Results 71 to 80 of about 4,558 (162)

Doença Causada por Filovírus: Uma Atualização

Acta Médica Portuguesa
Os vírus Marburgo e Ébola pertencem à família Filoviridae e são conhecidos por causar doenças zoonóticas emergentes. Estes vírus apresentam alta letalidade e são facilmente transmissíveis de pessoa para pessoa, o que os torna potencialmente capazes de ...
Rafael Marx de Andrade, Andreia Paulos, Emília Valadas, Vitor Laerte Pinto Junior   +3 more
doaj   +1 more source

Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway

Genomics Data, 2016
The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3).
R.R. Green, C. Wilkins, S. Pattabhi, R. Dong, Y. Loo, M. Gale, Jr   +5 more
doaj   +1 more source

[Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations].

Voprosy virusologii, 2021
Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the largest of which escalated into an epidemic in 2014-2016 and caused the death of more than 11,000 people.
I. V. Dolzhikova, D. N. Shcherbinin, D. Yu. Logunov, A. L. Gintsburg   +3 more
openaire   +2 more sources

Developments in Negative-Strand RNA Virus Reverse Genetics

Microorganisms
Many epidemics are caused by negative-stranded RNA viruses, leading to serious disease outbreaks that threaten human life and health. These viruses also have a significant impact on animal husbandry, resulting in substantial economic losses and ...
Mengyi Wang, Jinyan Wu, Xiaoan Cao, Long Xu, Junhuang Wu, Haiyan Ding, Youjun Shang   +6 more
doaj   +1 more source

Filoviridae [PDF]

, 2020
openaire   +1 more source

FORMACIÓN DE PORO EN MEMBRANA CELULAR POR MEDIO DE LA PEQUEÑA GLICOPROTEÍNA DE SECRECIÓN DEL VIRUS DE EBOLA ZAIRE

Universitas Scientiarum, 2004
Uno de los patógenos capaces de inducir fiebres hemorrágicas es el virus de Ebola, clasificado en la familia filoviridae con cuatro subtipos, de los cuales el más analizado es el subtipo de Ebola Zaire, identificando en su genoma siete proteínas ...
Nury EsperanzaVargas-Alejo, Clara Andrea Rincón-Cortés, Edgar Antonio Reyes-Montaño   +2 more
doaj  

Ebola Virus-A Review

Sokoto Journal of Medical Laboratory Science, 2018
Ebola virus (EBOV) is a single stranded zoonotic RNA virus of positive sense polarity under Filoviridae family, with no geographic, socio-economic, ethnic, gender or age boundaries, introduced to humans via contact with body fluids and products of wild ...
Rogo, L.D., Auwal, A.K.*
doaj  

Structural basis for Ebola virus nucleocapsid assembly and function regulated by VP24

Nature Communications
The Ebola virus, a member of the Filoviridae family, causes severe hemorrhagic fever in humans. Filamentous virions contain a helical nucleocapsid responsible for genome transcription, replication, and packaging into progeny virions.
Yoko Fujita-Fujiharu, Shangfan Hu, Ai Hirabayashi, Yuki Takamatsu, Yen Ni Ng, Kazuya Houri, Yukiko Muramoto, Masahiro Nakano, Yukihiko Sugita, Takeshi Noda   +9 more
doaj   +1 more source

Filoviridae: a Taxonomic Home for Marburg and Ebola Viruses ? [PDF]

Intervirology, 1982
M P, Kiley, E T, Bowen, G A, Eddy, M, Isaäcson, K M, Johnson, J B, McCormick, F A, Murphy, S R, Pattyn, D, Peters, O W, Prozesky, R L, Regnery, D I, Simpson, W, Slenczka, P, Sureau, G, van der Groen, P A, Webb, H, Wulff   +16 more
openaire   +2 more sources

Development of a broad-lineage Lassa virus rapid diagnostic test informed by the WHO REASSURED framework. [PDF]

J Clin Microbiol
Shin H, Lee M, Choi M-M, Kim J-W, Yi H, Whitmer S, Sayyad L, Montgomery J, Klena J, Chung Y-S.   +9 more
europepmc   +1 more source