Results 71 to 80 of about 3,948 (186)

Utilizing non‐human primate models to combat recent COVID‐19/SARS‐CoV‐2 and viral infectious disease outbreaks

open access: yesJournal of Medical Primatology, Volume 53, Issue 1, February 2024.
Abstract In recent times, global viral outbreaks and diseases, such as COVID‐19 (SARS‐CoV‐2), Zika (ZIKV), monkeypox (MPOX), Ebola (EBOV), and Marburg (MARV), have been extensively documented. Swiftly deciphering the mechanisms underlying disease pathogenesis and devising vaccines or therapeutic interventions to curtail these outbreaks stand as ...
Taeho Kwon
wiley   +1 more source

PAirwise Sequence Comparison (PASC) and Its Application in the Classification of Filoviruses

open access: yesViruses, 2012
PAirwise Sequence Comparison (PASC) is a tool that uses genome sequence similarity to help with virus classification. The PASC tool at NCBI uses two methods: local alignment based on BLAST and global alignment based on Needleman-Wunsch algorithm.
Tatiana Tatusova   +2 more
doaj   +1 more source

Novel antiviral discoveries for Japanese encephalitis virus infections through reporter virus‐based high‐throughput screening

open access: yesJournal of Medical Virology, Volume 96, Issue 1, January 2024.
Abstract Japanese encephalitis (JE) caused by JE virus (JEV), remains a global public health concern. Currently, there is no specific antiviral drug approved for the treatment of JE. While vaccines are available for prevention, they may not cover all at‐risk populations. This underscores the urgent need for prophylaxis and potent anti‐JEV drugs.
Chunhong Yin   +7 more
wiley   +1 more source

LLOVIU VIRUS - A NOVEL FILOVIRUS, ENDEMIC IN EUROPE

open access: yesВопросы вирусологии, 2018
The data on a recently revealed novel filovirus (Lloviu virus, family Filoviridae, genera Cuevavirus) in Europe are viewed in this issue. The molecular-biological properties of genome fragments of Lloviu virus were isolated from perished bats ...
T. E. Sizikova   +3 more
doaj   +1 more source

Experimental Infection of Bundibugyo Virus in Domestic Swine Leads to Viral Shedding with Evidence of Intraspecies Transmission

open access: yesTransboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
The Ebolavirus genus contains several of the deadliest zoonotic viruses known. One of these, Bundibugyo virus (BDBV), has been the causative agent of two outbreaks of human disease that have resulted in 211 known cases with a case fatality rate of 33.6%.
Charles E. Lewis   +8 more
wiley   +1 more source

Exploring the Immunopathogenesis of Viral Hemorrhagic Fever in Mice with a Humanized Immune System

open access: yesFrontiers in Immunology, 2017
Viral hemorrhagic fever (VHF) as a disease entity was first codified in the 1930s by soviet scientists investigating patients suffering from hantavirus infection. The group of hemorrhagic fever viruses (HFVs) has since expanded to include members from at
Günther Schönrich, Martin J. Raftery
doaj   +1 more source

A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2018
Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova   +5 more
doaj   +1 more source

Marburgvirus in Egyptian Fruit Bats, Zambia

open access: yesEmerging Infectious Diseases, 2019
We detected Marburg virus genome in Egyptian fruit bats (Rousettus aegyptiacus) captured in Zambia in September 2018. The virus was closely related phylogenetically to the viruses that previously caused Marburg outbreaks in the Democratic Republic of the
Masahiro Kajihara   +19 more
doaj   +1 more source

Remdesivir (GS-5734) Impedes Enterovirus Replication Through Viral RNA Synthesis Inhibition

open access: yesFrontiers in Microbiology, 2020
Human enteroviruses are responsible for diverse diseases, from mild respiratory symptoms to fatal neurological complications. Currently, no registered antivirals have been approved for clinical therapy.
Wei Ye   +16 more
doaj   +1 more source

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