Results 11 to 20 of about 21,222 (177)

Finasteride Side Effects and Post-Finasteride Syndrome in Male Androgenic Alopecia [PDF]

Journal of Mind and Medical Sciences, 2015
Finasteride is in present a relatively frequent prescribed drug for male androgenic alopecia. The adverse effects reported by some patients seem to be notable, consisting of various (physical, mental/ neurological, sexual, etc.) manifestations which are ...
Manea Mirela, Paunica Ioana, Puiu Gabriela Maria, Manea Costin Mihnea   +3 more
doaj   +11 more sources

The postfinasteride syndrome; an overview [PDF]

Journal of Mind and Medical Sciences, 2016
As a 5-α reductase inhibitor, Finasteride has proven effective in ameliorating two conditions documented to be androgen dependent, namely male androgenic alopecia and benign prostatic hyperplasia. Therapeutic results are maintained as long as the drug is
David L. Rowland, Ion G. Motofei, Florian Popa, Vlad D. Constantin, Adriana Vasilache, Ioana Paunica, Cristian Bălălău, Georgeta P. Păunică, Petrisor Banu, Stana Păunică   +9 more
doaj   +5 more sources

Finasteride adverse effects and post-finasteride syndrome; implications for dentists [PDF]

Journal of Mind and Medical Sciences, 2016
Finasteride is a 5α-reductase inhibitor widely used in present in the therapeutic approach of androgenic alopecia. Adverse effects consist in variable sign and symptoms, the most common being represented by mental troubles (reduced feeling of life ...
Stana Paunica, Marina Giurgiu, Andrei Vasilache, Ioana Paunica, Ion Motofei, Adriana Vasilache, Horia Traian Dumitriu, Anca Silvia Dumitriu   +7 more
doaj   +5 more sources

Dihydrotestosterone and Finasteride Effects on Alcohol Cue-Elicited Brain Activity in Males With Heavy Episodic Drinking. [PDF]

Addict Biol
In a randomized, double‐blind, placebo‐controlled crossover study, we investigated whether finasteride‐induced reduction of dihydrotestosterone alters alcohol cue‐elicited brain activity and craving in males with heavy episodic drinking. Although dihydrotestosterone concentrations were not associated with neural cue reactivity, finasteride increased ...
Boroumand-Jazi R, Hoffmann S, Reinhard I, Bach P, Sommer WH, Kundlacz M, Müller CP, Reichl M, Tan H, Wenger LP, Beck A, Vollstädt-Klein S, Kiefer F, Mühle C, Gerhardt S, Lenz B.   +15 more
europepmc   +2 more sources

Phytochemical Profiling of the Halophyte Artemisia fukudo Makino and Its In Vitro Effects on Androgen-Related Pathways Associated With Benign Prostatic Hyperplasia and Alopecia. [PDF]

ChemistryOpen
This study investigated the phytochemical constituents of the halophyte Artemisia fukudo, leading to the isolation and identification of eight compounds characterized by HPLC–DAD and ESI–MS. Importantly, we demonstrate for the first time that jaceidin inhibits 5α‐reductase type 2 and downregulates BPH‐associated proteins (AR, PSA, and PCNA) in prostate
Kim YN, Lee JS, Park MG, Kim YJ, Lee SM, Hwang KH, Yang MH, Kwon BO, Rho JR, Jeong EJ.   +9 more
europepmc   +2 more sources

Finasteride withdrawal induces anxiety‐like behavior and novelty avoidance in adult male rats [PDF]

J Neuroendocrinol
Abstract Finasteride, an inhibitor of the enzyme 5alpha‐reductase, prescribed for benign prostatic hyperplasia and androgenetic alopecia, induces a wide variety of side effects during treatment and upon withdrawal, like sexual dysfunction and cognitive and psychological disorders, inducing the so‐called post‐finasteride syndrome (PFS).
Cioffi L, Diviccaro S, Chrostek G, Severino F, Giatti S, Scheggia D, Melcangi R.   +6 more
europepmc   +2 more sources

Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT [PDF]

, 2020
Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility.
Ahmed, M, Cieza-Borrella, C, Eeles, R, Goh, C, Kote-Jarai, Z, PRACTICAL consortium, Saunders, E, Schumacher, FR   +7 more
core   +2 more sources

Inflammation in benign prostate tissue and prostate cancer in the finasteride arm of the Prostate Cancer Prevention Trial [PDF]

, 2016
BACKGROUND: A previous analysis of the placebo arm of the Prostate Cancer Prevention Trial (PCPT) reported 82% overall prevalence of intraprostatic inflammation and identified a link between inflammation and higher-grade prostate cancer and serum PSA ...
Barber, John R, De Marzo, Angelo M, Drake, Charles G, Goodman, Phyllis J, Gurel, Bora, Kristal, Alan R, Lippman, Scott M, Lucia, M. Scott, Murtola, Teemu J, Nelson, William G, Parnes, Howard L, Peskoe, Sarah B, Platz, Elizabeth A, Sutcliffe, Siobhan, Thompson, Ian M, Jr., Umbehr, Martin   +15 more
core   +2 more sources

Are Hand Preference and Sexual Orientation Possible Predicting Factors for Finasteride Adverse Effects in Male Androgenic Alopecia? [PDF]

, 2016
Sexual side effects of finasteride seem to be redoubtable, being encountered not only during therapy but also after treatment cessation. Consequently, any possible clinical/paraclinical elements that might predict these adverse effects would be useful in
Berglund, Hu, Irwig, Mondaini, Motofei, Motofei, Motofei, Savic, Savic   +8 more
core   +2 more sources

Antibody-Capped Mesoporous Nanoscopic Materials:Design of a Probe for the Selective Chromo-FluorogenicDetection of Finasteride [PDF]

, 2012
[EN] The synthesis of capped mesoporous silica nanoparticles (MSN) conjugated with an antibody (AB) as a gatekeeper has been carried out in order to obtain a delivery system able to release an entrapped cargo (dye) in the presence of a target molecule
Amoros del Toro, Pedro, Brun Sánchez, Eva María, Climent Terol, Estela, Maquieira Catala, Ángel, Marcos Martínez, María Dolores, Martínez Mañez, Ramón, Sancenón Galarza, Félix, Soto Camino, Juan   +7 more
core   +2 more sources