib in a real-life multicentre cohort of rheumatoid arthritis (RA) patients. Methods: RA patients were evaluated at baseline and after 12 and 24 weeks and were stratified based on ...
Aprile, Maria Letizia +21 more
core +1 more source
Assessing the construct validity of musculoskeletal ultrasound and the rheumatoid arthritis foot disease activity index (RADAI-F5) for managing rheumatoid foot disease [PDF]
, 2023 Dickson, Diane M. +3 more
core +1 more source
[Cost per Responder Analysis of Filgotinib in Patients Suffering from Ulcerative Colitis] [PDF]
OBJECTIVE: To evaluate the costs and benefits associated with the use of biologics and Janus kinase inhibitors (JAKi) for the treatment of bio-experienced patients suffering from ulcerative colitis in Italy.METHODS: This pharmacoeconomic analysis ...
Castello, Luca +3 more
core +3 more sources
Modern Strategies in the Pharmacotherapy of Inflammatory Bowel Diseases – A Literature Review [PDF]
Introduction and Aim:Inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis, are chronic, immune-mediated disorders of the gastrointestinal tract.
Boral, Aleksandra +8 more
core +1 more source
Adapted treatment of ANCA-associated vasculitis during the COVID-19 pandemic [PDF]
, 2021 Nimmo, Ailish, Risdale, Saira
core +2 more sources
The role of Janus kinase signaling in graft-versus-host disease and graft versus leukemia [PDF]
, 2018 Choi, Jaebok +3 more
core +2 more sources
Filgotinib in cutaneous lupus: is a negative positive? [PDF]
Rheumatology, 2021 Kathryn Connelly, Eric F Morand
openaire +2 more sources
Focus on Filgotinib in Rheumatoid Arthritis: A Trial-Based Review
Mediterranean Journal of RheumatologyJanus kinases (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway is involved in pathophysiologic cascade of a notable number of rheumatic diseases. The development of JAK inhibitors has expanded treatment choices in rheumatoid arthritis (RA) with a sustained class-effect efficacy.
Skouvaklidou, Elpida +11 more
openaire +2 more sources