Results 71 to 80 of about 13,264 (267)

Human urine decreases function and expression of type 1 pili in uropathogenic Escherichia coli [PDF]

open access: yes, 2015
Uropathogenic Escherichia coli (UPEC) is the primary cause of community-acquired urinary tract infections (UTIs). UPEC bind the bladder using type 1 pili, encoded by the fim operon in nearly all E. coli.
Chen, Swaine L   +4 more
core   +3 more sources

Adhesion of Escherichia coli under flow conditions reveals potential novel effects of FimH mutations [PDF]

open access: yes, 2016
FimH-mediated adhesion of Escherichia coli to bladder epithelium is a prerequisite for urinary tract infections. FimH is also essential for blood-borne bacterial dissemination, but the mechanisms are poorly understood.
Aarestrup, Frank Møller   +10 more
core   +3 more sources

Ligands for FimH [PDF]

open access: yes, 2011
Adhesion of bacteria to glycosylated cells and surfaces is largely facilitated through adhesive organells projecting from the bacterial surface, which are called fimbriae. The most important fimbriae in Escherichia coli and in most of the other enterobacteria are the type 1 fimbriae which mediate adhesion in an α-D-mannoside-specific manner. The lectin
openaire   +1 more source

Frequency of fimH, papC, and aer in E. coli Strains Isolated from Patients with Urinary Tract Infection, and their Antibiotic Resistance Pattern

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021
Introduction: E. coli is the predominant causes of urinary tract infection. Several virulence factors for bacterial infections in the urinary tract are required.
Zahra Abdolahzadeh   +4 more
doaj  

Ordered and ushered; the assembly and translocation of the adhesive Type I and P Pili [PDF]

open access: yes, 2013
Type I and P pili are chaperone-usher pili of uropathogenic Escherichia coli, which allow bacteria to adhere to host cell receptors. Pilus formation and secretion are orchestrated by two accessory proteins, a chaperone, which catalyses pilus subunit ...
Aberg   +19 more
core   +2 more sources

Flagella, Type I Fimbriae and Curli of Uropathogenic Escherichia coli Promote the Release of Proinflammatory Cytokines in a Coculture System

open access: yesMicroorganisms, 2021
Background. Urinary tract infections (UTIs) are a public health problem in Mexico, and uropathogenic Escherichia coli (UPEC) is one of the main etiological agents. Flagella, type I fimbriae, and curli promote the ability of these bacteria to successfully
Rubí Vega-Hernández   +9 more
doaj   +1 more source

Segmentation of Myocardial Boundaries in Tagged Cardiac MRI Using Active Contours: A Gradient-Based Approach Integrating Texture Analysis [PDF]

open access: yes, 2009
The noninvasive assessment of cardiac function is of first importance for the diagnosis of cardiovascular diseases. Among all medical scanners only a few enables radiologists to evaluate the local cardiac motion. Tagged cardiac MRI is one of them.
Histace, Aymeric   +2 more
core   +5 more sources

Glycan-Adhering Lectins and Experimental Evaluation of a Lectin FimH Inhibitor in Enterohemorrhagic Escherichia coli (EHEC) O157:H7 Strain EDL933

open access: yesInternational Journal of Molecular Sciences, 2022
In this study, we tried to develop a FimH inhibitor that inhibits adhesion of enterohemorrhagic Escherichia coli (EHEC) on the epithelium of human intestine during the initial stage of infections.
Jun-Young Park   +2 more
semanticscholar   +1 more source

Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization [PDF]

open access: yes, 2013
OBJECTIVES: To identify and to characterize small-molecule inhibitors that target the subunit polymerization of the type 1 pilus assembly in uropathogenic Escherichia coli (UPEC).
A.W. Edith Chan   +64 more
core   +2 more sources

Insights from the molecular docking analysis of SGLT2 and FIMH to combat uropathogenicity

open access: yesBioinformation, 2022
SGLT2 inhibitors are a novel class of FDA approved anti-diabetes drugs. They act by blocking the SGLT2 protein, which prevents glucose reabsorption, leading in enhance glucose excretion and lower blood glucose levels.
W. Abdulaal   +6 more
semanticscholar   +1 more source

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