Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions. [PDF]
, 2008 The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
A.G. Sprecher +105 more
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A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova +5 more
doaj +1 more source
Characterization of an influenza virus pseudotyped with Ebolavirus glycoprotein [PDF]
, 2018 We have produced a new Ebola virus pseudotype: E-S-FLU, which can be handled in biosafety level-1/2 containment for laboratory analysis. E-S-FLU is a single cycle influenza virus coated with Ebolavirus glycoprotein, and it encodes enhanced green ...
Annaert, Wim +6 more
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[Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations].
Voprosy virusologii, 2021 Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the largest of which escalated into an epidemic in 2014-2016 and caused the death of more than 11,000 people.
I. V. Dolzhikova +3 more
openaire +2 more sources
T-Cell Response to Viral Hemorrhagic Fevers
Vaccines, 2019 Viral hemorrhagic fevers (VHF) are a group of clinically similar diseases that can be caused by enveloped RNA viruses primarily from the families Arenaviridae, Filoviridae, Hantaviridae, and Flaviviridae.
Federico Perdomo-Celis +3 more
doaj +1 more source
Taxonomy of the order Mononegavirales : update 2016 [PDF]
, 2016 In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera
Afonso, Claudio L. +82 more
core +1 more source
Ebola virus disease 2014 [PDF]
, 2014 Ebola virus disease was irst described in 1976 originating from the Ebola River in the Democratic Republic of Congo. Since then, Ebola virus has become an important public health threat in Africa, and now it is of great concern worldwide due to the ...
Arellanos Soto, Daniel +4 more
core
Ebola Virus Infection: a review on the pharmacokinetic and pharmacodynamic properties of drugs considered for testing in human efficacy trials [PDF]
, 2016 International audienceThe 2014-2015 outbreak of Ebola virus disease (EVD) is the largest epidemic to date in terms of number of cases, of death and affected areas. In October 2015, no antiviral agents had proven an antiviral efficacy in patients. However
De Lamballerie, Xavier +6 more
core +3 more sources
Re-emerging infectious diseases: Ebola hemorrhagic fever [PDF]
Romanian Journal of Military Medicine, 2014 The spring of 2014 has brought a new calamity, the exotic infectious disease: Ebola Hemorrhagic Fever, which is caused by a highly contagious and pathogenic virus, transmitted directly by interpersonal contact or indirectly by common usage of objects ...
Lucia E. Ionescu +2 more
doaj
Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway
Genomics Data, 2016 The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3).
R.R. Green +5 more
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