Results 161 to 170 of about 5,486 (195)
The mammalian SKI complex is a broad-spectrum antiviral drug target that upregulates cellular cholesterol to inhibit viral replication. [PDF]
J VirolWeston S +7 more
europepmc +1 more source
Targeting Host Dependency Factors: A Paradigm Shift in Antiviral Strategy Against RNA Viruses. [PDF]
Int J Mol SciYang J +8 more
europepmc +1 more source
Evaluating the impact of trade-offs in diagnostic test accuracy, time-to-isolation, and accessibility on outbreak response for the Ebola virus: a mathematical modeling study. [PDF]
BMC Infect DisBoer NA +4 more
europepmc +1 more source
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2010
Abstract Filoviruses are large RNA viruses, of which Ebola virus and Marburg virus cause the most severe forms of viral haemorrhagic fever and have been best-studied because of fear of their misuse as bioterrorism agents. These are zoonotic viruses with reservoirs, most likely fruit-eating bats, in the rainforests of tropical Africa ...
Dieudonné Nkoghe +3 more
+5 more sources
Abstract Filoviruses are large RNA viruses, of which Ebola virus and Marburg virus cause the most severe forms of viral haemorrhagic fever and have been best-studied because of fear of their misuse as bioterrorism agents. These are zoonotic viruses with reservoirs, most likely fruit-eating bats, in the rainforests of tropical Africa ...
Dieudonné Nkoghe +3 more
+5 more sources
Reverse Genetics Systems for Filoviruses
2023Filoviruses are causative agents of severe hemorrhagic fevers with high case fatality rates in humans. For studies of virus biology and the subsequent development of countermeasures, reverse genetic systems, and especially those facilitating the generation of recombinant filoviruses, are indispensable.
Bianca S, Bodmer, Thomas, Hoenen
openaire +2 more sources
1993
Abstract The viral family known as the Filoviridae is unique among animal virus families: we understand virtually nothing about the natural history and maintenance strategies of any member of the family, yet Marburg and Ebola viruses are highly pathogenic for man and are capable of epidemic transmission (Table 15.1). Surely they are a
C J Peters +8 more
openaire +1 more source
Abstract The viral family known as the Filoviridae is unique among animal virus families: we understand virtually nothing about the natural history and maintenance strategies of any member of the family, yet Marburg and Ebola viruses are highly pathogenic for man and are capable of epidemic transmission (Table 15.1). Surely they are a
C J Peters +8 more
openaire +1 more source
2017
(Uploaded by Plazi for the Bat Literature Project) Filoviruses can cause severe and often fatal disease in humans. To date, there have been 47 outbreaks resulting in more than 31,500 cases of human illness and over 13,200 reported deaths. Since their discovery, researchers from many scientific disciplines have worked to better understand the natural ...
Brian R, Amman +3 more
openaire +2 more sources
(Uploaded by Plazi for the Bat Literature Project) Filoviruses can cause severe and often fatal disease in humans. To date, there have been 47 outbreaks resulting in more than 31,500 cases of human illness and over 13,200 reported deaths. Since their discovery, researchers from many scientific disciplines have worked to better understand the natural ...
Brian R, Amman +3 more
openaire +2 more sources