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Filovirus Disease Outbreaks: A Chronological Overview [PDF]

open access: yesVirology: Research and Treatment, 2019
CITATION: Languon, S. & Quaye, O. 2019. Filovirus disease outbreaks : a chronological overview. Virology: Research and Treatment, 10:1-12, doi:10.1177/1178122X19849927.The original publication is available at https://journals.sagepub.comFiloviruses cause
Sylvester Languon, Osbourne Quaye
exaly   +2 more sources

Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover

open access: yesPLoS Neglected Tropical Diseases, 2019
Bats are reservoirs for several zoonotic pathogens, including filoviruses. Recent work highlights the diversity of bat borne filoviruses in Asia. High risk activities at the bat-human interface pose the threat of zoonotic virus transmission.
Gavin J.D. Smith   +2 more
exaly   +2 more sources
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Filovirus budding

Virus Research, 2004
Family Filoviridae, which includes Ebola virus (EBOV) and Marburg virus (MARV), is a growing threat to human and non-human primate populations in central Africa. Although many facets of the filovirus life cycle remain to be deciphered, a great deal has been learned in recent years. In particular, a clearer understanding of the roles played by viral, as
Luke D, Jasenosky, Yoshihiro, Kawaoka
openaire   +2 more sources

The Role of Cytokines and Chemokines in Filovirus Infection

open access: yesViruses, 2015
Ebola- and marburgviruses are highly pathogenic filoviruses and causative agents of viral hemorrhagic fever. Filovirus disease is characterized by a dysregulated immune response, severe organ damage, and coagulation abnormalities.
Arthur J Goff, Sandra L Bixler
exaly   +2 more sources

Filovirus helical nucleocapsid structures

Microscopy, 2022
Abstract Filoviruses are filamentous enveloped viruses belonging to the family Filoviridae, in the order Mononegavirales. Some filovirus members, such as Ebola virus and Marburg virus, cause severe hemorrhagic fever in humans and non-human primates.
Shangfan Hu, Takeshi Noda
openaire   +2 more sources

Discovery of an Ebolavirus-Like Filovirus in Europe

open access: yesPLoS Pathogens, 2011
(Uploaded by Plazi for the Bat Literature Project) Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and marburgviruses do not appear to be associated with disease.
Gustavo Palacios   +2 more
exaly   +10 more sources

Polymorphism of Filovirus Glycoproteins

2005
Publisher Summary Filoviral glycoproteins are encoded by gene 4 (GP gene) of the nonsegmented negative-strand RNA genome. Nonstructural glycoprotein (sGP) as well as Ebola virus (EBOV) and Marburgvirus (MBGV) GP undergo several posttranslational processing steps giving rise to a whole series of different glycoproteins.
Viktor E, Volchkov   +4 more
openaire   +2 more sources

Mechanisms of Filovirus Entry

2017
Filovirus entry into cells is complex, perhaps as complex as any viral entry mechanism identified to date. However, over the past 10 years, the important events required for filoviruses to enter into the endosomal compartment and fuse with vesicular membranes have been elucidated (Fig. 1).
R A, Davey   +5 more
openaire   +2 more sources

Filovirus Filament Proteins

2018
Filoviruses are highly filamentous enveloped animal viruses that can cause severe haemorrhagic fevers. The filovirus ribonucleoprotein forms a highly organized double-layered helical nucleocapsid (NC) containing five different virally encoded proteins. The inner layer consists of NP, the RNA binding protein, complexed with the monopartite linear genome.
Daniel R, Beniac   +2 more
openaire   +2 more sources

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