Results 81 to 90 of about 6,987 (215)
MSAViewer:interactive JavaScript visualization of multiple sequence alignments [PDF]
, 2016 Summary: The MSAViewer is a quick and easy visualization and analysis JavaScript component for Multiple Sequence Alignment data of any size. Core features include interactive navigation through the alignment, application of popular color schemes, sorting,
Benedikt Rauscher +11 more
core +4 more sources
A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection
Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi +9 more
wiley +1 more source
Ebola virus disease 2014 [PDF]
, 2014 Ebola virus disease was irst described in 1976 originating from the Ebola River in the Democratic Republic of Congo. Since then, Ebola virus has become an important public health threat in Africa, and now it is of great concern worldwide due to the ...
Arellanos Soto, Daniel +4 more
core
Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe +17 more
wiley +1 more source
Genetically Diverse Filoviruses in Rousettus and Eonycteris spp. Bats, China, 2009 and 2015
Emerging Infectious Diseases, 2017 Genetically divergent filoviruses detected in Rousettus and Eonycteris spp. bats in China exhibited 61%–99% nt identity with reported filoviruses, based on partial replicase sequences, and they demonstrated lung tropism.
Xing-Lou Yang +13 more
doaj +1 more source
Mapping the zoonotic niche of Marburg virus disease in Africa. [PDF]
, 2015 BACKGROUND: Marburg virus disease (MVD) describes a viral haemorrhagic fever responsible for a number of outbreaks across eastern and southern Africa. It is a zoonotic disease, with the Egyptian rousette (Rousettus aegyptiacus) identified as a reservoir ...
Brady, Oliver J +7 more
core +2 more sources
Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
British Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier +4 more
wiley +1 more source
Ebola virus disease: past, present and future
Asian Pacific Journal of Tropical Biomedicine, 2015 Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%) accompanying with the disease. Ebola haemorrhagic fever (EHF) is an infectious disease of animal that can be transmitted to both human and ...
Harish Rajak +4 more
doaj +1 more source
Remdesivir (GS-5734) Impedes Enterovirus Replication Through Viral RNA Synthesis Inhibition
Frontiers in Microbiology, 2020 Human enteroviruses are responsible for diverse diseases, from mild respiratory symptoms to fatal neurological complications. Currently, no registered antivirals have been approved for clinical therapy.
Wei Ye +16 more
doaj +1 more source
A public, cross‐reactive glycoprotein epitope confounds Ebola virus serology
Journal of Medical Virology, Volume 96, Issue 10, October 2024.Abstract Ebola disease (EBOD) in humans is a severe disease caused by at least four related viruses in the genus Orthoebolavirus, most often by the eponymous Ebola virus. Due to human‐to‐human transmission and incomplete success in treating cases despite promising therapeutic development, EBOD is a high priority in public health research.
Markus H. Kainulainen +17 more
wiley +1 more source